3K40

Crystal structure of Drosophila 3,4-dihydroxyphenylalanine decarboxylase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004058	molecular_function	aromatic-L-amino-acid decarboxylase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006520	biological_process	amino acid metabolic process
A	0006584	biological_process	catecholamine metabolic process
A	0006585	biological_process	dopamine biosynthetic process from tyrosine
A	0006587	biological_process	serotonin biosynthetic process from L-tryptophan
A	0007615	biological_process	anesthesia-resistant memory
A	0007616	biological_process	long-term memory
A	0009611	biological_process	response to wounding
A	0016829	molecular_function	lyase activity
A	0016830	molecular_function	carbon-carbon lyase activity
A	0016831	molecular_function	carboxy-lyase activity
A	0019752	biological_process	carboxylic acid metabolic process
A	0030170	molecular_function	pyridoxal phosphate binding
A	0035220	biological_process	wing disc development
A	0036467	molecular_function	5-hydroxy-L-tryptophan decarboxylase activity
A	0036468	molecular_function	L-dopa decarboxylase activity
A	0040040	biological_process	thermosensory behavior
A	0042423	biological_process	catecholamine biosynthetic process
A	0042427	biological_process	serotonin biosynthetic process
A	0042542	biological_process	response to hydrogen peroxide
A	0043052	biological_process	thermotaxis
A	0048082	biological_process	regulation of adult chitin-containing cuticle pigmentation
A	0048085	biological_process	adult chitin-containing cuticle pigmentation
B	0003824	molecular_function	catalytic activity
B	0004058	molecular_function	aromatic-L-amino-acid decarboxylase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006520	biological_process	amino acid metabolic process
B	0006584	biological_process	catecholamine metabolic process
B	0006585	biological_process	dopamine biosynthetic process from tyrosine
B	0006587	biological_process	serotonin biosynthetic process from L-tryptophan
B	0007615	biological_process	anesthesia-resistant memory
B	0007616	biological_process	long-term memory
B	0009611	biological_process	response to wounding
B	0016829	molecular_function	lyase activity
B	0016830	molecular_function	carbon-carbon lyase activity
B	0016831	molecular_function	carboxy-lyase activity
B	0019752	biological_process	carboxylic acid metabolic process
B	0030170	molecular_function	pyridoxal phosphate binding
B	0035220	biological_process	wing disc development
B	0036467	molecular_function	5-hydroxy-L-tryptophan decarboxylase activity
B	0036468	molecular_function	L-dopa decarboxylase activity
B	0040040	biological_process	thermosensory behavior
B	0042423	biological_process	catecholamine biosynthetic process
B	0042427	biological_process	serotonin biosynthetic process
B	0042542	biological_process	response to hydrogen peroxide
B	0043052	biological_process	thermotaxis
B	0048082	biological_process	regulation of adult chitin-containing cuticle pigmentation
B	0048085	biological_process	adult chitin-containing cuticle pigmentation

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 476

Chain	Residue
A	MET1
A	GLU2
A	HOH781
B	TYR366
B	ASN370
B	HOH599

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Functional Information from PROSITE/UniProt

site_id	PS00392
Number of Residues	22
Details	DDC_GAD_HDC_YDC DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. SFnFnphKWMlVnFDCsaMWlK

Chain	Residue	Details
A	SER295-LYS316

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"evidences":[{"source":"PubMed","id":"20098687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29037755","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20098687","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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