Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3K3R

Unrefined crystal structure of a LexA-DNA complex

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0000976	molecular_function	transcription cis-regulatory region binding
E	0001217	molecular_function	DNA-binding transcription repressor activity
E	0003677	molecular_function	DNA binding
E	0004252	molecular_function	serine-type endopeptidase activity
E	0005515	molecular_function	protein binding
E	0005829	cellular_component	cytosol
E	0006260	biological_process	DNA replication
E	0006281	biological_process	DNA repair
E	0006351	biological_process	DNA-templated transcription
E	0006355	biological_process	regulation of DNA-templated transcription
E	0006508	biological_process	proteolysis
E	0006974	biological_process	DNA damage response
E	0009432	biological_process	SOS response
E	0016787	molecular_function	hydrolase activity
E	0032993	cellular_component	protein-DNA complex
E	0042802	molecular_function	identical protein binding
E	0043565	molecular_function	sequence-specific DNA binding
E	0045892	biological_process	negative regulation of DNA-templated transcription
F	0000976	molecular_function	transcription cis-regulatory region binding
F	0001217	molecular_function	DNA-binding transcription repressor activity
F	0003677	molecular_function	DNA binding
F	0004252	molecular_function	serine-type endopeptidase activity
F	0005515	molecular_function	protein binding
F	0005829	cellular_component	cytosol
F	0006260	biological_process	DNA replication
F	0006281	biological_process	DNA repair
F	0006351	biological_process	DNA-templated transcription
F	0006355	biological_process	regulation of DNA-templated transcription
F	0006508	biological_process	proteolysis
F	0006974	biological_process	DNA damage response
F	0009432	biological_process	SOS response
F	0016787	molecular_function	hydrolase activity
F	0032993	cellular_component	protein-DNA complex
F	0042802	molecular_function	identical protein binding
F	0043565	molecular_function	sequence-specific DNA binding
F	0045892	biological_process	negative regulation of DNA-templated transcription

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	DNA binding: {"description":"H-T-H motif","evidences":[{"source":"HAMAP-Rule","id":"MF_00015","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4
Details	Active site: {"description":"For autocatalytic cleavage activity","evidences":[{"source":"HAMAP-Rule","id":"MF_00015","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

Catalytic Information from CSA