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3K33

Crystal structure of the Phd-Doc complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0003677molecular_functionDNA binding
A0004674molecular_functionprotein serine/threonine kinase activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0006351biological_processDNA-templated transcription
A0016301molecular_functionkinase activity
A0016740molecular_functiontransferase activity
A0039604biological_processsymbiont-mediated suppression of host translation
A0044696biological_processkilling by virus of host cell by post-segregational killing
A0106310molecular_functionprotein serine kinase activity
B0001217molecular_functionDNA-binding transcription repressor activity
B0003677molecular_functionDNA binding
B0005515molecular_functionprotein binding
B0006351biological_processDNA-templated transcription
B0032993cellular_componentprotein-DNA complex
B0042803molecular_functionprotein homodimerization activity
B0043565molecular_functionsequence-specific DNA binding
B0045892biological_processnegative regulation of DNA-templated transcription
B0097351molecular_functiontoxin sequestering activity
C0001217molecular_functionDNA-binding transcription repressor activity
C0003677molecular_functionDNA binding
C0005515molecular_functionprotein binding
C0006351biological_processDNA-templated transcription
C0032993cellular_componentprotein-DNA complex
C0042803molecular_functionprotein homodimerization activity
C0043565molecular_functionsequence-specific DNA binding
C0045892biological_processnegative regulation of DNA-templated transcription
C0097351molecular_functiontoxin sequestering activity
D0001217molecular_functionDNA-binding transcription repressor activity
D0003677molecular_functionDNA binding
D0005515molecular_functionprotein binding
D0006351biological_processDNA-templated transcription
D0032993cellular_componentprotein-DNA complex
D0042803molecular_functionprotein homodimerization activity
D0043565molecular_functionsequence-specific DNA binding
D0045892biological_processnegative regulation of DNA-templated transcription
D0097351molecular_functiontoxin sequestering activity
Functional Information from PDB Data
site_idAC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE ACT C 101
ChainResidue
CALA51
CGLU55
CHOH108

site_idAC2
Number of Residues1
DetailsBINDING SITE FOR RESIDUE ACT D 201
ChainResidue
AASP93

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues116
DetailsDomain: {"description":"Fido","evidences":[{"source":"PROSITE-ProRule","id":"PRU00791","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues23
DetailsRegion: {"description":"Sufficient for antitoxin activity, its presence prevents formation of a doc-EF-Tu complex"}
ChainResidueDetails

247536

PDB entries from 2026-01-14

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