Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| B | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE JZI A 301 |
| Chain | Residue |
| A | HIS59 |
| A | LEU61 |
| A | LYS63 |
| A | CYS113 |
| A | SER114 |
| A | LEU122 |
| A | PHE134 |
| A | SER154 |
| A | HIS157 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE JZI B 302 |
| Chain | Residue |
| B | HOH2 |
| B | HIS59 |
| B | LEU61 |
| B | LYS63 |
| B | ARG68 |
| B | ARG69 |
| B | ARG69 |
| B | CYS113 |
| B | SER114 |
| B | LEU122 |
| B | PHE134 |
| B | SER154 |
| B | HIS157 |
| B | HOH177 |
Functional Information from PROSITE/UniProt
| site_id | PS01096 |
| Number of Residues | 21 |
| Details | PPIC_PPIASE_1 PpiC-type peptidyl-prolyl cis-trans isomerase signature. FEsLAsqfSdcs.Saka..RGdLG |
| Chain | Residue | Details |
| A | PHE103-GLY123 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 222 |
| Details | Domain: {"description":"PpiC","evidences":[{"source":"PROSITE-ProRule","id":"PRU00278","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine; by DAPK1","evidences":[{"source":"PubMed","id":"21497122","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29686383","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17525332","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 511 |
| Chain | Residue | Details |
| A | HIS59 | proton shuttle (general acid/base) |
| A | CYS113 | covalently attached, electrostatic stabiliser |
| A | GLN131 | electrostatic stabiliser |
| A | SER154 | electrostatic stabiliser |
| A | HIS157 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 511 |
| Chain | Residue | Details |
| B | HIS59 | proton shuttle (general acid/base) |
| B | CYS113 | covalently attached, electrostatic stabiliser |
| B | GLN131 | electrostatic stabiliser |
| B | SER154 | electrostatic stabiliser |
| B | HIS157 | electrostatic stabiliser |
