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3JVF

Crystal structure of an Interleukin-17 receptor complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0001819biological_processpositive regulation of cytokine production
A0002225biological_processpositive regulation of antimicrobial peptide production
A0002250biological_processadaptive immune response
A0005125molecular_functioncytokine activity
A0005126molecular_functioncytokine receptor binding
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006954biological_processinflammatory response
A0016525biological_processnegative regulation of angiogenesis
A0017015biological_processregulation of transforming growth factor beta receptor signaling pathway
A0019955molecular_functioncytokine binding
A0032645biological_processregulation of granulocyte macrophage colony-stimulating factor production
A0032663biological_processregulation of interleukin-2 production
A0032675biological_processregulation of interleukin-6 production
A0032677biological_processregulation of interleukin-8 production
A0032755biological_processpositive regulation of interleukin-6 production
A0032761biological_processpositive regulation of lymphotoxin A production
A0042803molecular_functionprotein homodimerization activity
A0045087biological_processinnate immune response
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0046982molecular_functionprotein heterodimerization activity
A0050829biological_processdefense response to Gram-negative bacterium
A0050830biological_processdefense response to Gram-positive bacterium
A0051216biological_processcartilage development
A0097400biological_processinterleukin-17-mediated signaling pathway
A1900017biological_processpositive regulation of cytokine production involved in inflammatory response
A2000340biological_processpositive regulation of chemokine (C-X-C motif) ligand 1 production
B0001819biological_processpositive regulation of cytokine production
B0002225biological_processpositive regulation of antimicrobial peptide production
B0002250biological_processadaptive immune response
B0005125molecular_functioncytokine activity
B0005126molecular_functioncytokine receptor binding
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0006954biological_processinflammatory response
B0016525biological_processnegative regulation of angiogenesis
B0017015biological_processregulation of transforming growth factor beta receptor signaling pathway
B0019955molecular_functioncytokine binding
B0032645biological_processregulation of granulocyte macrophage colony-stimulating factor production
B0032663biological_processregulation of interleukin-2 production
B0032675biological_processregulation of interleukin-6 production
B0032677biological_processregulation of interleukin-8 production
B0032755biological_processpositive regulation of interleukin-6 production
B0032761biological_processpositive regulation of lymphotoxin A production
B0042803molecular_functionprotein homodimerization activity
B0045087biological_processinnate immune response
B0045944biological_processpositive regulation of transcription by RNA polymerase II
B0046982molecular_functionprotein heterodimerization activity
B0050829biological_processdefense response to Gram-negative bacterium
B0050830biological_processdefense response to Gram-positive bacterium
B0051216biological_processcartilage development
B0097400biological_processinterleukin-17-mediated signaling pathway
B1900017biological_processpositive regulation of cytokine production involved in inflammatory response
B2000340biological_processpositive regulation of chemokine (C-X-C motif) ligand 1 production
C0030368molecular_functioninterleukin-17 receptor activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19838198, ECO:0000269|PubMed:23695682
ChainResidueDetails
CASN18
CASN23
CASN194

site_idSWS_FT_FI2
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19838198
ChainResidueDetails
CASN36
CASN234

site_idSWS_FT_FI3
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
CASN175
CASN211

226707

PDB entries from 2024-10-30

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