Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3JCK

Structure of the yeast 26S proteasome lid sub-complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000502	cellular_component	proteasome complex
A	0030234	molecular_function	enzyme regulator activity
A	0042176	biological_process	regulation of protein catabolic process
B	0000338	biological_process	protein deneddylation
B	0000502	cellular_component	proteasome complex
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0008180	cellular_component	COP9 signalosome
B	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
B	0034515	cellular_component	proteasome storage granule
B	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
C	0000502	cellular_component	proteasome complex
C	0005198	molecular_function	structural molecule activity
C	0005515	molecular_function	protein binding
C	0006511	biological_process	ubiquitin-dependent protein catabolic process
C	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
C	0034515	cellular_component	proteasome storage granule
C	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
C	0043248	biological_process	proteasome assembly
D	0000502	cellular_component	proteasome complex
D	0005198	molecular_function	structural molecule activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005838	cellular_component	proteasome regulatory particle
D	0006511	biological_process	ubiquitin-dependent protein catabolic process
D	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
D	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
E	0000502	cellular_component	proteasome complex
E	0005515	molecular_function	protein binding
E	0005838	cellular_component	proteasome regulatory particle
E	0006511	biological_process	ubiquitin-dependent protein catabolic process
E	0008233	molecular_function	peptidase activity
E	0008237	molecular_function	metallopeptidase activity
E	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
E	0034515	cellular_component	proteasome storage granule
E	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
F	0000502	cellular_component	proteasome complex
F	0005198	molecular_function	structural molecule activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005829	cellular_component	cytosol
F	0006511	biological_process	ubiquitin-dependent protein catabolic process
F	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
F	0034515	cellular_component	proteasome storage granule
F	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
F	0043248	biological_process	proteasome assembly
G	0000266	biological_process	mitochondrial fission
G	0000502	cellular_component	proteasome complex
G	0004843	molecular_function	cysteine-type deubiquitinase activity
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005739	cellular_component	mitochondrion
G	0005829	cellular_component	cytosol
G	0006508	biological_process	proteolysis
G	0008233	molecular_function	peptidase activity
G	0008234	molecular_function	cysteine-type peptidase activity
G	0008237	molecular_function	metallopeptidase activity
G	0008270	molecular_function	zinc ion binding
G	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
G	0016559	biological_process	peroxisome fission
G	0016579	biological_process	protein deubiquitination
G	0016787	molecular_function	hydrolase activity
G	0032436	biological_process	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
G	0034515	cellular_component	proteasome storage granule
G	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
G	0043248	biological_process	proteasome assembly
G	0046872	molecular_function	metal ion binding
G	0070628	molecular_function	proteasome binding
G	0140492	molecular_function	metal-dependent deubiquitinase activity
G	1902906	biological_process	proteasome storage granule assembly
H	0000502	cellular_component	proteasome complex
H	0003674	molecular_function	molecular_function
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005838	cellular_component	proteasome regulatory particle
H	0006508	biological_process	proteolysis
H	0006511	biological_process	ubiquitin-dependent protein catabolic process
H	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
H	0034515	cellular_component	proteasome storage granule
H	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
I	0000502	cellular_component	proteasome complex
I	0000724	biological_process	double-strand break repair via homologous recombination
I	0003674	molecular_function	molecular_function
I	0005515	molecular_function	protein binding
I	0005829	cellular_component	cytosol
I	0006351	biological_process	DNA-templated transcription
I	0006406	biological_process	mRNA export from nucleus
I	0006457	biological_process	protein folding
I	0006511	biological_process	ubiquitin-dependent protein catabolic process
I	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
I	0030447	biological_process	filamentous growth
I	0034515	cellular_component	proteasome storage granule
I	0035753	biological_process	maintenance of DNA trinucleotide repeats
I	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
I	0043248	biological_process	proteasome assembly
I	0044183	molecular_function	protein folding chaperone
I	0045944	biological_process	positive regulation of transcription by RNA polymerase II
I	0051726	biological_process	regulation of cell cycle
I	0060090	molecular_function	molecular adaptor activity
I	0070390	cellular_component	transcription export complex 2
I	0072742	biological_process	SAGA complex localization to transcription regulatory region

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN G 500

Chain	Residue
B	HOH501
G	HIS109
G	HIS111
G	ASP122

Functional Information from PROSITE/UniProt

site_id	PS00387
Number of Residues	7
Details	PPASE Inorganic pyrophosphatase signature. DDDEIDV

Chain	Residue	Details
E	ASP243-VAL249

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	683
Details	Domain: {"description":"PCI","evidences":[{"source":"PROSITE-ProRule","id":"PRU01185","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	33
Details	Repeat: {"description":"TPR"}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	13
Details	Motif: {"description":"JAMM motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)