Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3J7O

Structure of the mammalian 60S ribosomal subunit

This is a non-PDB format compatible entry.

Replaces: 3J71Replaces: 1VWWReplaces: 1VWX

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002181	biological_process	cytoplasmic translation
A	0003723	molecular_function	RNA binding
A	0003735	molecular_function	structural constituent of ribosome
A	0005840	cellular_component	ribosome
A	0006412	biological_process	translation
A	0015934	cellular_component	large ribosomal subunit
A	0022625	cellular_component	cytosolic large ribosomal subunit
A	0022626	cellular_component	cytosolic ribosome
A	0031090	cellular_component	organelle membrane
A	1990904	cellular_component	ribonucleoprotein complex
B	0003735	molecular_function	structural constituent of ribosome
B	0005840	cellular_component	ribosome
B	0006412	biological_process	translation
C	0003735	molecular_function	structural constituent of ribosome
C	0005840	cellular_component	ribosome
C	0006412	biological_process	translation
D	0003735	molecular_function	structural constituent of ribosome
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0008097	molecular_function	5S rRNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
F	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F	0003735	molecular_function	structural constituent of ribosome
F	0022625	cellular_component	cytosolic large ribosomal subunit
G	0042254	biological_process	ribosome biogenesis
G	1990904	cellular_component	ribonucleoprotein complex
H	0002181	biological_process	cytoplasmic translation
H	0003735	molecular_function	structural constituent of ribosome
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0019843	molecular_function	rRNA binding
H	0022625	cellular_component	cytosolic large ribosomal subunit
H	1990904	cellular_component	ribonucleoprotein complex
I	0003735	molecular_function	structural constituent of ribosome
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005730	cellular_component	nucleolus
J	0005737	cellular_component	cytoplasm
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0015934	cellular_component	large ribosomal subunit
J	0019843	molecular_function	rRNA binding
J	0022625	cellular_component	cytosolic large ribosomal subunit
J	0032435	biological_process	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
J	0034504	biological_process	protein localization to nucleus
J	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
J	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
J	1990904	cellular_component	ribonucleoprotein complex
L	0003735	molecular_function	structural constituent of ribosome
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
M	0003723	molecular_function	RNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005737	cellular_component	cytoplasm
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0015934	cellular_component	large ribosomal subunit
M	0022625	cellular_component	cytosolic large ribosomal subunit
M	0031090	cellular_component	organelle membrane
M	0042273	biological_process	ribosomal large subunit biogenesis
M	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
M	1990904	cellular_component	ribonucleoprotein complex
N	0003735	molecular_function	structural constituent of ribosome
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
O	0003735	molecular_function	structural constituent of ribosome
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0015934	cellular_component	large ribosomal subunit
P	0003735	molecular_function	structural constituent of ribosome
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0015934	cellular_component	large ribosomal subunit
Q	0002181	biological_process	cytoplasmic translation
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005737	cellular_component	cytoplasm
Q	0005783	cellular_component	endoplasmic reticulum
Q	0005791	cellular_component	rough endoplasmic reticulum
Q	0005829	cellular_component	cytosol
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0022625	cellular_component	cytosolic large ribosomal subunit
Q	0043232	cellular_component	intracellular non-membrane-bounded organelle
Q	1990904	cellular_component	ribonucleoprotein complex
R	0003723	molecular_function	RNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	0022625	cellular_component	cytosolic large ribosomal subunit
S	0003735	molecular_function	structural constituent of ribosome
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0022625	cellular_component	cytosolic large ribosomal subunit
T	0003735	molecular_function	structural constituent of ribosome
T	0005737	cellular_component	cytoplasm
T	0005783	cellular_component	endoplasmic reticulum
T	0005829	cellular_component	cytosol
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0022625	cellular_component	cytosolic large ribosomal subunit
T	0031090	cellular_component	organelle membrane
T	1990904	cellular_component	ribonucleoprotein complex
U	0002181	biological_process	cytoplasmic translation
U	0003723	molecular_function	RNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0005634	cellular_component	nucleus
U	0005737	cellular_component	cytoplasm
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0008201	molecular_function	heparin binding
U	0015934	cellular_component	large ribosomal subunit
U	0022625	cellular_component	cytosolic large ribosomal subunit
U	0022626	cellular_component	cytosolic ribosome
U	0042802	molecular_function	identical protein binding
U	0045202	cellular_component	synapse
U	0046632	biological_process	alpha-beta T cell differentiation
U	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
U	0098793	cellular_component	presynapse
U	0098978	cellular_component	glutamatergic synapse
U	0140236	biological_process	translation at presynapse
U	1990904	cellular_component	ribonucleoprotein complex
V	0000122	biological_process	negative regulation of transcription by RNA polymerase II
V	0001223	molecular_function	transcription coactivator binding
V	0003735	molecular_function	structural constituent of ribosome
V	0005654	cellular_component	nucleoplasm
V	0005730	cellular_component	nucleolus
V	0005737	cellular_component	cytoplasm
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0008284	biological_process	positive regulation of cell population proliferation
V	0010628	biological_process	positive regulation of gene expression
V	0015934	cellular_component	large ribosomal subunit
V	0022625	cellular_component	cytosolic large ribosomal subunit
V	0022626	cellular_component	cytosolic ribosome
V	0031625	molecular_function	ubiquitin protein ligase binding
V	0032986	biological_process	protein-DNA complex disassembly
V	0032991	cellular_component	protein-containing complex
V	0045202	cellular_component	synapse
V	0050821	biological_process	protein stabilization
V	0070180	molecular_function	large ribosomal subunit rRNA binding
V	0070314	biological_process	G1 to G0 transition
V	0072717	biological_process	cellular response to actinomycin D
V	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
V	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
V	1903450	biological_process	regulation of G1 to G0 transition
V	1990904	cellular_component	ribonucleoprotein complex
V	1990948	molecular_function	ubiquitin ligase inhibitor activity
V	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
X	0003735	molecular_function	structural constituent of ribosome
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0019843	molecular_function	rRNA binding
Y	0002181	biological_process	cytoplasmic translation
Y	0003723	molecular_function	RNA binding
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005654	cellular_component	nucleoplasm
Y	0005730	cellular_component	nucleolus
Y	0005737	cellular_component	cytoplasm
Y	0005840	cellular_component	ribosome
Y	0006364	biological_process	rRNA processing
Y	0006412	biological_process	translation
Y	0006977	biological_process	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
Y	0015934	cellular_component	large ribosomal subunit
Y	0022625	cellular_component	cytosolic large ribosomal subunit
Y	0022626	cellular_component	cytosolic ribosome
Y	0031090	cellular_component	organelle membrane
Y	0034644	biological_process	cellular response to UV
Y	0042273	biological_process	ribosomal large subunit biogenesis
Y	0045202	cellular_component	synapse
Y	0045727	biological_process	positive regulation of translation
Y	0048027	molecular_function	mRNA 5'-UTR binding
Y	0071479	biological_process	cellular response to ionizing radiation
Y	0071480	biological_process	cellular response to gamma radiation
Y	1902164	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
Y	1902167	biological_process	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
Y	1904803	biological_process	regulation of translation involved in cellular response to UV
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005654	cellular_component	nucleoplasm
Z	0005730	cellular_component	nucleolus
Z	0005737	cellular_component	cytoplasm
Z	0005783	cellular_component	endoplasmic reticulum
Z	0005791	cellular_component	rough endoplasmic reticulum
Z	0005829	cellular_component	cytosol
Z	0005840	cellular_component	ribosome
Z	0006364	biological_process	rRNA processing
Z	0006412	biological_process	translation
Z	0015934	cellular_component	large ribosomal subunit
Z	0022625	cellular_component	cytosolic large ribosomal subunit
Z	0022626	cellular_component	cytosolic ribosome
Z	0031090	cellular_component	organelle membrane
Z	0045202	cellular_component	synapse
Z	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
Z	1990904	cellular_component	ribonucleoprotein complex
a	0003735	molecular_function	structural constituent of ribosome
a	0005840	cellular_component	ribosome
a	0006412	biological_process	translation
a	0015934	cellular_component	large ribosomal subunit
b	0002181	biological_process	cytoplasmic translation
b	0003735	molecular_function	structural constituent of ribosome
b	0005737	cellular_component	cytoplasm
b	0005840	cellular_component	ribosome
b	0006412	biological_process	translation
b	0015934	cellular_component	large ribosomal subunit
b	0022625	cellular_component	cytosolic large ribosomal subunit
b	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
b	1990904	cellular_component	ribonucleoprotein complex
c	0003723	molecular_function	RNA binding
c	0003735	molecular_function	structural constituent of ribosome
c	0022625	cellular_component	cytosolic large ribosomal subunit
d	0002181	biological_process	cytoplasmic translation
d	0003735	molecular_function	structural constituent of ribosome
d	0005737	cellular_component	cytoplasm
d	0005840	cellular_component	ribosome
d	0006412	biological_process	translation
d	0015934	cellular_component	large ribosomal subunit
d	0022625	cellular_component	cytosolic large ribosomal subunit
d	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
d	1990904	cellular_component	ribonucleoprotein complex
e	0002181	biological_process	cytoplasmic translation
e	0003735	molecular_function	structural constituent of ribosome
e	0005737	cellular_component	cytoplasm
e	0005840	cellular_component	ribosome
e	0006412	biological_process	translation
e	0015934	cellular_component	large ribosomal subunit
e	0022625	cellular_component	cytosolic large ribosomal subunit
e	0022626	cellular_component	cytosolic ribosome
e	0045202	cellular_component	synapse
e	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
e	1990904	cellular_component	ribonucleoprotein complex
f	0003735	molecular_function	structural constituent of ribosome
f	0005840	cellular_component	ribosome
f	0006412	biological_process	translation
g	0003735	molecular_function	structural constituent of ribosome
g	0005730	cellular_component	nucleolus
g	0005737	cellular_component	cytoplasm
g	0005783	cellular_component	endoplasmic reticulum
g	0005829	cellular_component	cytosol
g	0005840	cellular_component	ribosome
g	0006412	biological_process	translation
g	0022625	cellular_component	cytosolic large ribosomal subunit
g	0022626	cellular_component	cytosolic ribosome
g	0045202	cellular_component	synapse
g	1990904	cellular_component	ribonucleoprotein complex
h	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
h	0003729	molecular_function	mRNA binding
h	0003735	molecular_function	structural constituent of ribosome
h	0005737	cellular_component	cytoplasm
h	0005840	cellular_component	ribosome
h	0006412	biological_process	translation
h	0015934	cellular_component	large ribosomal subunit
h	0022625	cellular_component	cytosolic large ribosomal subunit
h	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
h	1990904	cellular_component	ribonucleoprotein complex
i	0003735	molecular_function	structural constituent of ribosome
i	0005840	cellular_component	ribosome
i	0006412	biological_process	translation
j	0003735	molecular_function	structural constituent of ribosome
j	0005840	cellular_component	ribosome
j	0006412	biological_process	translation
k	0003735	molecular_function	structural constituent of ribosome
k	0005840	cellular_component	ribosome
k	0006412	biological_process	translation
k	0022618	biological_process	protein-RNA complex assembly
k	0022625	cellular_component	cytosolic large ribosomal subunit
k	1990904	cellular_component	ribonucleoprotein complex
l	0002181	biological_process	cytoplasmic translation
l	0002227	biological_process	innate immune response in mucosa
l	0003735	molecular_function	structural constituent of ribosome
l	0005615	cellular_component	extracellular space
l	0005840	cellular_component	ribosome
l	0006412	biological_process	translation
l	0019731	biological_process	antibacterial humoral response
l	0022625	cellular_component	cytosolic large ribosomal subunit
l	0022626	cellular_component	cytosolic ribosome
l	0050830	biological_process	defense response to Gram-positive bacterium
l	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
l	1990904	cellular_component	ribonucleoprotein complex
m	0003723	molecular_function	RNA binding
m	0003735	molecular_function	structural constituent of ribosome
m	0005634	cellular_component	nucleus
m	0005737	cellular_component	cytoplasm
m	0005840	cellular_component	ribosome
m	0006412	biological_process	translation
m	0015934	cellular_component	large ribosomal subunit
m	0016567	biological_process	protein ubiquitination
m	0019941	biological_process	modification-dependent protein catabolic process
m	0022627	cellular_component	cytosolic small ribosomal subunit
m	0031386	molecular_function	protein tag activity
m	0031625	molecular_function	ubiquitin protein ligase binding
m	0043229	cellular_component	intracellular organelle
m	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
m	1990904	cellular_component	ribonucleoprotein complex
n	0003735	molecular_function	structural constituent of ribosome
n	0005840	cellular_component	ribosome
n	0006412	biological_process	translation
o	0003674	molecular_function	molecular_function
o	0003735	molecular_function	structural constituent of ribosome
o	0005737	cellular_component	cytoplasm
o	0005840	cellular_component	ribosome
o	0006412	biological_process	translation
o	0008150	biological_process	biological_process
o	0015934	cellular_component	large ribosomal subunit
o	0022625	cellular_component	cytosolic large ribosomal subunit
o	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
o	1990904	cellular_component	ribonucleoprotein complex
p	0003735	molecular_function	structural constituent of ribosome
p	0005840	cellular_component	ribosome
p	0006412	biological_process	translation
r	0003735	molecular_function	structural constituent of ribosome
r	0005840	cellular_component	ribosome
r	0006412	biological_process	translation

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5101

Chain	Residue
5	G2584
g	GLY55
g	THR70
g	HIS73

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5102

Chain	Residue
5	A39
5	U3915

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5103

Chain	Residue
5	C41
5	U37
5	A38
5	G40

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5104

Chain	Residue
5	U43
5	A44
5	U45

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5105

Chain	Residue
5	A47
5	G48

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5106

Chain	Residue
5	A51

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5107

Chain	Residue
5	G21
5	A56

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5108

Chain	Residue
5	A61
5	G63

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5109

Chain	Residue
5	A62
5	U333

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5110

Chain	Residue
5	A84
5	G85
5	G1383
5	C1384

site_id	BC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5112

Chain	Residue
5	A105

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5113

Chain	Residue
5	C112
5	G156

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5114

Chain	Residue
5	G114

site_id	BC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5115

Chain	Residue
5	A198
5	G240

site_id	BC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5116

Chain	Residue
5	A235

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5117

Chain	Residue
5	U231
5	A235

site_id	BC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5118

Chain	Residue
5	C282

site_id	BC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5119

Chain	Residue
5	G288
5	A4178

site_id	CC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5120

Chain	Residue
5	U291

site_id	CC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5121

Chain	Residue
5	A47
5	U291

site_id	CC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5122

Chain	Residue
5	U316
5	U4354

site_id	CC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5124

Chain	Residue
5	C351
5	G2343

site_id	CC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5126

Chain	Residue
5	G356
5	C358
C	GLY98

site_id	CC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5127

Chain	Residue
5	A355
5	G356
5	A359

site_id	CC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5128

Chain	Residue
5	A2332

site_id	CC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5129

Chain	Residue
5	A407
5	G2330
5	G2331

site_id	CC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5130

Chain	Residue
5	A410
5	G415
5	U416
5	G2331

site_id	DC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5131

Chain	Residue
5	G415
5	U416
5	G417

site_id	DC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG 5 5132

Chain	Residue
5	C422
5	G423
5	U424
8	A9
8	G10

site_id	DC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5134

Chain	Residue
5	C1665
5	A2279
5	G2280

site_id	DC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5135

Chain	Residue
5	A2282

site_id	DC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5136

Chain	Residue
5	A2367
5	U2828

site_id	DC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5137

Chain	Residue
5	A2368
5	A2370
5	U2826

site_id	DC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5138

Chain	Residue
5	C2393

site_id	DC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5139

Chain	Residue
5	A2401

site_id	DC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5140

Chain	Residue
5	C2410
5	C2411
5	A2428

site_id	EC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5141

Chain	Residue
5	C2422
5	A2423

site_id	EC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5142

Chain	Residue
5	G2510

site_id	EC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5143

Chain	Residue
5	G2514
5	G2516

site_id	EC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5144

Chain	Residue
5	G2677

site_id	EC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5145

Chain	Residue
5	G2402
5	A2783
5	C2784

site_id	EC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5146

Chain	Residue
5	A2789
5	G2827
5	U2828

site_id	EC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5147

Chain	Residue
5	C2792

site_id	EC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5148

Chain	Residue
5	A1599
5	A1600
5	G2793
5	C2794

site_id	EC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5149

Chain	Residue
5	A2845

site_id	FC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5150

Chain	Residue
5	A2857

site_id	FC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5151

Chain	Residue
5	A2879
5	A3629

site_id	FC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5152

Chain	Residue
5	C3632

site_id	FC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5153

Chain	Residue
5	G3634
5	C3636

site_id	FC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5154

Chain	Residue
5	A3642
5	U3644
5	U3645

site_id	FC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5155

Chain	Residue
5	C3701
5	U3704
5	G3705
5	U3745

site_id	FC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5156

Chain	Residue
5	G3689
5	A3747
5	A3748
5	U3818

site_id	FC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5158

Chain	Residue
5	U3778

site_id	FC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5159

Chain	Residue
5	A3783

site_id	GC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5160

Chain	Residue
5	A3817

site_id	GC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5161

Chain	Residue
5	A2363
5	U3853

site_id	GC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG 5 5162

Chain	Residue
5	A1324
5	C1325
5	G3875
5	A3876
5	A3877
5	G3879

site_id	GC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5163

Chain	Residue
5	C1678
5	G3913
5	U3914

site_id	GC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5164

Chain	Residue
5	U3912
5	C4193
5	U4194

site_id	GC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5165

Chain	Residue
5	G40
5	C41
5	U3915
5	G3916

site_id	GC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5166

Chain	Residue
5	A3917

site_id	GC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5168

Chain	Residue
5	U3920
5	G4184
A	PRO206

site_id	GC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5169

Chain	Residue
5	A3923
5	C3924

site_id	HC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5170

Chain	Residue
5	U35
5	U4188

site_id	HC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5171

Chain	Residue
5	G1734
5	U1735

site_id	HC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5172

Chain	Residue
5	A4214
5	C4215

site_id	HC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5173

Chain	Residue
5	G4235
5	C4332

site_id	HC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5174

Chain	Residue
5	A4239

site_id	HC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5175

Chain	Residue
5	A4281
D	TYR31

site_id	HC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5177

Chain	Residue
5	A4385

site_id	HC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5178

Chain	Residue
5	G1633
5	G1641
5	G4534

site_id	HC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG 5 5179

Chain	Residue
5	A1632
5	G1633
5	A4535
A	ALA203
A	ASN205

site_id	IC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5180

Chain	Residue
5	A4533

site_id	IC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5181

Chain	Residue
5	U1656
5	G4392
5	G4448

site_id	IC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG 5 5182

Chain	Residue
5	G4393
5	A4394
5	C4443
5	C4444
5	U4445

site_id	IC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5183

Chain	Residue
5	G1321
5	A4394
5	U4445

site_id	IC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5184

Chain	Residue
5	G4401

site_id	IC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5185

Chain	Residue
5	C4417

site_id	IC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5186

Chain	Residue
5	A1871

site_id	IC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5187

Chain	Residue
5	A3901
5	A3902
5	G4451

site_id	IC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5188

Chain	Residue
5	A3902
5	G4451

site_id	JC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5189

Chain	Residue
5	A4479
5	A4480

site_id	JC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5190

Chain	Residue
5	G2851
5	U2852

site_id	JC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5191

Chain	Residue
5	A2850
5	G2851
5	U2852
5	A4496

site_id	JC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5192

Chain	Residue
5	C3833
5	U4497

site_id	JC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5193

Chain	Residue
5	G4451
5	G4522
5	U4557

site_id	JC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5194

Chain	Residue
5	C4519
5	G4520
5	U4521

site_id	JC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5196

Chain	Residue
5	A4464

site_id	JC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5197

Chain	Residue
5	G3899
5	U4521
5	G4522
5	A4523

site_id	JC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5198

Chain	Residue
5	G1592
5	U4526

site_id	KC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5199

Chain	Residue
5	G4528
5	G4529

site_id	KC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5200

Chain	Residue
5	G3815
5	G4538

site_id	KC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5201

Chain	Residue
5	U1591
5	G1592
5	U4556

site_id	KC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5202

Chain	Residue
5	G1595

site_id	KC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5204

Chain	Residue
5	U4682

site_id	KC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5205

Chain	Residue
5	A4705

site_id	KC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5207

Chain	Residue
5	G4650
5	A4651

site_id	KC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5208

Chain	Residue
5	G4751
5	U4752
5	U4946
5	C4948

site_id	KC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5209

Chain	Residue
5	G1895

site_id	LC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5210

Chain	Residue
5	C1318
5	U1656

site_id	LC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5211

Chain	Residue
5	G1680

site_id	LC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5212

Chain	Residue
5	C1318
5	U1659

site_id	LC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5213

Chain	Residue
5	C322
5	G4355
5	G4356

site_id	LC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5214

Chain	Residue
5	U416

site_id	LC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5215

Chain	Residue
5	U354
5	A378
5	MG5216

site_id	LC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG 5 5216

Chain	Residue
5	A353
5	U354
5	A378
5	G379
5	MG5215

site_id	LC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5217

Chain	Residue
5	U380
5	G415

site_id	LC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5218

Chain	Residue
5	G1335
5	C2346

site_id	MC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5219

Chain	Residue
5	A4665
B	LYS373

site_id	MC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 7 201

Chain	Residue
7	A42

site_id	MC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 7 202

Chain	Residue
7	U53
7	A54
7	A55

site_id	MC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 7 203

Chain	Residue
7	U53
7	A55
7	G56

site_id	MC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 7 204

Chain	Residue
7	G65

site_id	MC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 7 205

Chain	Residue
5	G1895
7	A83

site_id	MC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 8 202

Chain	Residue
8	U14

site_id	MC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 8 203

Chain	Residue
8	A20

site_id	MC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 8 204

Chain	Residue
8	G151

site_id	NC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG P 201

Chain	Residue
P	TYR130

site_id	NC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG V 201

Chain	Residue
V	ASN50

site_id	NC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN j 101

Chain	Residue
j	CYS19
j	CYS22
j	CYS34
j	CYS37

site_id	NC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN m 201

Chain	Residue
m	CYS96
m	CYS99
m	CYS110
m	CYS115

site_id	NC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN o 201

Chain	Residue
o	CYS12
o	CYS15
o	CYS72
o	CYS77
o	SER79

Functional Information from PROSITE/UniProt

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
m	LYS27-ASP52

site_id	PS01257
Number of Residues	22
Details	RIBOSOMAL_L10E Ribosomal protein L10e signature. ADRlqtGMRgAFGKPqGtvARV

Chain	Residue	Details
I	ALA108-VAL129

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FgqdemiDviGvTkGKGykGvtsR

Chain	Residue	Details
B	PHE211-ARG234

site_id	PS00526
Number of Residues	20
Details	RIBOSOMAL_L19E Ribosomal protein L19e signature. QKRLaSsvlrCGkkkVWLDP

Chain	Residue	Details
R	GLN7-PRO26

site_id	PS00687
Number of Residues	8
Details	ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. GESSGKNV

Chain	Residue	Details
C	GLY15-VAL22

site_id	PS00939
Number of Residues	27
Details	RIBOSOMAL_L1E Ribosomal protein L1e signature. NttqKryAIcSALaASAlpalvmsKGH

Chain	Residue	Details
C	ASN116-HIS142

site_id	PS00709
Number of Residues	25
Details	RIBOSOMAL_L30E_1 Ribosomal protein L30e signature 1. SgkyvlGyKqtLKmiRqGkaKlVIL

Chain	Residue	Details
c	SER24-LEU48

site_id	PS00993
Number of Residues	21
Details	RIBOSOMAL_L30E_2 Ribosomal protein L30e signature 2. ELGTacGKyyrvctLaIiDpG

Chain	Residue	Details
c	GLU80-GLY100

site_id	PS01145
Number of Residues	14
Details	RIBOSOMAL_L34E Ribosomal protein L34e signature. TaSnKtrlsRTPGN

Chain	Residue	Details
g	THR15-ASN28

site_id	PS01106
Number of Residues	18
Details	RIBOSOMAL_L18E Ribosomal protein L18e signature. KrLfmSRtnRPpLSLsRM

Chain	Residue	Details
Q	LYS49-MET66

site_id	PS01194
Number of Residues	24
Details	RIBOSOMAL_L15E Ribosomal protein L15e signature. DKARrLGYkAkqGYVIYRiRVrRG

Chain	Residue	Details
N	ASP46-GLY69

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. VLqlLrLrQifNgTfvklnkasinMLriVepYI

Chain	Residue	Details
F	VAL110-ILE142

site_id	PS01077
Number of Residues	20
Details	RIBOSOMAL_L37E Ribosomal protein L37e signature. GTsSfGkRrnkt.HtlCrRCG

Chain	Residue	Details
j	GLY4-GLY23

site_id	PS01073
Number of Residues	18
Details	RIBOSOMAL_L24E Ribosomal protein L24e signature. FsGykIyPGhGrrYaRtD

Chain	Residue	Details
W	PHE8-ASP25

site_id	PS01190
Number of Residues	11
Details	RIBOSOMAL_L36E Ribosomal protein L36e signature. PYERRaMELLK

Chain	Residue	Details
i	PRO52-LYS62

site_id	PS01144
Number of Residues	15
Details	RIBOSOMAL_L31E Ribosomal protein L31e signature. VRIDtrLNkAvWaKG

Chain	Residue	Details
d	VAL62-GLY76

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVIrqrksyrrk.DGvflyFedNagVI

Chain	Residue	Details
V	ALA79-ILE105

site_id	PS01108
Number of Residues	19
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeVqVVrGhyKGqqiGkV

Chain	Residue	Details
Y	ASP52-VAL70

site_id	PS00783
Number of Residues	24
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. VRGMLPhktkrGQaaldrLkVFdG

Chain	Residue	Details
O	VAL84-GLY107

site_id	PS00475
Number of Residues	32
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KVLGkGkLpkqp.ViVkakfFSrrAeekIkgvG

Chain	Residue	Details
a	LYS110-GLY141

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LeqLTGQtpVfSkARyT

Chain	Residue	Details
J	LEU40-THR56

site_id	PS00700
Number of Residues	22
Details	RIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. QattVknKdiRkFlDGIYVseK

Chain	Residue	Details
H	GLN163-LYS184

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PrvRGVAmNPvE

Chain	Residue	Details
A	PRO197-GLU208

site_id	PS01105
Number of Residues	22
Details	RIBOSOMAL_L35AE Ribosomal protein L35Ae signature. GKVtRaHGnsGmVrAkFrsnLP

Chain	Residue	Details
f	GLY72-PRO93

site_id	PS00051
Number of Residues	17
Details	RIBOSOMAL_L39E Ribosomal protein L39e signature. KTgnkIryNskrRHWRR

Chain	Residue	Details
l	LYS30-ARG46

site_id	PS00580
Number of Residues	21
Details	RIBOSOMAL_L32E Ribosomal protein L32e signature. FiRhqsdRyvKIkrn..WRKprG

Chain	Residue	Details
e	PHE20-GLY40

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. RrrTyRAhGRinpymsspCHIEMiL

Chain	Residue	Details
P	ARG126-LEU150

site_id	PS01172
Number of Residues	12
Details	RIBOSOMAL_L44E Ribosomal protein L44e signature. KtTKKivLRleC

Chain	Residue	Details
o	LYS61-CYS72

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CrkmgVPYciIkGKarLG

Chain	Residue	Details
G	CYS174-GLY191

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVRLApdydaldV

Chain	Residue	Details
X	LYS134-VAL149

site_id	PS01107
Number of Residues	12
Details	RIBOSOMAL_L27E Ribosomal protein L27e signature. GKNkWFFqkLRF

Chain	Residue	Details
Z	GLY125-PHE136

site_id	PS01104
Number of Residues	15
Details	RIBOSOMAL_L13E Ribosomal protein L13e signature. RaGRGFSLeELrvaG

Chain	Residue	Details
L	ARG71-GLY85

site_id	PS01170
Number of Residues	19
Details	RIBOSOMAL_L6E Ribosomal protein L6e signature. NrvPLRRthqkFVIATSt.K

Chain	Residue	Details
E	ASN178-LYS196

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. KLSKIRvVRKSIARV

Chain	Residue	Details
h	LYS43-VAL57

site_id	PS01171
Number of Residues	26
Details	RIBOSOMAL_L21E Ribosomal protein L21e signature. GDiVdikgmgtvqk.GmpHkcYhGkTG

Chain	Residue	Details
T	GLY37-GLY62

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	SITE: Interacts with activating enzyme

Chain	Residue	Details
m	ARG54
m	ARG72

site_id	SWS_FT_FI2
Number of Residues	1
Details	SITE: Essential for function

Chain	Residue	Details
m	HIS68
J	THR47

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine; by PINK1 => ECO:0000250\|UniProtKB:P62987

Chain	Residue	Details
m	SER65
d	LYS70
Q	GLY171

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: ADP-ribosylglycine => ECO:0000250\|UniProtKB:P62987

Chain	Residue	Details
m	GLY76

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: N6,N6,N6-trimethyllysine => ECO:0000250\|UniProtKB:P62986

Chain	Residue	Details
m	LYS98
J	LYS154

site_id	SWS_FT_FI6
Number of Residues	6
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250\|UniProtKB:P62987

Chain	Residue	Details
m	LYS6
m	LYS11
m	LYS29
m	LYS33
m	LYS48
m	LYS63

site_id	SWS_FT_FI7
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)

Chain	Residue	Details
m	GLY76

site_id	SWS_FT_FI8
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250\|UniProtKB:P62987, ECO:0000305

Chain	Residue	Details
m	LYS27

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)