3J46
Structure of the SecY protein translocation channel in action
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| 5 | 0000027 | biological_process | ribosomal large subunit assembly |
| 5 | 0000049 | molecular_function | tRNA binding |
| 5 | 0002181 | biological_process | cytoplasmic translation |
| 5 | 0003723 | molecular_function | RNA binding |
| 5 | 0003729 | molecular_function | mRNA binding |
| 5 | 0003735 | molecular_function | structural constituent of ribosome |
| 5 | 0005515 | molecular_function | protein binding |
| 5 | 0005737 | cellular_component | cytoplasm |
| 5 | 0005829 | cellular_component | cytosol |
| 5 | 0005840 | cellular_component | ribosome |
| 5 | 0006412 | biological_process | translation |
| 5 | 0006417 | biological_process | regulation of translation |
| 5 | 0015934 | cellular_component | large ribosomal subunit |
| 5 | 0019843 | molecular_function | rRNA binding |
| 5 | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| 5 | 0045947 | biological_process | negative regulation of translational initiation |
| 5 | 1990904 | cellular_component | ribonucleoprotein complex |
| E | 0006605 | biological_process | protein targeting |
| E | 0006886 | biological_process | intracellular protein transport |
| E | 0008320 | molecular_function | protein transmembrane transporter activity |
| E | 0009306 | biological_process | protein secretion |
| E | 0016020 | cellular_component | membrane |
| G | 0009306 | biological_process | protein secretion |
| G | 0015450 | molecular_function | protein-transporting ATPase activity |
| G | 0016020 | cellular_component | membrane |
| T | 0000027 | biological_process | ribosomal large subunit assembly |
| T | 0002181 | biological_process | cytoplasmic translation |
| T | 0003723 | molecular_function | RNA binding |
| T | 0003735 | molecular_function | structural constituent of ribosome |
| T | 0005515 | molecular_function | protein binding |
| T | 0005737 | cellular_component | cytoplasm |
| T | 0005840 | cellular_component | ribosome |
| T | 0006412 | biological_process | translation |
| T | 0019843 | molecular_function | rRNA binding |
| T | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| T | 1990904 | cellular_component | ribonucleoprotein complex |
| U | 0000027 | biological_process | ribosomal large subunit assembly |
| U | 0002181 | biological_process | cytoplasmic translation |
| U | 0003723 | molecular_function | RNA binding |
| U | 0003735 | molecular_function | structural constituent of ribosome |
| U | 0005515 | molecular_function | protein binding |
| U | 0005737 | cellular_component | cytoplasm |
| U | 0005829 | cellular_component | cytosol |
| U | 0005840 | cellular_component | ribosome |
| U | 0006412 | biological_process | translation |
| U | 0019843 | molecular_function | rRNA binding |
| U | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| U | 0070180 | molecular_function | large ribosomal subunit rRNA binding |
| U | 1990904 | cellular_component | ribonucleoprotein complex |
| y | 0005048 | molecular_function | signal sequence binding |
| y | 0005515 | molecular_function | protein binding |
| y | 0005886 | cellular_component | plasma membrane |
| y | 0006605 | biological_process | protein targeting |
| y | 0006616 | biological_process | SRP-dependent cotranslational protein targeting to membrane, translocation |
| y | 0006886 | biological_process | intracellular protein transport |
| y | 0008320 | molecular_function | protein transmembrane transporter activity |
| y | 0015031 | biological_process | protein transport |
| y | 0016020 | cellular_component | membrane |
| y | 0031522 | cellular_component | cell envelope Sec protein transport complex |
| y | 0043952 | biological_process | protein transport by the Sec complex |
| y | 0065002 | biological_process | intracellular protein transmembrane transport |
| Y | 0000027 | biological_process | ribosomal large subunit assembly |
| Y | 0002181 | biological_process | cytoplasmic translation |
| Y | 0003723 | molecular_function | RNA binding |
| Y | 0003735 | molecular_function | structural constituent of ribosome |
| Y | 0005737 | cellular_component | cytoplasm |
| Y | 0005840 | cellular_component | ribosome |
| Y | 0006412 | biological_process | translation |
| Y | 0019843 | molecular_function | rRNA binding |
| Y | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| Y | 1990904 | cellular_component | ribonucleoprotein complex |
Functional Information from PROSITE/UniProt
| site_id | PS00430 |
| Number of Residues | 66 |
| Details | TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. mireerllkvlraphvsekastameksntivlkvakdatkaeikaavqklfevevevv.........................................................NTLVVKGK |
| Chain | Residue | Details |
| T | MET1-LYS66 |
| site_id | PS00579 |
| Number of Residues | 15 |
| Details | RIBOSOMAL_L29 Ribosomal protein L29 signature. QSHLLKqVRRDVARV |
| Chain | Residue | Details |
| Y | GLN39-VAL53 |
| site_id | PS01199 |
| Number of Residues | 19 |
| Details | RIBOSOMAL_L1 Ribosomal protein L1 signature. MrvVgq.LGqvLGPRGlMPN |
| Chain | Residue | Details |
| 5 | MET121-ASN139 |
| site_id | PS01108 |
| Number of Residues | 18 |
| Details | RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeViVLtGkdKGkr.GkV |
| Chain | Residue | Details |
| U | ASP7-VAL24 |
| site_id | PS00755 |
| Number of Residues | 20 |
| Details | SECY_1 Protein secY signature 1. SIFaLGImPYIsASIIIQLL |
| Chain | Residue | Details |
| y | SER76-LEU95 |
| site_id | PS00756 |
| Number of Residues | 18 |
| Details | SECY_2 Protein secY signature 2. WLgEqITer.GIGNGiSII |
| Chain | Residue | Details |
| y | TRP173-ILE190 |
| site_id | PS00050 |
| Number of Residues | 16 |
| Details | RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVTLKegqnldfV |
| Chain | Residue | Details |
| T | LYS81-VAL96 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Transmembrane: {"description":"Helical; Name=1","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Topological domain: {"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 35 |
| Details | Transmembrane: {"description":"Discontinuously helical; Name=2","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 9 |
| Details | Intramembrane: {"description":"Helical; Name=Helix 2A","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 5 |
| Details | Intramembrane: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 19 |
| Details | Intramembrane: {"description":"Helical; Name=Helix 2B","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 107 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 15 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 80 |
| Details | Topological domain: {"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 13 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 16 |
| Details | Transmembrane: {"description":"Helical; Name=5","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 13 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 13 |
| Details | Transmembrane: {"description":"Helical; Name=7","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 15 |
| Details | Transmembrane: {"description":"Helical; Name=8","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 14 |
| Details | Transmembrane: {"description":"Helical; Name=9","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 16 |
| Details | Transmembrane: {"description":"Helical; Name=10","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 43 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI18 |
| Number of Residues | 24 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"15919996","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI19 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"PubMed","id":"21151122","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
