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3J0P

Core of mammalian 80S pre-ribosome in complex with tRNAs fitted to a 10.6A cryo-em map: rotated PRE state 1

Functional Information from GO Data
ChainGOidnamespacecontents
B0000055biological_processribosomal large subunit export from nucleus
B0002181biological_processcytoplasmic translation
B0003723molecular_functionRNA binding
B0003735molecular_functionstructural constituent of ribosome
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005840cellular_componentribosome
B0006412biological_processtranslation
B0015934cellular_componentlarge ribosomal subunit
B0022625cellular_componentcytosolic large ribosomal subunit
B1990904cellular_componentribonucleoprotein complex
L0003735molecular_functionstructural constituent of ribosome
L0005840cellular_componentribosome
L0006412biological_processtranslation
L0015935cellular_componentsmall ribosomal subunit
S0003723molecular_functionRNA binding
S0003735molecular_functionstructural constituent of ribosome
S0005840cellular_componentribosome
S0006412biological_processtranslation
X0003735molecular_functionstructural constituent of ribosome
X0005840cellular_componentribosome
X0006412biological_processtranslation
Functional Information from PROSITE/UniProt
site_idPS00055
Number of Residues8
DetailsRIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAvR
ChainResidueDetails
LLYS61-ARG68

site_idPS00323
Number of Residues25
DetailsRIBOSOMAL_S19 Ribosomal protein S19 signature. NGKefvnveVkfdmIGkyLAEFamT
ChainResidueDetails
SASN103-THR127

site_idPS01199
Number of Residues20
DetailsRIBOSOMAL_L1 Ribosomal protein L1 signature. IkqVprlLGpqLSKAGkFPT
ChainResidueDetails
BILE117-THR136

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsModified residue: {"description":"N6-methyllysine; by RKM5","evidences":[{"source":"PubMed","id":"21460220","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues1
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues1
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

239492

PDB entries from 2025-07-30

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