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3IT8

Crystal structure of TNF alpha complexed with a poxvirus MHC-related TNF binding protein

Functional Information from GO Data
ChainGOidnamespacecontents
A0005164molecular_functiontumor necrosis factor receptor binding
A0006955biological_processimmune response
A0016020cellular_componentmembrane
B0005164molecular_functiontumor necrosis factor receptor binding
B0006955biological_processimmune response
B0016020cellular_componentmembrane
C0005164molecular_functiontumor necrosis factor receptor binding
C0006955biological_processimmune response
C0016020cellular_componentmembrane
D0005515molecular_functionprotein binding
E0005515molecular_functionprotein binding
F0005515molecular_functionprotein binding
G0005164molecular_functiontumor necrosis factor receptor binding
G0006955biological_processimmune response
G0016020cellular_componentmembrane
H0005164molecular_functiontumor necrosis factor receptor binding
H0006955biological_processimmune response
H0016020cellular_componentmembrane
I0005164molecular_functiontumor necrosis factor receptor binding
I0006955biological_processimmune response
I0016020cellular_componentmembrane
J0005515molecular_functionprotein binding
K0005515molecular_functionprotein binding
L0005515molecular_functionprotein binding
Functional Information from PROSITE/UniProt
site_idPS00251
Number of Residues17
DetailsTHD_1 Tumor necrosis factor (TNF) homology domain (THD) signature. LvVPsEGLYLIysQVlF
ChainResidueDetails
ALEU48-PHE64

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues870
DetailsDomain: {"description":"THD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01387","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

249697

PDB entries from 2026-02-25

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