3IT8

Crystal structure of TNF alpha complexed with a poxvirus MHC-related TNF binding protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005164	molecular_function	tumor necrosis factor receptor binding
A	0006955	biological_process	immune response
A	0016020	cellular_component	membrane
B	0005164	molecular_function	tumor necrosis factor receptor binding
B	0006955	biological_process	immune response
B	0016020	cellular_component	membrane
C	0005164	molecular_function	tumor necrosis factor receptor binding
C	0006955	biological_process	immune response
C	0016020	cellular_component	membrane
D	0004674	molecular_function	protein serine/threonine kinase activity
D	0005515	molecular_function	protein binding
D	0006508	biological_process	proteolysis
D	0008233	molecular_function	peptidase activity
E	0004674	molecular_function	protein serine/threonine kinase activity
E	0005515	molecular_function	protein binding
E	0006508	biological_process	proteolysis
E	0008233	molecular_function	peptidase activity
F	0004674	molecular_function	protein serine/threonine kinase activity
F	0005515	molecular_function	protein binding
F	0006508	biological_process	proteolysis
F	0008233	molecular_function	peptidase activity
G	0005164	molecular_function	tumor necrosis factor receptor binding
G	0006955	biological_process	immune response
G	0016020	cellular_component	membrane
H	0005164	molecular_function	tumor necrosis factor receptor binding
H	0006955	biological_process	immune response
H	0016020	cellular_component	membrane
I	0005164	molecular_function	tumor necrosis factor receptor binding
I	0006955	biological_process	immune response
I	0016020	cellular_component	membrane
J	0004674	molecular_function	protein serine/threonine kinase activity
J	0005515	molecular_function	protein binding
J	0006508	biological_process	proteolysis
J	0008233	molecular_function	peptidase activity
K	0004674	molecular_function	protein serine/threonine kinase activity
K	0005515	molecular_function	protein binding
K	0006508	biological_process	proteolysis
K	0008233	molecular_function	peptidase activity
L	0004674	molecular_function	protein serine/threonine kinase activity
L	0005515	molecular_function	protein binding
L	0006508	biological_process	proteolysis
L	0008233	molecular_function	peptidase activity

Functional Information from PROSITE/UniProt

site_id	PS00251
Number of Residues	17
Details	THD_1 Tumor necrosis factor (TNF) homology domain (THD) signature. LvVPsEGLYLIysQVlF

Chain	Residue	Details
A	LEU48-PHE64

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	870
Details	Domain: {"description":"THD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01387","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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