3ISZ
Crystal structure of mono-zinc form of succinyl-diaminopimelate desuccinylase from Haemophilus influenzae
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009014 | molecular_function | succinyl-diaminopimelate desuccinylase activity |
| A | 0009085 | biological_process | lysine biosynthetic process |
| A | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019877 | biological_process | diaminopimelate biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050897 | molecular_function | cobalt ion binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009014 | molecular_function | succinyl-diaminopimelate desuccinylase activity |
| B | 0009085 | biological_process | lysine biosynthetic process |
| B | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0019877 | biological_process | diaminopimelate biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0050897 | molecular_function | cobalt ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1001 |
| Chain | Residue |
| A | HIS67 |
| A | ASP100 |
| A | GLU163 |
| A | HOH572 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 378 |
| Chain | Residue |
| A | HOH587 |
| A | HOH588 |
| A | ARG178 |
| A | ARG179 |
| A | GLY322 |
| A | HOH552 |
| A | HOH580 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1001 |
| Chain | Residue |
| B | HIS67 |
| B | ASP100 |
| B | GLU163 |
| B | HOH420 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 378 |
| Chain | Residue |
| B | ARG178 |
| B | ARG179 |
| B | ARG258 |
| B | GLY322 |
| B | HOH419 |
| B | HOH491 |
Functional Information from PROSITE/UniProt
| site_id | PS00758 |
| Number of Residues | 10 |
| Details | ARGE_DAPE_CPG2_1 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. IAFAGHtDVV |
| Chain | Residue | Details |
| A | ILE62-VAL71 |
| site_id | PS00759 |
| Number of Residues | 40 |
| Details | ARGE_DAPE_CPG2_2 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. AADmKGslAamIvaaeeyvkanpnhkgt.IaLLItsDEEaT |
| Chain | Residue | Details |
| A | ALA98-THR137 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000305|PubMed:20138056 |
| Chain | Residue | Details |
| A | ASP69 | |
| B | ASP69 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000269|PubMed:20138056 |
| Chain | Residue | Details |
| A | GLU134 | |
| B | GLU134 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20138056, ECO:0007744|PDB:3IC1, ECO:0007744|PDB:3ISZ, ECO:0007744|PDB:4H2K |
| Chain | Residue | Details |
| A | HIS67 | |
| A | GLU163 | |
| B | HIS67 | |
| B | GLU163 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20138056, ECO:0007744|PDB:3IC1, ECO:0007744|PDB:4H2K |
| Chain | Residue | Details |
| A | ASP100 | |
| A | GLU135 | |
| A | HIS349 | |
| B | ASP100 | |
| B | GLU135 | |
| B | HIS349 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1amp |
| Chain | Residue | Details |
| A | GLU134 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1amp |
| Chain | Residue | Details |
| B | GLU134 |
| site_id | CSA3 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1amp |
| Chain | Residue | Details |
| A | GLU135 | |
| A | ASP100 | |
| A | HIS349 | |
| A | GLU134 | |
| A | HIS67 | |
| A | GLU163 |
| site_id | CSA4 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1amp |
| Chain | Residue | Details |
| B | GLU135 | |
| B | ASP100 | |
| B | HIS349 | |
| B | GLU134 | |
| B | HIS67 | |
| B | GLU163 |
