3IQZ
Structure of F420 dependent methylene-tetrahydromethanopterin dehydrogenase in complex with methylene-tetrahydromethanopterin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006730 | biological_process | one-carbon metabolic process |
| A | 0008901 | molecular_function | ferredoxin hydrogenase activity |
| A | 0015948 | biological_process | methanogenesis |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019386 | biological_process | methanogenesis, from carbon dioxide |
| A | 0030268 | molecular_function | methylenetetrahydromethanopterin dehydrogenase activity |
| B | 0006730 | biological_process | one-carbon metabolic process |
| B | 0008901 | molecular_function | ferredoxin hydrogenase activity |
| B | 0015948 | biological_process | methanogenesis |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019386 | biological_process | methanogenesis, from carbon dioxide |
| B | 0030268 | molecular_function | methylenetetrahydromethanopterin dehydrogenase activity |
| C | 0006730 | biological_process | one-carbon metabolic process |
| C | 0008901 | molecular_function | ferredoxin hydrogenase activity |
| C | 0015948 | biological_process | methanogenesis |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0019386 | biological_process | methanogenesis, from carbon dioxide |
| C | 0030268 | molecular_function | methylenetetrahydromethanopterin dehydrogenase activity |
| D | 0006730 | biological_process | one-carbon metabolic process |
| D | 0008901 | molecular_function | ferredoxin hydrogenase activity |
| D | 0015948 | biological_process | methanogenesis |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0019386 | biological_process | methanogenesis, from carbon dioxide |
| D | 0030268 | molecular_function | methylenetetrahydromethanopterin dehydrogenase activity |
| E | 0006730 | biological_process | one-carbon metabolic process |
| E | 0008901 | molecular_function | ferredoxin hydrogenase activity |
| E | 0015948 | biological_process | methanogenesis |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0019386 | biological_process | methanogenesis, from carbon dioxide |
| E | 0030268 | molecular_function | methylenetetrahydromethanopterin dehydrogenase activity |
| F | 0006730 | biological_process | one-carbon metabolic process |
| F | 0008901 | molecular_function | ferredoxin hydrogenase activity |
| F | 0015948 | biological_process | methanogenesis |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0019386 | biological_process | methanogenesis, from carbon dioxide |
| F | 0030268 | molecular_function | methylenetetrahydromethanopterin dehydrogenase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE H4M A 284 |
| Chain | Residue |
| A | ASN13 |
| A | ASN141 |
| A | CYS221 |
| A | TYR230 |
| A | HOH313 |
| D | GLU26 |
| D | ARG27 |
| A | GLY15 |
| A | MET124 |
| A | LEU125 |
| A | ALA127 |
| A | ARG128 |
| A | ARG129 |
| A | GLU130 |
| A | MET137 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE H4M B 284 |
| Chain | Residue |
| B | ASN13 |
| B | LEU14 |
| B | GLY15 |
| B | VAL42 |
| B | MET124 |
| B | LEU125 |
| B | ALA127 |
| B | ARG128 |
| B | ARG129 |
| B | GLU130 |
| B | ASN141 |
| B | LEU144 |
| B | CYS221 |
| B | TYR230 |
| B | HOH293 |
| B | HOH299 |
| B | HOH310 |
| F | GLU26 |
| F | ARG27 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA B 285 |
| Chain | Residue |
| B | GLU85 |
| B | ASP89 |
| E | GLU47 |
| E | GLU50 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 286 |
| Chain | Residue |
| B | GLU111 |
| B | GLN112 |
| B | GLU175 |
| B | HOH336 |
| B | HOH365 |
| site_id | AC5 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE H4M C 284 |
| Chain | Residue |
| C | ASN13 |
| C | GLY15 |
| C | MET124 |
| C | LEU125 |
| C | ALA127 |
| C | ARG128 |
| C | ARG129 |
| C | GLU130 |
| C | MET137 |
| C | ASN141 |
| C | LEU144 |
| C | CYS221 |
| C | TYR230 |
| C | HOH286 |
| C | HOH305 |
| C | HOH325 |
| C | HOH338 |
| E | GLU26 |
| E | ARG27 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE H4M D 284 |
| Chain | Residue |
| A | GLU26 |
| A | ARG27 |
| D | ASN13 |
| D | GLY15 |
| D | MET124 |
| D | LEU125 |
| D | ALA127 |
| D | ARG128 |
| D | ARG129 |
| D | GLU130 |
| D | ASN141 |
| D | LEU144 |
| D | CYS221 |
| D | TYR230 |
| D | HOH286 |
| D | HOH293 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA D 285 |
| Chain | Residue |
| A | LYS256 |
| A | ARG263 |
| B | TYR198 |
| D | PHE131 |
| D | GLU136 |
| D | HOH290 |
| site_id | AC8 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE H4M E 284 |
| Chain | Residue |
| E | HOH288 |
| E | HOH303 |
| E | HOH326 |
| C | GLU26 |
| C | ARG27 |
| C | HOH337 |
| E | ASN13 |
| E | GLY15 |
| E | MET124 |
| E | LEU125 |
| E | ALA127 |
| E | ARG128 |
| E | ARG129 |
| E | GLU130 |
| E | ASN141 |
| E | LEU144 |
| E | CYS221 |
| E | TYR230 |
| site_id | AC9 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE H4M F 284 |
| Chain | Residue |
| B | GLU26 |
| B | ARG27 |
| F | ASN13 |
| F | GLY15 |
| F | MET124 |
| F | LEU125 |
| F | ALA127 |
| F | ARG128 |
| F | ARG129 |
| F | GLU130 |
| F | ASN141 |
| F | LEU144 |
| F | CYS221 |
| F | TYR230 |
| F | HOH297 |
| F | HOH312 |
| F | HOH316 |
| F | HOH333 |
| site_id | BC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NA F 285 |
| Chain | Residue |
| F | ARG129 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 168 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
