Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3IPM

Crystal Structure of Archaeal 20S Proteasome in Complex with the C-terminus of PAN

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000502	cellular_component	proteasome complex
A	0004175	molecular_function	endopeptidase activity
A	0004298	molecular_function	threonine-type endopeptidase activity
A	0005737	cellular_component	cytoplasm
A	0005839	cellular_component	proteasome core complex
A	0006511	biological_process	ubiquitin-dependent protein catabolic process
A	0010498	biological_process	proteasomal protein catabolic process
A	0019773	cellular_component	proteasome core complex, alpha-subunit complex
A	0051603	biological_process	proteolysis involved in protein catabolic process
B	0000502	cellular_component	proteasome complex
B	0004175	molecular_function	endopeptidase activity
B	0004298	molecular_function	threonine-type endopeptidase activity
B	0005737	cellular_component	cytoplasm
B	0005839	cellular_component	proteasome core complex
B	0006511	biological_process	ubiquitin-dependent protein catabolic process
B	0010498	biological_process	proteasomal protein catabolic process
B	0019773	cellular_component	proteasome core complex, alpha-subunit complex
B	0051603	biological_process	proteolysis involved in protein catabolic process
C	0000502	cellular_component	proteasome complex
C	0004175	molecular_function	endopeptidase activity
C	0004298	molecular_function	threonine-type endopeptidase activity
C	0005737	cellular_component	cytoplasm
C	0005839	cellular_component	proteasome core complex
C	0006511	biological_process	ubiquitin-dependent protein catabolic process
C	0010498	biological_process	proteasomal protein catabolic process
C	0019773	cellular_component	proteasome core complex, alpha-subunit complex
C	0051603	biological_process	proteolysis involved in protein catabolic process
D	0000502	cellular_component	proteasome complex
D	0004175	molecular_function	endopeptidase activity
D	0004298	molecular_function	threonine-type endopeptidase activity
D	0005737	cellular_component	cytoplasm
D	0005839	cellular_component	proteasome core complex
D	0006511	biological_process	ubiquitin-dependent protein catabolic process
D	0010498	biological_process	proteasomal protein catabolic process
D	0019773	cellular_component	proteasome core complex, alpha-subunit complex
D	0051603	biological_process	proteolysis involved in protein catabolic process
E	0000502	cellular_component	proteasome complex
E	0004175	molecular_function	endopeptidase activity
E	0004298	molecular_function	threonine-type endopeptidase activity
E	0005737	cellular_component	cytoplasm
E	0005839	cellular_component	proteasome core complex
E	0006511	biological_process	ubiquitin-dependent protein catabolic process
E	0010498	biological_process	proteasomal protein catabolic process
E	0019773	cellular_component	proteasome core complex, alpha-subunit complex
E	0051603	biological_process	proteolysis involved in protein catabolic process
F	0000502	cellular_component	proteasome complex
F	0004175	molecular_function	endopeptidase activity
F	0004298	molecular_function	threonine-type endopeptidase activity
F	0005737	cellular_component	cytoplasm
F	0005839	cellular_component	proteasome core complex
F	0006511	biological_process	ubiquitin-dependent protein catabolic process
F	0010498	biological_process	proteasomal protein catabolic process
F	0019773	cellular_component	proteasome core complex, alpha-subunit complex
F	0051603	biological_process	proteolysis involved in protein catabolic process
G	0000502	cellular_component	proteasome complex
G	0004175	molecular_function	endopeptidase activity
G	0004298	molecular_function	threonine-type endopeptidase activity
G	0005737	cellular_component	cytoplasm
G	0005839	cellular_component	proteasome core complex
G	0006511	biological_process	ubiquitin-dependent protein catabolic process
G	0010498	biological_process	proteasomal protein catabolic process
G	0019773	cellular_component	proteasome core complex, alpha-subunit complex
G	0051603	biological_process	proteolysis involved in protein catabolic process
H	0000502	cellular_component	proteasome complex
H	0004175	molecular_function	endopeptidase activity
H	0004298	molecular_function	threonine-type endopeptidase activity
H	0005737	cellular_component	cytoplasm
H	0005839	cellular_component	proteasome core complex
H	0006508	biological_process	proteolysis
H	0010498	biological_process	proteasomal protein catabolic process
H	0019774	cellular_component	proteasome core complex, beta-subunit complex
H	0051603	biological_process	proteolysis involved in protein catabolic process
I	0000502	cellular_component	proteasome complex
I	0004175	molecular_function	endopeptidase activity
I	0004298	molecular_function	threonine-type endopeptidase activity
I	0005737	cellular_component	cytoplasm
I	0005839	cellular_component	proteasome core complex
I	0006508	biological_process	proteolysis
I	0010498	biological_process	proteasomal protein catabolic process
I	0019774	cellular_component	proteasome core complex, beta-subunit complex
I	0051603	biological_process	proteolysis involved in protein catabolic process
J	0000502	cellular_component	proteasome complex
J	0004175	molecular_function	endopeptidase activity
J	0004298	molecular_function	threonine-type endopeptidase activity
J	0005737	cellular_component	cytoplasm
J	0005839	cellular_component	proteasome core complex
J	0006508	biological_process	proteolysis
J	0010498	biological_process	proteasomal protein catabolic process
J	0019774	cellular_component	proteasome core complex, beta-subunit complex
J	0051603	biological_process	proteolysis involved in protein catabolic process
K	0000502	cellular_component	proteasome complex
K	0004175	molecular_function	endopeptidase activity
K	0004298	molecular_function	threonine-type endopeptidase activity
K	0005737	cellular_component	cytoplasm
K	0005839	cellular_component	proteasome core complex
K	0006508	biological_process	proteolysis
K	0010498	biological_process	proteasomal protein catabolic process
K	0019774	cellular_component	proteasome core complex, beta-subunit complex
K	0051603	biological_process	proteolysis involved in protein catabolic process
L	0000502	cellular_component	proteasome complex
L	0004175	molecular_function	endopeptidase activity
L	0004298	molecular_function	threonine-type endopeptidase activity
L	0005737	cellular_component	cytoplasm
L	0005839	cellular_component	proteasome core complex
L	0006508	biological_process	proteolysis
L	0010498	biological_process	proteasomal protein catabolic process
L	0019774	cellular_component	proteasome core complex, beta-subunit complex
L	0051603	biological_process	proteolysis involved in protein catabolic process
M	0000502	cellular_component	proteasome complex
M	0004175	molecular_function	endopeptidase activity
M	0004298	molecular_function	threonine-type endopeptidase activity
M	0005737	cellular_component	cytoplasm
M	0005839	cellular_component	proteasome core complex
M	0006508	biological_process	proteolysis
M	0010498	biological_process	proteasomal protein catabolic process
M	0019774	cellular_component	proteasome core complex, beta-subunit complex
M	0051603	biological_process	proteolysis involved in protein catabolic process
N	0000502	cellular_component	proteasome complex
N	0004175	molecular_function	endopeptidase activity
N	0004298	molecular_function	threonine-type endopeptidase activity
N	0005737	cellular_component	cytoplasm
N	0005839	cellular_component	proteasome core complex
N	0006508	biological_process	proteolysis
N	0010498	biological_process	proteasomal protein catabolic process
N	0019774	cellular_component	proteasome core complex, beta-subunit complex
N	0051603	biological_process	proteolysis involved in protein catabolic process
O	0000502	cellular_component	proteasome complex
O	0006508	biological_process	proteolysis
O	0008537	cellular_component	proteasome activator complex
O	0061136	biological_process	regulation of proteasomal protein catabolic process
P	0000502	cellular_component	proteasome complex
P	0006508	biological_process	proteolysis
P	0008537	cellular_component	proteasome activator complex
P	0061136	biological_process	regulation of proteasomal protein catabolic process
Q	0000502	cellular_component	proteasome complex
Q	0006508	biological_process	proteolysis
Q	0008537	cellular_component	proteasome activator complex
Q	0061136	biological_process	regulation of proteasomal protein catabolic process
R	0000502	cellular_component	proteasome complex
R	0006508	biological_process	proteolysis
R	0008537	cellular_component	proteasome activator complex
R	0061136	biological_process	regulation of proteasomal protein catabolic process
S	0000502	cellular_component	proteasome complex
S	0006508	biological_process	proteolysis
S	0008537	cellular_component	proteasome activator complex
S	0061136	biological_process	regulation of proteasomal protein catabolic process
T	0000502	cellular_component	proteasome complex
T	0006508	biological_process	proteolysis
T	0008537	cellular_component	proteasome activator complex
T	0061136	biological_process	regulation of proteasomal protein catabolic process
U	0000502	cellular_component	proteasome complex
U	0006508	biological_process	proteolysis
U	0008537	cellular_component	proteasome activator complex
U	0061136	biological_process	regulation of proteasomal protein catabolic process

Functional Information from PROSITE/UniProt

site_id	PS00388
Number of Residues	23
Details	PROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. YdraiTvFSPdGRlfQVEYAreA

Chain	Residue	Details
A	TYR8-ALA30

site_id	PS00854
Number of Residues	48
Details	PROTEASOME_BETA_1 Proteasome beta-type subunits signature. VGItLkdAVIMATErrvtmenfimhkngk.KlfqidtytgmtiaGlvGD

Chain	Residue	Details
H	VAL4-ASP51

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	ACT_SITE: Nucleophile => ECO:0000255\|HAMAP-Rule:MF_02113, ECO:0000269\|PubMed:7725107

Chain	Residue	Details
H	THR1
I	THR1
J	THR1
K	THR1
L	THR1
M	THR1
N	THR1

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1pma

Chain	Residue	Details
H	GLY47
H	LYS33
H	THR1
H	SER129

site_id	CSA10
Number of Residues	4
Details	Annotated By Reference To The Literature 1pma

Chain	Residue	Details
C	GLY80
C	SER35
C	SER167
C	LYS66

site_id	CSA11
Number of Residues	4
Details	Annotated By Reference To The Literature 1pma

Chain	Residue	Details
D	GLY80
D	SER35
D	SER167
D	LYS66

site_id	CSA12
Number of Residues	4
Details	Annotated By Reference To The Literature 1pma

Chain	Residue	Details
E	GLY80
E	SER35
E	SER167
E	LYS66

site_id	CSA13
Number of Residues	4
Details	Annotated By Reference To The Literature 1pma

Chain	Residue	Details
F	GLY80
F	SER35
F	SER167
F	LYS66

site_id	CSA14
Number of Residues	4
Details	Annotated By Reference To The Literature 1pma

Chain	Residue	Details
G	GLY80
G	SER35
G	SER167
G	LYS66

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1pma

Chain	Residue	Details
I	GLY47
I	LYS33
I	THR1
I	SER129

site_id	CSA3
Number of Residues	4
Details	Annotated By Reference To The Literature 1pma

Chain	Residue	Details
J	GLY47
J	LYS33
J	THR1
J	SER129

site_id	CSA4
Number of Residues	4
Details	Annotated By Reference To The Literature 1pma

Chain	Residue	Details
K	GLY47
K	LYS33
K	THR1
K	SER129

site_id	CSA5
Number of Residues	4
Details	Annotated By Reference To The Literature 1pma

Chain	Residue	Details
L	GLY47
L	LYS33
L	THR1
L	SER129

site_id	CSA6
Number of Residues	4
Details	Annotated By Reference To The Literature 1pma

Chain	Residue	Details
M	GLY47
M	LYS33
M	THR1
M	SER129

site_id	CSA7
Number of Residues	4
Details	Annotated By Reference To The Literature 1pma

Chain	Residue	Details
N	GLY47
N	LYS33
N	THR1
N	SER129

site_id	CSA8
Number of Residues	4
Details	Annotated By Reference To The Literature 1pma

Chain	Residue	Details
A	GLY80
A	SER35
A	SER167
A	LYS66

site_id	CSA9
Number of Residues	4
Details	Annotated By Reference To The Literature 1pma

Chain	Residue	Details
B	GLY80
B	SER35
B	SER167
B	LYS66

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)