3IOT

Huntingtin amino-terminal region with 17 Gln residues - crystal C92-b

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0006974	biological_process	DNA damage response
A	0008643	biological_process	carbohydrate transport
A	0015144	molecular_function	carbohydrate transmembrane transporter activity
A	0015768	biological_process	maltose transport
A	0016020	cellular_component	membrane
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0034219	biological_process	carbohydrate transmembrane transport
A	0034289	biological_process	detection of maltose stimulus
A	0042597	cellular_component	periplasmic space
A	0042956	biological_process	maltodextrin transmembrane transport
A	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
A	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
A	0055085	biological_process	transmembrane transport
A	0060326	biological_process	cell chemotaxis
A	1901982	molecular_function	maltose binding
B	0005515	molecular_function	protein binding
B	0006974	biological_process	DNA damage response
B	0008643	biological_process	carbohydrate transport
B	0015144	molecular_function	carbohydrate transmembrane transporter activity
B	0015768	biological_process	maltose transport
B	0016020	cellular_component	membrane
B	0030288	cellular_component	outer membrane-bounded periplasmic space
B	0034219	biological_process	carbohydrate transmembrane transport
B	0034289	biological_process	detection of maltose stimulus
B	0042597	cellular_component	periplasmic space
B	0042956	biological_process	maltodextrin transmembrane transport
B	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
B	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
B	0055085	biological_process	transmembrane transport
B	0060326	biological_process	cell chemotaxis
B	1901982	molecular_function	maltose binding
C	0005515	molecular_function	protein binding
C	0006974	biological_process	DNA damage response
C	0008643	biological_process	carbohydrate transport
C	0015144	molecular_function	carbohydrate transmembrane transporter activity
C	0015768	biological_process	maltose transport
C	0016020	cellular_component	membrane
C	0030288	cellular_component	outer membrane-bounded periplasmic space
C	0034219	biological_process	carbohydrate transmembrane transport
C	0034289	biological_process	detection of maltose stimulus
C	0042597	cellular_component	periplasmic space
C	0042956	biological_process	maltodextrin transmembrane transport
C	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
C	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
C	0055085	biological_process	transmembrane transport
C	0060326	biological_process	cell chemotaxis
C	1901982	molecular_function	maltose binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN A 501

Chain	Residue
A	HIS39
C	GLU138

---

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ZN B 501

Chain	Residue
B	HIS203

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 502

Chain	Residue
A	GLU138
B	HIS39
B	ZN503

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN C 501

Chain	Residue
C	GLU291
C	GLU310

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN A 503

Chain	Residue
A	HIS203
A	ASN201

---

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN B 502

Chain	Residue
B	GLU288
B	GLU291

---

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN C 502

Chain	Residue
C	ASN201
C	HIS203

---

site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ZN C 503

Chain	Residue
C	HIS39

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN B 503

Chain	Residue
A	GLU138
A	ZN502
B	HIS39

---

site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CA C 504

Chain	Residue
C	LYS256

---

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 504

Chain	Residue
A	ASP82
A	ALA84
A	PHE85
A	GLU288
A	CA508

---

site_id	BC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CA C 505

Chain	Residue
C	ASP82

---

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CA B 504

Chain	Residue
B	ASP82

---

site_id	BC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CA A 505

Chain	Residue
A	LYS26
A	ASP30

---

site_id	BC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CA A 507

Chain	Residue
A	GLN325

---

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 508

Chain	Residue
A	ASP82
A	ALA84
A	GLU288
A	CA504

---

Functional Information from PROSITE/UniProt

site_id	PS01037
Number of Residues	18
Details	SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN

Chain	Residue	Details
A	PRO107-ASN124

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	30
Details	Region: {"description":"Sufficient for interaction with TPR","evidences":[{"source":"PubMed","id":"15654337","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"21685499","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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