3IID
Crystal structure of the macro domain of human histone macroH2A1.1 in complex with ADP-ribose (form A)
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE APR A 400 |
| Chain | Residue |
| A | ASP203 |
| A | VAL226 |
| A | THR229 |
| A | LYS236 |
| A | SER275 |
| A | SER310 |
| A | GLY312 |
| A | SER313 |
| A | GLY314 |
| A | ARG315 |
| A | ASN316 |
| A | ILE204 |
| A | PHE351 |
| A | ASP352 |
| A | HOH506 |
| A | HOH510 |
| A | HOH534 |
| A | PRO215 |
| A | THR216 |
| A | ASN217 |
| A | TYR221 |
| A | GLY223 |
| A | GLY224 |
| A | GLU225 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NO3 A 401 |
| Chain | Residue |
| A | THR188 |
| A | LYS189 |
| A | LYS196 |
| A | LYS292 |
| A | TYR334 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:A0A0D2UG83 |
| Chain | Residue | Details |
| A | ASP203 | |
| A | ILE204 | |
| A | VAL226 | |
| A | SER275 | |
| A | GLY312 | |
| A | SER313 | |
| A | GLY314 | |
| A | ASN316 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER170 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER173 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | THR178 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS167 | |
| A | LYS189 | |
| A | LYS320 |
