Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3ICE

Rho transcription termination factor bound to RNA and ADP-BeF3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003676	molecular_function	nucleic acid binding
A	0003723	molecular_function	RNA binding
A	0004386	molecular_function	helicase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0006351	biological_process	DNA-templated transcription
A	0006353	biological_process	DNA-templated transcription termination
A	0008186	molecular_function	ATP-dependent activity, acting on RNA
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0042802	molecular_function	identical protein binding
B	0000166	molecular_function	nucleotide binding
B	0003676	molecular_function	nucleic acid binding
B	0003723	molecular_function	RNA binding
B	0004386	molecular_function	helicase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005829	cellular_component	cytosol
B	0006351	biological_process	DNA-templated transcription
B	0006353	biological_process	DNA-templated transcription termination
B	0008186	molecular_function	ATP-dependent activity, acting on RNA
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0042802	molecular_function	identical protein binding
C	0000166	molecular_function	nucleotide binding
C	0003676	molecular_function	nucleic acid binding
C	0003723	molecular_function	RNA binding
C	0004386	molecular_function	helicase activity
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005829	cellular_component	cytosol
C	0006351	biological_process	DNA-templated transcription
C	0006353	biological_process	DNA-templated transcription termination
C	0008186	molecular_function	ATP-dependent activity, acting on RNA
C	0016020	cellular_component	membrane
C	0016787	molecular_function	hydrolase activity
C	0042802	molecular_function	identical protein binding
D	0000166	molecular_function	nucleotide binding
D	0003676	molecular_function	nucleic acid binding
D	0003723	molecular_function	RNA binding
D	0004386	molecular_function	helicase activity
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005829	cellular_component	cytosol
D	0006351	biological_process	DNA-templated transcription
D	0006353	biological_process	DNA-templated transcription termination
D	0008186	molecular_function	ATP-dependent activity, acting on RNA
D	0016020	cellular_component	membrane
D	0016787	molecular_function	hydrolase activity
D	0042802	molecular_function	identical protein binding
E	0000166	molecular_function	nucleotide binding
E	0003676	molecular_function	nucleic acid binding
E	0003723	molecular_function	RNA binding
E	0004386	molecular_function	helicase activity
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005829	cellular_component	cytosol
E	0006351	biological_process	DNA-templated transcription
E	0006353	biological_process	DNA-templated transcription termination
E	0008186	molecular_function	ATP-dependent activity, acting on RNA
E	0016020	cellular_component	membrane
E	0016787	molecular_function	hydrolase activity
E	0042802	molecular_function	identical protein binding
F	0000166	molecular_function	nucleotide binding
F	0003676	molecular_function	nucleic acid binding
F	0003723	molecular_function	RNA binding
F	0004386	molecular_function	helicase activity
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005829	cellular_component	cytosol
F	0006351	biological_process	DNA-templated transcription
F	0006353	biological_process	DNA-templated transcription termination
F	0008186	molecular_function	ATP-dependent activity, acting on RNA
F	0016020	cellular_component	membrane
F	0016787	molecular_function	hydrolase activity
F	0042802	molecular_function	identical protein binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE ADP A 1000

Chain	Residue
A	PRO180
A	BEF1002
B	ARG366
B	LYS367
A	LYS181
A	ALA182
A	GLY183
A	LYS184
A	THR185
A	MSE186
A	PHE355
A	MG1001

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 1001

Chain	Residue
A	THR185
A	GLU211
A	ADP1000
A	BEF1002

site_id	AC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE BEF A 1002

Chain	Residue
A	PRO180
A	LYS184
A	GLU211
A	ARG212
A	ADP1000
A	MG1001
B	LYS336
B	GLY337
B	ARG366

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE BEF F 1002

Chain	Residue
A	GLY337
A	ARG366
F	LYS184
F	GLU211
F	ADP1000
F	MG1001

site_id	AC5
Number of Residues	12
Details	BINDING SITE FOR RESIDUE ADP B 1000

Chain	Residue
B	PRO180
B	LYS181
B	ALA182
B	GLY183
B	LYS184
B	THR185
B	MSE186
B	PHE355
B	MG1001
B	BEF1002
C	ARG366
C	LYS367

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 1001

Chain	Residue
B	THR185
B	GLU211
B	ADP1000
B	BEF1002

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE BEF B 1002

Chain	Residue
B	PRO180
B	LYS184
B	GLU211
B	ARG212
B	ADP1000
B	MG1001
C	GLY337
C	ARG366

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE BEF C 1002

Chain	Residue
C	PRO180
C	LYS184
C	ARG212
C	ADP1000
C	MG1001
D	LYS336
D	GLY337
D	ARG366

site_id	AC9
Number of Residues	10
Details	BINDING SITE FOR RESIDUE ADP C 1000

Chain	Residue
C	LYS181
C	ALA182
C	GLY183
C	LYS184
C	THR185
C	MSE186
C	MG1001
C	BEF1002
D	ARG366
D	LYS367

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 1001

Chain	Residue
C	THR185
C	ARG212
C	ADP1000
C	BEF1002

site_id	BC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE ADP D 1000

Chain	Residue
D	PRO180
D	LYS181
D	ALA182
D	GLY183
D	LYS184
D	THR185
D	MSE186
D	PHE355
D	MG1001
D	BEF1002
E	ARG366
E	LYS367

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 1001

Chain	Residue
D	THR185
D	GLU211
D	ADP1000
D	BEF1002

site_id	BC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE BEF D 1002

Chain	Residue
D	ADP1000
D	MG1001
E	GLY337
E	ARG366
D	PRO180
D	LYS181
D	LYS184
D	GLU211
D	ARG212
D	LEU320

site_id	BC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE ADP E 1000

Chain	Residue
E	PRO180
E	LYS181
E	ALA182
E	GLY183
E	LYS184
E	THR185
E	MSE186
E	PHE355
F	ARG366
F	LYS367

site_id	BC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG E 1001

Chain	Residue
E	THR185
E	GLU211

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BEF E 1002

Chain	Residue
E	PRO180
E	LYS184
E	GLU211
E	ARG212
F	GLY337

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SPD E 420

Chain	Residue
E	GLU234
E	PRO235
E	SER237
E	ARG238
E	GLN241

site_id	BC9
Number of Residues	13
Details	BINDING SITE FOR RESIDUE ADP F 1000

Chain	Residue
A	ARG366
A	LYS367
F	LYS181
F	ALA182
F	GLY183
F	LYS184
F	THR185
F	MSE186
F	ARG212
F	GLU215
F	PHE355
F	MG1001
F	BEF1002

site_id	CC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG F 1001

Chain	Residue
F	THR185
F	ADP1000
F	BEF1002

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SPD G 7

Chain	Residue
A	GLY282
C	GLY282
G	U1
G	U2

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	450
Details	Domain: {"description":"Rho RNA-BD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01203","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	54
Details	Region: {"description":"RNA-binding 1"}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	24
Details	Region: {"description":"RNA-binding 2"}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	30
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	36
Details	Binding site: {}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	6
Details	Site: {"description":"RNA-binding 2"}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ohh

Chain	Residue	Details
A	ARG366

site_id	CSA10
Number of Residues	3
Details	Annotated By Reference To The Literature 1ohh

Chain	Residue	Details
D	ARG212
D	GLU211
D	LYS184

site_id	CSA11
Number of Residues	3
Details	Annotated By Reference To The Literature 1ohh

Chain	Residue	Details
E	ARG212
E	GLU211
E	LYS184

site_id	CSA12
Number of Residues	3
Details	Annotated By Reference To The Literature 1ohh

Chain	Residue	Details
F	ARG212
F	GLU211
F	LYS184

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1ohh

Chain	Residue	Details
B	ARG366

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1ohh

Chain	Residue	Details
C	ARG366

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1ohh

Chain	Residue	Details
D	ARG366

site_id	CSA5
Number of Residues	1
Details	Annotated By Reference To The Literature 1ohh

Chain	Residue	Details
E	ARG366

site_id	CSA6
Number of Residues	1
Details	Annotated By Reference To The Literature 1ohh

Chain	Residue	Details
F	ARG366

site_id	CSA7
Number of Residues	3
Details	Annotated By Reference To The Literature 1ohh

Chain	Residue	Details
A	ARG212
A	GLU211
A	LYS184

site_id	CSA8
Number of Residues	3
Details	Annotated By Reference To The Literature 1ohh

Chain	Residue	Details
B	ARG212
B	GLU211
B	LYS184

site_id	CSA9
Number of Residues	3
Details	Annotated By Reference To The Literature 1ohh

Chain	Residue	Details
C	ARG212
C	GLU211
C	LYS184

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)