3I4Z
Crystal structure of the dimethylallyl tryptophan synthase FgaPT2 from Aspergillus fumigatus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004659 | molecular_function | prenyltransferase activity |
| A | 0009820 | biological_process | alkaloid metabolic process |
| A | 0009821 | biological_process | alkaloid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| A | 0035835 | biological_process | indole alkaloid biosynthetic process |
| A | 0035837 | biological_process | ergot alkaloid biosynthetic process |
| A | 0050364 | molecular_function | tryptophan dimethylallyltransferase activity |
| A | 1900809 | biological_process | fumigaclavine C biosynthetic process |
| B | 0004659 | molecular_function | prenyltransferase activity |
| B | 0009820 | biological_process | alkaloid metabolic process |
| B | 0009821 | biological_process | alkaloid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0035835 | biological_process | indole alkaloid biosynthetic process |
| B | 0035837 | biological_process | ergot alkaloid biosynthetic process |
| B | 0050364 | molecular_function | tryptophan dimethylallyltransferase activity |
| B | 1900809 | biological_process | fumigaclavine C biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BU2 A 460 |
| Chain | Residue |
| A | TYR191 |
| A | ARG244 |
| A | HOH505 |
| A | HOH705 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BU2 B 460 |
| Chain | Residue |
| B | ARG244 |
| B | LEU263 |
| B | TYR310 |
| B | HOH547 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE BU2 A 461 |
| Chain | Residue |
| A | LEU81 |
| A | LEU325 |
| A | ALA397 |
| A | BU2465 |
| A | HOH553 |
| A | HOH556 |
| A | HOH628 |
| A | ILE80 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE BU2 A 462 |
| Chain | Residue |
| A | LEU92 |
| A | MET372 |
| A | THR375 |
| A | TYR376 |
| A | THR379 |
| A | TYR383 |
| A | HOH712 |
| A | HOH796 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE BU2 A 463 |
| Chain | Residue |
| A | ALA312 |
| A | LEU315 |
| A | ILE320 |
| A | ASP322 |
| A | GLU323 |
| A | HOH528 |
| B | TYR314 |
| B | PRO316 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE BU2 B 461 |
| Chain | Residue |
| B | ILE80 |
| B | LEU81 |
| B | LEU325 |
| B | ALA397 |
| B | HOH491 |
| B | HOH501 |
| B | HOH554 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE BU2 A 464 |
| Chain | Residue |
| A | TYR84 |
| A | LEU317 |
| A | GLY318 |
| A | TYR394 |
| A | GLN415 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BU2 A 465 |
| Chain | Residue |
| A | PRO326 |
| A | TYR345 |
| A | THR347 |
| A | TYR398 |
| A | BU2461 |
| A | HOH815 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 466 |
| Chain | Residue |
| A | SER286 |
| A | ARG404 |
| A | ASP405 |
| A | ARG406 |
| A | HOH611 |
| site_id | BC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 467 |
| Chain | Residue |
| A | THR119 |
| A | HIS120 |
| A | TRP123 |
| A | LYS145 |
| A | THR149 |
| A | LEU150 |
| A | ASP405 |
| A | HOH611 |
| A | HOH613 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 468 |
| Chain | Residue |
| A | ARG235 |
| A | ALA271 |
| A | ASP274 |
| A | HOH493 |
| A | HOH494 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 469 |
| Chain | Residue |
| A | LEU138 |
| A | GLU139 |
| A | ARG142 |
| A | HOH489 |
| A | HOH821 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19706516","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
