3I1F
Gamma-subunit of the translation initiation factor 2 from S. solfataricus in complex with Gpp(CH2)p
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0001731 | biological_process | formation of translation preinitiation complex |
| A | 0003743 | molecular_function | translation initiation factor activity |
| A | 0003746 | molecular_function | translation elongation factor activity |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0006412 | biological_process | translation |
| A | 0006413 | biological_process | translational initiation |
| A | 0006414 | biological_process | translational elongation |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000049 | molecular_function | tRNA binding |
| B | 0001731 | biological_process | formation of translation preinitiation complex |
| B | 0003743 | molecular_function | translation initiation factor activity |
| B | 0003746 | molecular_function | translation elongation factor activity |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005525 | molecular_function | GTP binding |
| B | 0006412 | biological_process | translation |
| B | 0006413 | biological_process | translational initiation |
| B | 0006414 | biological_process | translational elongation |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GCP A 416 |
| Chain | Residue |
| A | LEU41 |
| A | HOH534 |
| A | HOH571 |
| A | LYS42 |
| A | ARG43 |
| A | GLY44 |
| A | VAL223 |
| A | LYS225 |
| A | SER278 |
| A | ARG280 |
| A | ALA296 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 A 417 |
| Chain | Residue |
| A | PRO182 |
| A | ILE189 |
| A | ASN190 |
| A | THR371 |
| A | GLU379 |
| A | HOH557 |
| A | HOH564 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 418 |
| Chain | Residue |
| A | VAL6 |
| A | PHE85 |
| A | HOH546 |
| A | HOH562 |
| A | HOH563 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GCP B 416 |
| Chain | Residue |
| B | ASP19 |
| B | HIS20 |
| B | GLY21 |
| B | LYS22 |
| B | THR23 |
| B | THR24 |
| B | ASN121 |
| B | LYS150 |
| B | HOH421 |
| B | HOH554 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 B 417 |
| Chain | Residue |
| B | LYS332 |
| B | ASN334 |
| B | HOH470 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 B 418 |
| Chain | Residue |
| B | GLY258 |
| B | LEU259 |
| B | ARG260 |
| B | ASN310 |
| B | LEU311 |
| B | HOH489 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00119, ECO:0000269|PubMed:25690901, ECO:0007744|PDB:4RD1 |
| Chain | Residue | Details |
| A | ASP19 | |
| A | GLY44 | |
| B | ASP19 | |
| B | GLY44 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00119, ECO:0000269|PubMed:16407071, ECO:0000269|PubMed:25690901, ECO:0007744|PDB:2AHO |
| Chain | Residue | Details |
| A | THR23 | |
| A | THR46 | |
| B | THR23 | |
| B | THR46 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q8U082, ECO:0000255|HAMAP-Rule:MF_00119 |
| Chain | Residue | Details |
| A | CYS59 | |
| A | CYS62 | |
| A | CYS74 | |
| A | CYS77 | |
| B | CYS59 | |
| B | CYS62 | |
| B | CYS74 | |
| B | CYS77 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00119, ECO:0000269|PubMed:25690901, ECO:0007744|PDB:4RCY, ECO:0007744|PDB:4RD1 |
| Chain | Residue | Details |
| A | ASN149 | |
| A | SER184 | |
| B | ASN149 | |
| B | SER184 |
