3I0W
Crystal structure of Clostridium acetobutylicum 8-oxoguanine glycosylase/lyase in complex with dsDNA containing cytosine opposite to 8-oxoG
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003684 | molecular_function | damaged DNA binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0006281 | biological_process | DNA repair |
| A | 0006284 | biological_process | base-excision repair |
| A | 0006289 | biological_process | nucleotide-excision repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008534 | molecular_function | oxidized purine nucleobase lesion DNA N-glycosylase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019104 | molecular_function | DNA N-glycosylase activity |
| A | 0140078 | molecular_function | class I DNA-(apurinic or apyrimidinic site) endonuclease activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 291 |
| Chain | Residue |
| A | LYS50 |
| A | VAL51 |
| A | ASN65 |
| A | LEU148 |
| A | GLU149 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 292 |
| Chain | Residue |
| A | EDO293 |
| A | HOH384 |
| A | PHE48 |
| A | ASP114 |
| A | PRO115 |
| A | LYS202 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 293 |
| Chain | Residue |
| A | VAL74 |
| A | TYR78 |
| A | ARG112 |
| A | EDO292 |
| A | HOH531 |
| A | HOH550 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 294 |
| Chain | Residue |
| A | GLU142 |
| A | ILE154 |
| A | TYR155 |
| A | LYS269 |
| A | HOH304 |
| A | HOH361 |
| A | HOH435 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 295 |
| Chain | Residue |
| A | GLU22 |
| A | LEU23 |
| A | LYS24 |
| A | LYS56 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 296 |
| Chain | Residue |
| A | LYS214 |
| A | PHE216 |
| A | VAL219 |
| A | HOH389 |
| B | DC22 |
| B | HOH53 |
