3I0W

Crystal structure of Clostridium acetobutylicum 8-oxoguanine glycosylase/lyase in complex with dsDNA containing cytosine opposite to 8-oxoG

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0003824	molecular_function	catalytic activity
A	0006281	biological_process	DNA repair
A	0006284	biological_process	base-excision repair
A	0006289	biological_process	nucleotide-excision repair
A	0008534	molecular_function	oxidized purine nucleobase lesion DNA N-glycosylase activity
A	0140097	molecular_function	catalytic activity, acting on DNA

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 291

Chain	Residue
A	LYS50
A	VAL51
A	ASN65
A	LEU148
A	GLU149

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 292

Chain	Residue
A	EDO293
A	HOH384
A	PHE48
A	ASP114
A	PRO115
A	LYS202

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 293

Chain	Residue
A	VAL74
A	TYR78
A	ARG112
A	EDO292
A	HOH531
A	HOH550

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site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 294

Chain	Residue
A	GLU142
A	ILE154
A	TYR155
A	LYS269
A	HOH304
A	HOH361
A	HOH435

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 295

Chain	Residue
A	GLU22
A	LEU23
A	LYS24
A	LYS56

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site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 296

Chain	Residue
A	LYS214
A	PHE216
A	VAL219
A	HOH389
B	DC22
B	HOH53

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