Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016020 | cellular_component | membrane |
| A | 0030154 | biological_process | cell differentiation |
| B | 0007219 | biological_process | Notch signaling pathway |
| B | 0007275 | biological_process | multicellular organism development |
| B | 0016020 | cellular_component | membrane |
| B | 0030154 | biological_process | cell differentiation |
| C | 0016020 | cellular_component | membrane |
| C | 0030154 | biological_process | cell differentiation |
| D | 0007219 | biological_process | Notch signaling pathway |
| D | 0007275 | biological_process | multicellular organism development |
| D | 0016020 | cellular_component | membrane |
| D | 0030154 | biological_process | cell differentiation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 1 |
| Chain | Residue |
| A | ASP1458 |
| A | ASN1461 |
| A | VAL1463 |
| A | SER1465 |
| A | ASP1476 |
| A | ASP1479 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 1666 |
| Chain | Residue |
| A | ASP1507 |
| A | ASP1518 |
| A | ASP1521 |
| A | TYR1500 |
| A | ASP1503 |
| A | HIS1505 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 1667 |
| Chain | Residue |
| A | HIS1540 |
| A | ASP1543 |
| A | HIS1545 |
| A | ASP1547 |
| A | ASP1558 |
| A | ASP1561 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 1668 |
| Chain | Residue |
| A | HIS1471 |
| A | TRP1475 |
| A | ASP1486 |
| A | PRO1487 |
| A | TRP1488 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 1 |
| Chain | Residue |
| C | ASP1458 |
| C | ASN1461 |
| C | VAL1463 |
| C | SER1465 |
| C | ASP1476 |
| C | ASP1479 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 1666 |
| Chain | Residue |
| C | TYR1500 |
| C | ASP1503 |
| C | HIS1505 |
| C | ASP1507 |
| C | ASP1518 |
| C | ASP1521 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 1667 |
| Chain | Residue |
| C | HIS1540 |
| C | ASP1543 |
| C | HIS1545 |
| C | ASP1547 |
| C | ASP1558 |
| C | ASP1561 |
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. VCSLqcNnHACGWDG |
| Chain | Residue | Details |
| A | VAL1463-GLY1477 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 80 |
| Details | Repeat: {"description":"LNR 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00525","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 82 |
| Details | Repeat: {"description":"LNR 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00525","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 78 |
| Details | Repeat: {"description":"LNR 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00525","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Site: {"description":"Cleavage; by ADAM17","evidences":[{"source":"UniProtKB","id":"Q01705","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"O-linked (GalNAc...) threonine","evidences":[{"source":"PubMed","id":"24226769","evidenceCode":"ECO:0000269"}]} |
