3HPV

Crystal Structure Analysis of the 2,3-dioxygenase LapB from Pseudomonas sp. KL28

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0006725	biological_process	obsolete cellular aromatic compound metabolic process
A	0008198	molecular_function	ferrous iron binding
A	0018577	molecular_function	catechol 2,3-dioxygenase activity
A	0019439	biological_process	obsolete aromatic compound catabolic process
A	0046872	molecular_function	metal ion binding
A	0051213	molecular_function	dioxygenase activity
B	0003824	molecular_function	catalytic activity
B	0006725	biological_process	obsolete cellular aromatic compound metabolic process
B	0008198	molecular_function	ferrous iron binding
B	0018577	molecular_function	catechol 2,3-dioxygenase activity
B	0019439	biological_process	obsolete aromatic compound catabolic process
B	0046872	molecular_function	metal ion binding
B	0051213	molecular_function	dioxygenase activity
C	0003824	molecular_function	catalytic activity
C	0006725	biological_process	obsolete cellular aromatic compound metabolic process
C	0008198	molecular_function	ferrous iron binding
C	0018577	molecular_function	catechol 2,3-dioxygenase activity
C	0019439	biological_process	obsolete aromatic compound catabolic process
C	0046872	molecular_function	metal ion binding
C	0051213	molecular_function	dioxygenase activity
D	0003824	molecular_function	catalytic activity
D	0006725	biological_process	obsolete cellular aromatic compound metabolic process
D	0008198	molecular_function	ferrous iron binding
D	0018577	molecular_function	catechol 2,3-dioxygenase activity
D	0019439	biological_process	obsolete aromatic compound catabolic process
D	0046872	molecular_function	metal ion binding
D	0051213	molecular_function	dioxygenase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE2 A 310

Chain	Residue
A	HIS154
A	HIS216
A	GLU267
A	HOH329

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE2 B 310

Chain	Residue
B	HIS154
B	HIS216
B	GLU267
B	HOH330
B	HOH375

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE2 C 310

Chain	Residue
C	HIS154
C	HIS216
C	TYR257
C	GLU267
C	HOH331

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site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE2 D 310

Chain	Residue
D	HIS154
D	HIS216
D	TYR257
D	GLU267
D	HOH332

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Functional Information from PROSITE/UniProt

site_id	PS00082
Number of Residues	22
Details	EXTRADIOL_DIOXYGENAS Extradiol ring-cleavage dioxygenases signature. TrHgvtrgctIYawDPsGnrfE

Chain	Residue	Details
A	THR246-GLU267

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