3HOB

Factor VIII Trp2313-His2315 segment is involved in membrane binding as shown by crystal structure of complex between factor VIII C2 domain and an inhibitor

Functional Information from PROSITE/UniProt

site_id	PS01285
Number of Residues	30
Details	FA58C_1 Coagulation factors 5/8 type C domain (FA58C) signature 1. AWrpqvnnpke......WLqVDfqktmkVtgVtTQG

Chain	Residue	Details
M	ALA2218-GLY2247

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site_id	PS01286
Number of Residues	17
Details	FA58C_2 Coagulation factors 5/8 type C domain (FA58C) signature 2. Pqswvhqia..LRmEVlGC

Chain	Residue	Details
M	PRO2310-CYS2326

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	304
Details	Domain: {"description":"F5/8 type C 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00081","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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