3HKS

Crystal structure of eukaryotic translation initiation factor eIF-5A2 from Arabidopsis thaliana

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003729	molecular_function	mRNA binding
A	0003743	molecular_function	translation initiation factor activity
A	0003746	molecular_function	translation elongation factor activity
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005794	cellular_component	Golgi apparatus
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0006413	biological_process	translational initiation
A	0006414	biological_process	translational elongation
A	0009611	biological_process	response to wounding
A	0009617	biological_process	response to bacterium
A	0010494	cellular_component	cytoplasmic stress granule
A	0012501	biological_process	programmed cell death
A	0034050	biological_process	symbiont-induced defense-related programmed cell death
A	0042742	biological_process	defense response to bacterium
A	0043022	molecular_function	ribosome binding
B	0003723	molecular_function	RNA binding
B	0003729	molecular_function	mRNA binding
B	0003743	molecular_function	translation initiation factor activity
B	0003746	molecular_function	translation elongation factor activity
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005794	cellular_component	Golgi apparatus
B	0005829	cellular_component	cytosol
B	0006412	biological_process	translation
B	0006413	biological_process	translational initiation
B	0006414	biological_process	translational elongation
B	0009611	biological_process	response to wounding
B	0009617	biological_process	response to bacterium
B	0010494	cellular_component	cytoplasmic stress granule
B	0012501	biological_process	programmed cell death
B	0034050	biological_process	symbiont-induced defense-related programmed cell death
B	0042742	biological_process	defense response to bacterium
B	0043022	molecular_function	ribosome binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 160

Chain	Residue
A	GLN21
A	ASN25
A	ILE26
A	ARG27
A	GLY30
A	HOH188
A	HOH247

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 161

Chain	Residue
A	PRO83
A	VAL85
A	HOH232
A	TYR19
A	HIS31

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 162

Chain	Residue
A	THR49
A	ASP112
A	HOH234
B	SER45
B	HIS58
B	HOH206
B	HOH238

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 163

Chain	Residue
A	LYS115
A	GLN148
A	ILE149
A	HOH209

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO B 160

Chain	Residue
B	LYS115
B	PRO117
B	GLN148
B	ILE149
B	HOH208
B	HOH212

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO B 161

Chain	Residue
A	LYS48
B	LEU92
B	LYS134
B	ILE136

---

Functional Information from PROSITE/UniProt

site_id	PS00302
Number of Residues	8
Details	IF5A_HYPUSINE Eukaryotic initiation factor 5A hypusine signature. TGKHGhAK

Chain	Residue	Details
A	THR49-LYS56

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Modified residue: {"description":"Hypusine","evidences":[{"source":"UniProtKB","id":"Q9XI91","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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