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3HJW

Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA

Functional Information from GO Data
ChainGOidnamespacecontents
A0000495biological_processbox H/ACA sno(s)RNA 3'-end processing
A0001522biological_processpseudouridine synthesis
A0003723molecular_functionRNA binding
A0005515molecular_functionprotein binding
A0006396biological_processRNA processing
A0008033biological_processtRNA processing
A0009451biological_processRNA modification
A0009982molecular_functionpseudouridine synthase activity
A0016853molecular_functionisomerase activity
A0031118biological_processrRNA pseudouridine synthesis
A0031119biological_processtRNA pseudouridine synthesis
A0031120biological_processsnRNA pseudouridine synthesis
A0160148molecular_functiontRNA pseudouridine(55) synthase activity
A1990481biological_processmRNA pseudouridine synthesis
B0001522biological_processpseudouridine synthesis
B0030515molecular_functionsnoRNA binding
B0042254biological_processribosome biogenesis
C0001682biological_processtRNA 5'-leader removal
C0003723molecular_functionRNA binding
C0003735molecular_functionstructural constituent of ribosome
C0004526molecular_functionribonuclease P activity
C0005737cellular_componentcytoplasm
C0005840cellular_componentribosome
C0006364biological_processrRNA processing
C0006412biological_processtranslation
C0008033biological_processtRNA processing
C0019843molecular_functionrRNA binding
C0042254biological_processribosome biogenesis
C1990904cellular_componentribonucleoprotein complex
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN B 1
ChainResidue
BCYS8
BCYS11
BCYS20
BCYS23

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE K E 2
ChainResidue
ATYR113
ATHR181
EFHU10
EHOH63
EHOH80

Functional Information from PROSITE/UniProt
site_idPS01082
Number of Residues18
DetailsRIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CeekeIPYiyVpSKkeLG
ChainResidueDetails
CCYS71-GLY88

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_01081
ChainResidueDetails
AASP85

Catalytic Information from CSA
site_idCSA1
Number of Residues2
DetailsAnnotated By Reference To The Literature 1ze1
ChainResidueDetails
AASP85
ATYR113

229183

PDB entries from 2024-12-18

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