3HHK
HCV NS5b polymerase complex with a substituted benzothiadizine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003968 | molecular_function | RNA-dependent RNA polymerase activity |
| A | 0039694 | biological_process | viral RNA genome replication |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003968 | molecular_function | RNA-dependent RNA polymerase activity |
| B | 0039694 | biological_process | viral RNA genome replication |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 77Z A 564 |
| Chain | Residue |
| A | PHE193 |
| A | TYR415 |
| A | TYR448 |
| A | GLY449 |
| A | SER556 |
| A | HOH569 |
| A | HOH626 |
| A | HOH662 |
| A | ARG200 |
| A | THR287 |
| A | ASN291 |
| A | ASN316 |
| A | ASP318 |
| A | CYS366 |
| A | SER368 |
| A | MET414 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE 77Z B 564 |
| Chain | Residue |
| B | PHE193 |
| B | ARG200 |
| B | THR287 |
| B | ASN291 |
| B | ASN316 |
| B | ASP318 |
| B | CYS366 |
| B | SER368 |
| B | LEU384 |
| B | MET414 |
| B | TYR415 |
| B | TYR448 |
| B | GLY449 |
| B | SER556 |
| B | HOH566 |
| B | HOH591 |
| B | HOH721 |
