3HHC
Interferon-lambda is functionally an interferon but structurally related to the IL-10 family
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005125 | molecular_function | cytokine activity |
| A | 0007259 | biological_process | cell surface receptor signaling pathway via JAK-STAT |
| A | 0050778 | biological_process | positive regulation of immune response |
| A | 0051607 | biological_process | defense response to virus |
| B | 0005125 | molecular_function | cytokine activity |
| B | 0007259 | biological_process | cell surface receptor signaling pathway via JAK-STAT |
| B | 0050778 | biological_process | positive regulation of immune response |
| B | 0051607 | biological_process | defense response to virus |
| C | 0005125 | molecular_function | cytokine activity |
| C | 0007259 | biological_process | cell surface receptor signaling pathway via JAK-STAT |
| C | 0050778 | biological_process | positive regulation of immune response |
| C | 0051607 | biological_process | defense response to virus |
| D | 0005125 | molecular_function | cytokine activity |
| D | 0007259 | biological_process | cell surface receptor signaling pathway via JAK-STAT |
| D | 0050778 | biological_process | positive regulation of immune response |
| D | 0051607 | biological_process | defense response to virus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 164 |
| Chain | Residue |
| A | THR92 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 165 |
| Chain | Residue |
| B | ARG101 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD A 169 |
| Chain | Residue |
| A | GLU29 |
| C | ARG41 |
| C | ARG45 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD A 170 |
| Chain | Residue |
| A | TRP47 |
| A | ARG124 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 171 |
| Chain | Residue |
| A | PHE146 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IOD A 172 |
| Chain | Residue |
| A | ARG50 |
| A | ARG151 |
| A | ASP152 |
| A | ASP48 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD A 173 |
| Chain | Residue |
| A | ASN154 |
| A | SER158 |
| A | HOH186 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD B 164 |
| Chain | Residue |
| B | GLN88 |
| B | THR92 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD B 165 |
| Chain | Residue |
| B | LYS24 |
| site_id | BC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD B 167 |
| Chain | Residue |
| B | HIS120 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IOD B 168 |
| Chain | Residue |
| B | ASN154 |
| B | SER158 |
| B | LEU161 |
| B | CYS162 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD B 170 |
| Chain | Residue |
| A | GLN105 |
| B | GLY111 |
| site_id | BC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD C 164 |
| Chain | Residue |
| C | THR92 |
| site_id | BC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD C 165 |
| Chain | Residue |
| C | PHE146 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD C 166 |
| Chain | Residue |
| C | ASP48 |
| C | ARG50 |
| C | ASP152 |
| site_id | BC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD C 167 |
| Chain | Residue |
| C | GLN53 |
| site_id | BC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD C 168 |
| Chain | Residue |
| C | LYS70 |
| site_id | BC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD C 169 |
| Chain | Residue |
| C | ARG2 |
| site_id | CC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD C 170 |
| Chain | Residue |
| B | PRO112 |
| site_id | CC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD C 171 |
| Chain | Residue |
| C | HIS91 |
| C | HIS95 |
| site_id | CC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD C 172 |
| Chain | Residue |
| A | LYS21 |
| site_id | CC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD C 173 |
| Chain | Residue |
| A | ARG45 |
| C | GLU29 |
| site_id | CC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD C 174 |
| Chain | Residue |
| C | HIS120 |
| site_id | CC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD C 176 |
| Chain | Residue |
| C | ILE6 |
| site_id | CC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD D 164 |
| Chain | Residue |
| B | GLU29 |
| D | ARG41 |
| D | ARG45 |
| site_id | CC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD D 165 |
| Chain | Residue |
| D | PHE146 |
| site_id | CC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD D 167 |
| Chain | Residue |
| D | LYS70 |
| site_id | DC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD D 168 |
| Chain | Residue |
| D | GLN88 |
| D | PRO89 |
