3HE3
Crystal Structure of UDP-galactopyranose mutase in complex with UDP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0005829 | cellular_component | cytosol |
| C | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0005829 | cellular_component | cytosol |
| D | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0005829 | cellular_component | cytosol |
| E | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| E | 0016853 | molecular_function | isomerase activity |
| E | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0005829 | cellular_component | cytosol |
| F | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| F | 0016853 | molecular_function | isomerase activity |
| F | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0005829 | cellular_component | cytosol |
| G | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| G | 0016853 | molecular_function | isomerase activity |
| G | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| H | 0000166 | molecular_function | nucleotide binding |
| H | 0005829 | cellular_component | cytosol |
| H | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| H | 0016853 | molecular_function | isomerase activity |
| H | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| I | 0000166 | molecular_function | nucleotide binding |
| I | 0005829 | cellular_component | cytosol |
| I | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| I | 0016853 | molecular_function | isomerase activity |
| I | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| J | 0000166 | molecular_function | nucleotide binding |
| J | 0005829 | cellular_component | cytosol |
| J | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| J | 0016853 | molecular_function | isomerase activity |
| J | 0050660 | molecular_function | flavin adenine dinucleotide binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE UDP A 400 |
| Chain | Residue |
| A | PHE175 |
| A | ARG305 |
| A | TYR335 |
| A | TYR370 |
| A | HOH410 |
| A | HOH421 |
| A | HOH540 |
| A | HOH855 |
| A | HOH940 |
| A | PHE176 |
| A | TYR179 |
| A | THR180 |
| A | TRP184 |
| A | ARG198 |
| A | VAL199 |
| A | TYR209 |
| A | ASN296 |
| site_id | AC2 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE FAD A 450 |
| Chain | Residue |
| A | VAL35 |
| A | GLY36 |
| A | GLY38 |
| A | PHE39 |
| A | ALA40 |
| A | ASP59 |
| A | ARG60 |
| A | ARG61 |
| A | GLY66 |
| A | ASN67 |
| A | TYR82 |
| A | PRO84 |
| A | HIS85 |
| A | ILE86 |
| A | THR241 |
| A | ASP242 |
| A | TYR243 |
| A | LEU277 |
| A | TYR334 |
| A | GLY363 |
| A | ARG364 |
| A | TYR371 |
| A | ASN372 |
| A | MET373 |
| A | VAL376 |
| A | HOH401 |
| A | HOH402 |
| A | HOH403 |
| A | HOH415 |
| A | HOH432 |
| A | HOH798 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE UDP B 400 |
| Chain | Residue |
| B | PHE175 |
| B | PHE176 |
| B | TYR179 |
| B | THR180 |
| B | TRP184 |
| B | VAL195 |
| B | ARG198 |
| B | VAL199 |
| B | TYR209 |
| B | ASN296 |
| B | ARG305 |
| B | TYR335 |
| B | TYR370 |
| B | HOH464 |
| B | HOH472 |
| B | HOH793 |
| site_id | AC4 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE FAD B 450 |
| Chain | Residue |
| B | VAL35 |
| B | GLY36 |
| B | GLY38 |
| B | PHE39 |
| B | ALA40 |
| B | ASP59 |
| B | ARG60 |
| B | ARG61 |
| B | GLY66 |
| B | ASN67 |
| B | TYR82 |
| B | PRO84 |
| B | HIS85 |
| B | ILE86 |
| B | THR241 |
| B | ASP242 |
| B | TYR243 |
| B | LEU277 |
| B | TYR334 |
| B | GLY363 |
| B | ARG364 |
| B | TYR371 |
| B | ASN372 |
| B | MET373 |
| B | VAL376 |
| B | HOH409 |
| B | HOH413 |
| B | HOH415 |
| B | HOH464 |
| B | HOH751 |
| B | HOH818 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE UDP C 400 |
| Chain | Residue |
| C | TRP184 |
| C | VAL195 |
| C | THR196 |
| C | ARG198 |
| C | VAL199 |
| C | TYR209 |
| C | ASN296 |
| C | ARG305 |
| C | TYR335 |
| C | TYR370 |
| C | HOH405 |
| C | HOH437 |
| C | HOH1087 |
| C | PHE175 |
| C | PHE176 |
| C | TYR179 |
| C | THR180 |
| site_id | AC6 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE FAD C 450 |
| Chain | Residue |
| C | VAL35 |
| C | GLY36 |
| C | GLY38 |
| C | PHE39 |
| C | ALA40 |
| C | ASP59 |
| C | ARG60 |
| C | ARG61 |
| C | GLY66 |
| C | ASN67 |
| C | TYR82 |
| C | PRO84 |
| C | HIS85 |
| C | ILE86 |
| C | THR241 |
| C | ASP242 |
| C | TYR243 |
| C | THR258 |
| C | LEU277 |
| C | TYR334 |
| C | GLY363 |
| C | ARG364 |
| C | TYR371 |
| C | ASN372 |
| C | MET373 |
| C | HOH399 |
| C | HOH417 |
| C | HOH428 |
| C | HOH434 |
| C | HOH460 |
| C | HOH920 |
| site_id | AC7 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE UDP D 400 |
| Chain | Residue |
| D | PHE175 |
| D | PHE176 |
| D | TYR179 |
| D | THR180 |
| D | TRP184 |
| D | VAL195 |
| D | ARG198 |
| D | VAL199 |
| D | TYR209 |
| D | ASN296 |
| D | ARG305 |
| D | TYR335 |
| D | TYR370 |
| D | HOH544 |
| D | HOH1028 |
| D | HOH1090 |
| D | HOH1091 |
| site_id | AC8 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE FAD D 450 |
| Chain | Residue |
| D | VAL35 |
| D | GLY36 |
| D | GLY38 |
| D | PHE39 |
| D | ALA40 |
| D | ASP59 |
| D | ARG60 |
| D | ARG61 |
| D | GLY66 |
| D | ASN67 |
| D | TYR82 |
| D | PRO84 |
| D | HIS85 |
| D | ILE86 |
| D | THR241 |
| D | ASP242 |
| D | TYR243 |
| D | THR258 |
| D | LEU277 |
| D | TYR334 |
| D | GLY363 |
| D | ARG364 |
| D | TYR371 |
| D | ASN372 |
| D | MET373 |
| D | VAL376 |
| D | HOH398 |
| D | HOH401 |
| D | HOH402 |
| D | HOH411 |
| site_id | AC9 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE UDP E 400 |
| Chain | Residue |
| E | ILE122 |
| E | PHE175 |
| E | PHE176 |
| E | TYR179 |
| E | THR180 |
| E | TRP184 |
| E | ARG198 |
| E | VAL199 |
| E | TYR209 |
| E | ASN296 |
| E | ARG305 |
| E | TYR335 |
| E | TYR370 |
| E | HOH399 |
| E | HOH593 |
| E | HOH1010 |
| E | HOH1015 |
| site_id | BC1 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE FAD E 450 |
| Chain | Residue |
| E | VAL35 |
| E | GLY36 |
| E | GLY38 |
| E | PHE39 |
| E | ALA40 |
| E | ASP59 |
| E | ARG60 |
| E | ARG61 |
| E | GLY66 |
| E | ASN67 |
| E | TYR82 |
| E | PRO84 |
| E | HIS85 |
| E | ILE86 |
| E | THR241 |
| E | ASP242 |
| E | TYR243 |
| E | LEU277 |
| E | GLY363 |
| E | ARG364 |
| E | TYR371 |
| E | ASN372 |
| E | MET373 |
| E | VAL376 |
| E | HOH404 |
| E | HOH405 |
| E | HOH413 |
| E | HOH421 |
| E | HOH593 |
| E | HOH869 |
| site_id | BC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE UDP F 400 |
| Chain | Residue |
| F | PHE175 |
| F | PHE176 |
| F | TYR179 |
| F | THR180 |
| F | TRP184 |
| F | ARG198 |
| F | VAL199 |
| F | TYR209 |
| F | ASN296 |
| F | ARG305 |
| F | TYR335 |
| F | TYR370 |
| F | HOH413 |
| F | HOH432 |
| F | HOH461 |
| F | HOH534 |
| F | HOH613 |
| site_id | BC3 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE FAD F 450 |
| Chain | Residue |
| F | VAL35 |
| F | GLY36 |
| F | GLY38 |
| F | PHE39 |
| F | ALA40 |
| F | ASP59 |
| F | ARG60 |
| F | ARG61 |
| F | GLY66 |
| F | ASN67 |
| F | TYR82 |
| F | PRO84 |
| F | HIS85 |
| F | ILE86 |
| F | THR241 |
| F | ASP242 |
| F | TYR243 |
| F | THR258 |
| F | LEU277 |
| F | GLY363 |
| F | ARG364 |
| F | TYR371 |
| F | ASN372 |
| F | MET373 |
| F | VAL376 |
| F | HOH398 |
| F | HOH399 |
| F | HOH405 |
| F | HOH411 |
| F | HOH428 |
| F | HOH947 |
| site_id | BC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE UDP G 400 |
| Chain | Residue |
| G | PHE175 |
| G | PHE176 |
| G | TYR179 |
| G | THR180 |
| G | TRP184 |
| G | VAL195 |
| G | ARG198 |
| G | TYR209 |
| G | ASN296 |
| G | ARG305 |
| G | TYR335 |
| G | TYR370 |
| G | HOH441 |
| G | HOH475 |
| G | HOH870 |
| site_id | BC5 |
| Number of Residues | 32 |
| Details | BINDING SITE FOR RESIDUE FAD G 450 |
| Chain | Residue |
| G | GLY36 |
| G | GLY38 |
| G | PHE39 |
| G | ALA40 |
| G | ASP59 |
| G | ARG60 |
| G | ARG61 |
| G | GLY66 |
| G | ASN67 |
| G | TYR82 |
| G | PRO84 |
| G | HIS85 |
| G | ILE86 |
| G | THR241 |
| G | ASP242 |
| G | TYR243 |
| G | ARG244 |
| G | GLY259 |
| G | LEU277 |
| G | TYR334 |
| G | TYR335 |
| G | GLY363 |
| G | ARG364 |
| G | LEU365 |
| G | TYR371 |
| G | ASN372 |
| G | MET373 |
| G | VAL376 |
| G | HOH401 |
| G | HOH407 |
| G | HOH412 |
| G | HOH414 |
| site_id | BC6 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE UDP H 400 |
| Chain | Residue |
| H | PHE175 |
| H | PHE176 |
| H | TYR179 |
| H | THR180 |
| H | TRP184 |
| H | VAL195 |
| H | ARG198 |
| H | VAL199 |
| H | TYR209 |
| H | ASN296 |
| H | ARG305 |
| H | TYR335 |
| H | TYR370 |
| H | HOH564 |
| H | HOH730 |
| H | HOH941 |
| H | HOH1093 |
| H | HOH1094 |
| site_id | BC7 |
| Number of Residues | 33 |
| Details | BINDING SITE FOR RESIDUE FAD H 450 |
| Chain | Residue |
| H | VAL35 |
| H | GLY36 |
| H | GLY38 |
| H | PHE39 |
| H | ALA40 |
| H | ASP59 |
| H | ARG60 |
| H | ARG61 |
| H | GLY66 |
| H | ASN67 |
| H | TYR82 |
| H | PRO84 |
| H | HIS85 |
| H | ILE86 |
| H | THR241 |
| H | ASP242 |
| H | TYR243 |
| H | GLY259 |
| H | LEU277 |
| H | GLU325 |
| H | TYR334 |
| H | GLY363 |
| H | ARG364 |
| H | TYR371 |
| H | ASN372 |
| H | MET373 |
| H | VAL376 |
| H | HOH403 |
| H | HOH411 |
| H | HOH414 |
| H | HOH416 |
| H | HOH423 |
| H | HOH439 |
| site_id | BC8 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE UDP I 400 |
| Chain | Residue |
| I | PHE175 |
| I | PHE176 |
| I | TYR179 |
| I | THR180 |
| I | TRP184 |
| I | VAL195 |
| I | ARG198 |
| I | VAL199 |
| I | TYR209 |
| I | ASN296 |
| I | ARG305 |
| I | TYR335 |
| I | TYR370 |
| I | HOH407 |
| I | HOH692 |
| I | HOH942 |
| I | HOH1095 |
| site_id | BC9 |
| Number of Residues | 32 |
| Details | BINDING SITE FOR RESIDUE FAD I 450 |
| Chain | Residue |
| I | VAL35 |
| I | GLY36 |
| I | GLY38 |
| I | PHE39 |
| I | ALA40 |
| I | ASP59 |
| I | ARG60 |
| I | ARG61 |
| I | GLY66 |
| I | ASN67 |
| I | TYR82 |
| I | PRO84 |
| I | HIS85 |
| I | ILE86 |
| I | ASP242 |
| I | TYR243 |
| I | ARG244 |
| I | THR258 |
| I | GLY259 |
| I | LEU277 |
| I | GLY363 |
| I | ARG364 |
| I | TYR371 |
| I | ASN372 |
| I | MET373 |
| I | VAL376 |
| I | HOH399 |
| I | HOH401 |
| I | HOH402 |
| I | HOH518 |
| I | HOH759 |
| I | HOH1095 |
| site_id | CC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE UDP J 400 |
| Chain | Residue |
| J | PHE175 |
| J | PHE176 |
| J | TYR179 |
| J | THR180 |
| J | TRP184 |
| J | VAL195 |
| J | ARG198 |
| J | TYR209 |
| J | ASN296 |
| J | ARG305 |
| J | TYR335 |
| J | TYR370 |
| J | HOH403 |
| J | HOH440 |
| J | HOH904 |
| J | HOH1096 |
| site_id | CC2 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE FAD J 450 |
| Chain | Residue |
| J | VAL35 |
| J | GLY36 |
| J | GLY38 |
| J | PHE39 |
| J | ALA40 |
| J | ASP59 |
| J | ARG60 |
| J | ARG61 |
| J | GLY66 |
| J | ASN67 |
| J | TYR82 |
| J | PRO84 |
| J | HIS85 |
| J | ILE86 |
| J | HIS88 |
| J | THR241 |
| J | ASP242 |
| J | TYR243 |
| J | THR258 |
| J | LEU277 |
| J | GLY363 |
| J | ARG364 |
| J | TYR371 |
| J | ASN372 |
| J | MET373 |
| J | VAL376 |
| J | HOH405 |
| J | HOH422 |
| J | HOH431 |
| J | HOH439 |
