3HB1
Crystal structure of ed-eya2 complexed with Alf3
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0007275 | biological_process | multicellular organism development |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0007275 | biological_process | multicellular organism development |
| C | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| C | 0007275 | biological_process | multicellular organism development |
| D | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| D | 0007275 | biological_process | multicellular organism development |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE AF3 A 801 |
| Chain | Residue |
| A | HOH143 |
| A | ASP274 |
| A | LEU275 |
| A | ASP276 |
| A | THR447 |
| A | THR448 |
| A | LYS480 |
| A | MG701 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 701 |
| Chain | Residue |
| A | ASP274 |
| A | ASP276 |
| A | ASP502 |
| A | GLU506 |
| A | AF3801 |
| A | HOH143 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE AF3 B 802 |
| Chain | Residue |
| B | ASP274 |
| B | LEU275 |
| B | ASP276 |
| B | THR447 |
| B | THR448 |
| B | LYS480 |
| B | MG702 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 702 |
| Chain | Residue |
| B | HOH137 |
| B | ASP274 |
| B | ASP276 |
| B | ASP502 |
| B | AF3802 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE AF3 C 803 |
| Chain | Residue |
| C | HOH142 |
| C | ASP274 |
| C | ASP276 |
| C | THR447 |
| C | THR448 |
| C | LYS480 |
| C | GLU506 |
| C | MG703 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 703 |
| Chain | Residue |
| C | HOH142 |
| C | ASP274 |
| C | ASP276 |
| C | ASP502 |
| C | GLU506 |
| C | AF3803 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE AF3 D 804 |
| Chain | Residue |
| D | HOH139 |
| D | ASP274 |
| D | LEU275 |
| D | ASP276 |
| D | THR447 |
| D | THR448 |
| D | LYS480 |
| D | MG704 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG D 704 |
| Chain | Residue |
| D | HOH139 |
| D | ASP274 |
| D | ASP276 |
| D | ASP502 |
| D | GLU506 |
| D | AF3804 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"19858093","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"19858093","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19351884","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
