3H87
Rv0301 Rv0300 Toxin Antitoxin Complex from Mycobacterium tuberculosis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004521 | molecular_function | RNA endonuclease activity |
| A | 0004540 | molecular_function | RNA nuclease activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0017148 | biological_process | negative regulation of translation |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004518 | molecular_function | nuclease activity |
| B | 0004521 | molecular_function | RNA endonuclease activity |
| B | 0004540 | molecular_function | RNA nuclease activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0017148 | biological_process | negative regulation of translation |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0097351 | molecular_function | toxin sequestering activity |
| C | 1990748 | biological_process | cellular detoxification |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0097351 | molecular_function | toxin sequestering activity |
| D | 1990748 | biological_process | cellular detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 157 |
| Chain | Residue |
| A | PRO73 |
| A | ARG74 |
| A | ASP77 |
| A | HOH189 |
| A | HOH222 |
| A | HOH239 |
| C | GLN41 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 158 |
| Chain | Residue |
| A | ARG28 |
| A | GLU132 |
| A | HOH210 |
| A | HOH395 |
| A | ASP21 |
| A | TRP25 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 159 |
| Chain | Residue |
| A | ASP99 |
| A | ASP117 |
| A | ASP119 |
| A | HOH181 |
| A | HOH183 |
| C | HOH85 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 157 |
| Chain | Residue |
| B | ARG5 |
| B | SER109 |
| B | HOH270 |
| B | HOH342 |
| B | HOH409 |
| C | ILE20 |
| C | TYR31 |
| C | GOL74 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 158 |
| Chain | Residue |
| B | ASP21 |
| B | ARG28 |
| B | GLU132 |
| B | HOH376 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BME B 159 |
| Chain | Residue |
| B | ASP117 |
| B | LYS118 |
| B | ARG133 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IMD B 160 |
| Chain | Residue |
| B | GLU30 |
| B | ARG31 |
| B | HOH265 |
| B | HOH316 |
| C | ARG44 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL C 74 |
| Chain | Residue |
| B | GLU69 |
| B | GOL157 |
| B | HOH270 |
| C | LEU24 |
| C | ARG35 |
| C | GLN38 |
| C | HOH258 |
| C | HOH315 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 244 |
| Details | Domain: {"description":"PINc","evidences":[{"source":"HAMAP-Rule","id":"MF_00265","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00265","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23011806","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
