Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GLU A 264 |
| Chain | Residue |
| A | TYR61 |
| A | TYR220 |
| A | HOH388 |
| A | HOH438 |
| A | HOH479 |
| A | PRO89 |
| A | LEU90 |
| A | THR91 |
| A | ARG96 |
| A | GLY141 |
| A | SER142 |
| A | THR143 |
| A | GLU193 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE NS3 A 265 |
| Chain | Residue |
| A | ILE92 |
| A | PRO105 |
| A | MET107 |
| A | SER108 |
| A | SER217 |
| A | GLY219 |
| A | SER242 |
| A | ASP248 |
| A | HOH410 |
| A | HOH516 |
| A | HOH548 |
| A | HOH548 |
| A | HOH637 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 266 |
| Chain | Residue |
| A | ARG31 |
| A | HIS46 |
| A | LYS240 |
| A | GLN244 |
| A | GOL273 |
| A | HOH525 |
| A | HOH579 |
| A | HOH581 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 267 |
| Chain | Residue |
| A | ASP139 |
| A | SER140 |
| A | LYS144 |
| A | ARG148 |
| A | HOH411 |
| A | HOH457 |
| A | HOH593 |
| A | HOH604 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 268 |
| Chain | Residue |
| A | GLU27 |
| A | GLY28 |
| A | ASN29 |
| A | GLU30 |
| A | ARG149 |
| A | FLC274 |
| A | HOH349 |
| A | HOH612 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 269 |
| Chain | Residue |
| A | ASN22 |
| A | LEU26 |
| A | ARG64 |
| A | LYS69 |
| A | HOH526 |
| A | HOH626 |
| A | HOH647 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 270 |
| Chain | Residue |
| A | LYS82 |
| A | LYS116 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 271 |
| Chain | Residue |
| A | SER194 |
| A | GLU198 |
| A | ASN214 |
| A | HOH277 |
| A | HOH508 |
| A | HOH601 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 272 |
| Chain | Residue |
| A | GLU33 |
| A | TRP254 |
| A | LYS258 |
| A | HOH412 |
| site_id | BC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 273 |
| Chain | Residue |
| A | GLU42 |
| A | LYS45 |
| A | HIS46 |
| A | LEU241 |
| A | GLN244 |
| A | SO4266 |
| A | HOH525 |
| A | HOH546 |
| A | HOH631 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FLC A 274 |
| Chain | Residue |
| A | ARG148 |
| A | ARG149 |
| A | TRP159 |
| A | ARG163 |
| A | SO4268 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | PRO89 | |
| A | THR91 | |
| A | ARG96 | |
| A | SER142 | |
| A | THR143 | |
| A | GLU193 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | SITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ARG64 | |
| A | ARG148 | |
| A | LYS240 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ILE121 | |
| Chain | Residue | Details |
| A | SER150 | |
| Chain | Residue | Details |
| A | SER184 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
