3H6C

Crystal structure of human alpha-defensin 1 (Mutant Gln22Ala)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0006952	biological_process	defense response
B	0005576	cellular_component	extracellular region
B	0006952	biological_process	defense response

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PEG A 31

Chain	Residue
A	CYS4
A	TYR21

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 32

Chain	Residue
A	ARG14
A	ARG14

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PEG B 31

Chain	Residue
A	TYR16
A	PHE28

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 32

Chain	Residue
B	HOH36
B	HOH39

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL B 33

Chain	Residue
B	PRO7
B	HOH40
A	ARG24

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Functional Information from PROSITE/UniProt

site_id	PS00269
Number of Residues	29
Details	DEFENSIN Mammalian defensins signature. CyCripa.CiagerryGtCiyagrlwafCC

Chain	Residue	Details
A	CYS2-CYS30

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	58
Details	Peptide: {"description":"Neutrophil defensin 1","featureId":"PRO_0000006773"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	56
Details	Peptide: {"description":"Neutrophil defensin 2","featureId":"PRO_0000006774"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"ADP-ribosylarginine; by ART1","evidences":[{"source":"PubMed","id":"21904558","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"21904558","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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