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3H6C

Crystal structure of human alpha-defensin 1 (Mutant Gln22Ala)

Functional Information from GO Data
ChainGOidnamespacecontents
A0005576cellular_componentextracellular region
A0006952biological_processdefense response
B0005576cellular_componentextracellular region
B0006952biological_processdefense response
Functional Information from PDB Data
site_idAC1
Number of Residues2
DetailsBINDING SITE FOR RESIDUE PEG A 31
ChainResidue
ACYS4
ATYR21

site_idAC2
Number of Residues2
DetailsBINDING SITE FOR RESIDUE CL A 32
ChainResidue
AARG14
AARG14

site_idAC3
Number of Residues2
DetailsBINDING SITE FOR RESIDUE PEG B 31
ChainResidue
ATYR16
APHE28

site_idAC4
Number of Residues2
DetailsBINDING SITE FOR RESIDUE CL B 32
ChainResidue
BHOH36
BHOH39

site_idAC5
Number of Residues3
DetailsBINDING SITE FOR RESIDUE CL B 33
ChainResidue
BPRO7
BHOH40
AARG24

Functional Information from PROSITE/UniProt
site_idPS00269
Number of Residues29
DetailsDEFENSIN Mammalian defensins signature. CyCripa.CiagerryGtCiyagrlwafCC
ChainResidueDetails
ACYS2-CYS30

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsMOD_RES: ADP-ribosylarginine; by ART1 => ECO:0000269|PubMed:21904558
ChainResidueDetails
AARG14
AARG24
BARG14
BARG24

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphotyrosine => ECO:0000269|PubMed:21904558
ChainResidueDetails
ATYR21
BTYR21

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PDB entries from 2024-11-06

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