3H3O
Glycerol Kinase H232R with Ethylene Glycol
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004370 | molecular_function | glycerol kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006071 | biological_process | glycerol metabolic process |
| B | 0006072 | biological_process | glycerol-3-phosphate metabolic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016773 | molecular_function | phosphotransferase activity, alcohol group as acceptor |
| B | 0019563 | biological_process | glycerol catabolic process |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004370 | molecular_function | glycerol kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005829 | cellular_component | cytosol |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0006071 | biological_process | glycerol metabolic process |
| C | 0006072 | biological_process | glycerol-3-phosphate metabolic process |
| C | 0016301 | molecular_function | kinase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016773 | molecular_function | phosphotransferase activity, alcohol group as acceptor |
| C | 0019563 | biological_process | glycerol catabolic process |
| O | 0000166 | molecular_function | nucleotide binding |
| O | 0004370 | molecular_function | glycerol kinase activity |
| O | 0005524 | molecular_function | ATP binding |
| O | 0005829 | cellular_component | cytosol |
| O | 0005975 | biological_process | carbohydrate metabolic process |
| O | 0006071 | biological_process | glycerol metabolic process |
| O | 0006072 | biological_process | glycerol-3-phosphate metabolic process |
| O | 0016301 | molecular_function | kinase activity |
| O | 0016740 | molecular_function | transferase activity |
| O | 0016773 | molecular_function | phosphotransferase activity, alcohol group as acceptor |
| O | 0019563 | biological_process | glycerol catabolic process |
| X | 0000166 | molecular_function | nucleotide binding |
| X | 0004370 | molecular_function | glycerol kinase activity |
| X | 0005524 | molecular_function | ATP binding |
| X | 0005829 | cellular_component | cytosol |
| X | 0005975 | biological_process | carbohydrate metabolic process |
| X | 0006071 | biological_process | glycerol metabolic process |
| X | 0006072 | biological_process | glycerol-3-phosphate metabolic process |
| X | 0016301 | molecular_function | kinase activity |
| X | 0016740 | molecular_function | transferase activity |
| X | 0016773 | molecular_function | phosphotransferase activity, alcohol group as acceptor |
| X | 0019563 | biological_process | glycerol catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO O 1000 |
| Chain | Residue |
| O | ARG84 |
| O | GLU85 |
| O | TRP104 |
| O | TYR136 |
| O | ASP246 |
| O | PHE271 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 O 507 |
| Chain | Residue |
| O | THR268 |
| O | HOH530 |
| O | THR14 |
| O | ARG18 |
| O | GLY267 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 O 508 |
| Chain | Residue |
| O | TRP104 |
| O | GLN105 |
| O | ARG107 |
| O | TYR136 |
| O | PHE308 |
| O | THR350 |
| O | HOH513 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 O 509 |
| Chain | Residue |
| O | ARG107 |
| O | SER110 |
| O | THR350 |
| O | SER359 |
| O | ARG362 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO X 1001 |
| Chain | Residue |
| X | ARG84 |
| X | GLU85 |
| X | TRP104 |
| X | TYR136 |
| X | ASP246 |
| X | PHE271 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO X 3125 |
| Chain | Residue |
| X | TRP104 |
| X | GLN105 |
| X | SER106 |
| X | ARG107 |
| X | PHE308 |
| X | THR350 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO X 3126 |
| Chain | Residue |
| X | TYR39 |
| X | ASN49 |
| X | ASN100 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO X 3132 |
| Chain | Residue |
| X | TYR193 |
| X | LEU198 |
| X | GLU199 |
| X | TRP200 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO X 3133 |
| Chain | Residue |
| X | PHE308 |
| X | VAL309 |
| X | PRO347 |
| X | ALA348 |
| X | PHE349 |
| X | THR350 |
| X | GLY351 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 X 507 |
| Chain | Residue |
| X | THR14 |
| X | GLY267 |
| X | THR268 |
| X | HOH513 |
| site_id | BC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PO4 X 508 |
| Chain | Residue |
| X | ARG107 |
| X | ASP134 |
| X | PHE308 |
| X | THR350 |
| X | GLY351 |
| X | LEU352 |
| X | GLY353 |
| X | TRP357 |
| X | ASP358 |
| X | SER359 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1002 |
| Chain | Residue |
| B | ARG84 |
| B | GLU85 |
| B | TRP104 |
| B | TYR136 |
| B | ASP246 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 3130 |
| Chain | Residue |
| B | ASN296 |
| B | LYS298 |
| X | LEU450 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 3131 |
| Chain | Residue |
| B | SER59 |
| B | GLY63 |
| C | SER59 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 B 507 |
| Chain | Residue |
| B | THR14 |
| B | GLY267 |
| B | THR268 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 1003 |
| Chain | Residue |
| C | ARG84 |
| C | GLU85 |
| C | TRP104 |
| C | TYR136 |
| C | ASP246 |
| C | PHE271 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 C 507 |
| Chain | Residue |
| C | GLY13 |
| C | THR14 |
| C | THR268 |
Functional Information from PROSITE/UniProt
| site_id | PS00445 |
| Number of Residues | 21 |
| Details | FGGY_KINASES_2 FGGY family of carbohydrate kinases signature 2. GaVFGLtrgttke.DFVRATLQ |
| Chain | Residue | Details |
| O | GLY363-GLN383 |
| site_id | PS00933 |
| Number of Residues | 13 |
| Details | FGGY_KINASES_1 FGGY family of carbohydrate kinases signature 1. YfSatKVRWLLDN |
| Chain | Residue | Details |
| O | TYR136-ASN148 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 52 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00186","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00186","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19102629","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3D7E","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphohistidine; by HPr","evidences":[{"source":"HAMAP-Rule","id":"MF_00186","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"9162046","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
