Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004476 | molecular_function | mannose-6-phosphate isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0009298 | biological_process | GDP-mannose biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 392 |
| Chain | Residue |
| A | ARG353 |
| A | LYS354 |
| A | ASP355 |
| A | PRO375 |
| A | ASN377 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 393 |
| Chain | Residue |
| A | ASP227 |
| A | SER228 |
| A | THR278 |
| A | HOH575 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 394 |
| Chain | Residue |
| A | ILE96 |
| A | PHE184 |
| A | LEU188 |
| A | SER228 |
| A | GLY229 |
| A | PHE231 |
| A | SER232 |
| A | ALA275 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 395 |
| Chain | Residue |
| A | ASN6 |
| A | LYS307 |
| A | GLY309 |
| A | EDO396 |
| A | HOH443 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 396 |
| Chain | Residue |
| A | ASN6 |
| A | GLY364 |
| A | EDO395 |
| A | HOH404 |
| A | HOH443 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 397 |
| Chain | Residue |
| A | HIS99 |
| A | GLU134 |
| A | LEU249 |
| A | HIS255 |
| A | Y1398 |
| A | HOH625 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE Y1 A 398 |
| Chain | Residue |
| A | GLU134 |
| A | GLU264 |
| A | ZN397 |
| A | HOH582 |
| A | HOH597 |
| A | HOH598 |
| A | HOH625 |
Functional Information from PROSITE/UniProt
| site_id | PS00965 |
| Number of Residues | 9 |
| Details | PMI_I_1 Phosphomannose isomerase type I signature 1. YkDpNHKPE |
| Chain | Residue | Details |
| A | TYR126-GLU134 | |
| site_id | PS00966 |
| Number of Residues | 26 |
| Details | PMI_I_2 Phosphomannose isomerase type I signature 2. HAYLqGvaLEvMAnSDNvLRAGlTPK |
| Chain | Residue | Details |
| A | HIS255-LYS280 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250 |
| Chain | Residue | Details |
| A | ARG274 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | GLN97 | |
| A | HIS99 | |
| A | GLU134 | |
| A | HIS255 | |
