Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007586 | biological_process | digestion |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0097180 | cellular_component | serine protease inhibitor complex |
| A | 0097655 | molecular_function | serpin family protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 247 |
| Chain | Residue |
| A | HOH10 |
| A | GLU70 |
| A | ASN72 |
| A | VAL75 |
| A | GLU80 |
| A | HOH365 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE BRN A 1 |
| Chain | Residue |
| A | SER190 |
| A | CYS191 |
| A | GLN192 |
| A | SER195 |
| A | SER214 |
| A | TRP215 |
| A | GLY216 |
| A | GLY219 |
| A | CYS220 |
| A | GLY226 |
| A | SO4250 |
| A | HOH256 |
| A | HOH454 |
| A | HOH541 |
| A | HOH9 |
| A | HIS57 |
| A | ASP189 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EDO A 246 |
| Chain | Residue |
| A | EDO2 |
| A | HOH10 |
| A | ARG66 |
| A | ILE73 |
| A | ASN74 |
| A | VAL76 |
| A | VAL90 |
| A | HIS91 |
| A | PRO92 |
| A | HOH393 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 2 |
| Chain | Residue |
| A | TYR39 |
| A | HIS40 |
| A | ILE73 |
| A | ASN74 |
| A | VAL90 |
| A | EDO246 |
| A | HOH375 |
| A | HOH446 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO A 3 |
| Chain | Residue |
| A | EDO5 |
| A | HOH14 |
| A | VAL76 |
| A | GLU80 |
| A | PHE82 |
| A | HOH378 |
| A | HOH406 |
| A | HOH463 |
| A | HOH479 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 4 |
| Chain | Residue |
| A | LYS145 |
| A | SER146 |
| A | SER147 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 5 |
| Chain | Residue |
| A | EDO3 |
| A | VAL76 |
| A | ASN95 |
| A | SER96 |
| A | ASN97 |
| A | HOH364 |
| A | HOH406 |
| A | HOH443 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 6 |
| Chain | Residue |
| A | TYR20 |
| A | CYS22 |
| A | THR26 |
| A | ASN97 |
| A | HOH427 |
| A | HOH487 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 248 |
| Chain | Residue |
| A | LYS169 |
| A | PRO173 |
| A | GLY174 |
| A | HOH377 |
| A | HOH422 |
| A | HOH510 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 249 |
| Chain | Residue |
| A | LYS87 |
| A | LYS107 |
| A | THR149 |
| A | TYR151 |
| A | HOH340 |
| A | HOH458 |
| A | HOH490 |
| site_id | BC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 250 |
| Chain | Residue |
| A | BRN1 |
| A | PHE41 |
| A | CYS42 |
| A | HIS57 |
| A | GLN192 |
| A | GLY193 |
| A | SER195 |
| A | HOH477 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASP102 | |
| A | SER195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU70 | |
| A | ASN72 | |
| A | VAL75 | |
| A | GLU80 | |
| A | ASP189 | |
| A | GLN192 | |
| A | SER195 | |
