Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3GW6

Intramolecular Chaperone

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016996	molecular_function	endo-alpha-(2,8)-sialidase activity
B	0016996	molecular_function	endo-alpha-(2,8)-sialidase activity
C	0016996	molecular_function	endo-alpha-(2,8)-sialidase activity
D	0016996	molecular_function	endo-alpha-(2,8)-sialidase activity
E	0016996	molecular_function	endo-alpha-(2,8)-sialidase activity
F	0016996	molecular_function	endo-alpha-(2,8)-sialidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PEG A 2

Chain	Residue
A	ALA943
A	ARG952
A	HIS954

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PEG A 17

Chain	Residue
A	VAL921
A	ARG1048
B	VAL933
B	TYR935

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TAM A 32

Chain	Residue
B	BR39
B	ASP942
A	ASN887
A	GLU914

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE TAM A 35

Chain	Residue
A	HOH113
A	HOH241
A	ASP942
F	ASN887
F	VAL888
F	GLU914

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 40

Chain	Residue
A	HOH222
A	THR846
A	SER847

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR B 11

Chain	Residue
B	HOH126
B	THR846
B	SER847

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PEG B 13

Chain	Residue
B	ASN887

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR B 38

Chain	Residue
A	VAL983
B	PHE955
F	HOH62

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR B 39

Chain	Residue
A	TAM32
B	HOH136
B	HIS954

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PEG E 6

Chain	Residue
C	SER878
E	HOH306
E	VAL888

site_id	BC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PEG E 16

Chain	Residue
E	ASP831

site_id	BC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PEG E 18

Chain	Residue
D	HOH233
D	PRO829
D	THR830
D	ASP831
D	ASN832
E	GLU818
E	GLY819
E	GLU820

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PEG E 21

Chain	Residue
E	TRP940
E	ALA943
E	LYS947
E	ARG952
E	HIS954

site_id	BC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PEG E 22

Chain	Residue
C	GLU818
C	GLY819
C	GLU820
E	PRO829
E	THR830
E	ASP831
E	ASN832

site_id	BC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PEG E 33

Chain	Residue
E	THR849

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR E 36

Chain	Residue
C	HOH149
E	HOH88
E	PHE955

site_id	BC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL E 42

Chain	Residue
E	THR846
E	SER847

site_id	BC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PEG C 3

Chain	Residue
C	ILE828
C	PRO829
C	PRO833

site_id	CC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR C 8

Chain	Residue
C	PHE955
D	VAL983

site_id	CC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL C 9

Chain	Residue
C	THR846
C	SER847

site_id	CC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PEG C 14

Chain	Residue
C	PHE997
C	SER998

site_id	CC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE TAM C 28

Chain	Residue
C	ASP886
C	ASN887
C	GLU914
E	HOH240
E	ASP942

site_id	CC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PEG C 29

Chain	Residue
C	PRO829
C	THR830
C	ASP831
C	ASN832
D	GLU818
D	GLY819
D	GLU820
E	HOH127

site_id	CC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL D 10

Chain	Residue
D	PHE955
E	VAL983

site_id	CC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PEG D 15

Chain	Residue
C	VAL888
D	ASP880
E	THR899

site_id	CC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL D 41

Chain	Residue
C	HOH218
C	ALA959
D	LYS916

site_id	CC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CA F 1

Chain	Residue
B	VAL983
F	PHE955

site_id	DC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PEG F 5

Chain	Residue
F	PHE997
F	TYR1020
F	HOH78
F	ARG837
F	ILE839
F	THR846
F	GLN853
F	THR855
F	THR995

site_id	DC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PEG F 24

Chain	Residue
F	HOH317
F	ASN860
F	ASN861
F	THR862
F	SER864

site_id	DC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PEG F 30

Chain	Residue
A	ASN885
F	SER878

site_id	DC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PEG F 34

Chain	Residue
B	GLU818
B	GLY819
B	GLU820
F	HOH135
F	PRO829
F	THR830
F	ASP831
F	ASN832

site_id	DC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR F 37

Chain	Residue
A	PHE955
F	GLY1038

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	SITE: Cleavage; by autolysis => ECO:0000250\|UniProtKB:O09496

Chain	Residue	Details
A	ALA911
B	ALA911
E	ALA911
C	ALA911
D	ALA911
F	ALA911

Catalytic Information from CSA

site_id	MCSA1
Number of Residues
Details	M-CSA 829

Chain

Residue

Details

site_id	MCSA2
Number of Residues
Details	M-CSA 829

Chain

Residue

Details

site_id	MCSA3
Number of Residues
Details	M-CSA 829

Chain

Residue

Details

site_id	MCSA4
Number of Residues
Details	M-CSA 829

Chain

Residue

Details

site_id	MCSA5
Number of Residues
Details	M-CSA 829

Chain

Residue

Details

site_id	MCSA6
Number of Residues
Details	M-CSA 829

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)