3GVD
Crystal Structure of Serine Acetyltransferase CysE from Yersinia pestis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006535 | biological_process | cysteine biosynthetic process from serine |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009001 | molecular_function | serine O-acetyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0019344 | biological_process | cysteine biosynthetic process |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006535 | biological_process | cysteine biosynthetic process from serine |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009001 | molecular_function | serine O-acetyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| B | 0019344 | biological_process | cysteine biosynthetic process |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006535 | biological_process | cysteine biosynthetic process from serine |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0009001 | molecular_function | serine O-acetyltransferase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016746 | molecular_function | acyltransferase activity |
| C | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| C | 0019344 | biological_process | cysteine biosynthetic process |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006535 | biological_process | cysteine biosynthetic process from serine |
| D | 0008652 | biological_process | amino acid biosynthetic process |
| D | 0009001 | molecular_function | serine O-acetyltransferase activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016746 | molecular_function | acyltransferase activity |
| D | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| D | 0019344 | biological_process | cysteine biosynthetic process |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005829 | cellular_component | cytosol |
| E | 0006535 | biological_process | cysteine biosynthetic process from serine |
| E | 0008652 | biological_process | amino acid biosynthetic process |
| E | 0009001 | molecular_function | serine O-acetyltransferase activity |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016746 | molecular_function | acyltransferase activity |
| E | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| E | 0019344 | biological_process | cysteine biosynthetic process |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005829 | cellular_component | cytosol |
| F | 0006535 | biological_process | cysteine biosynthetic process from serine |
| F | 0008652 | biological_process | amino acid biosynthetic process |
| F | 0009001 | molecular_function | serine O-acetyltransferase activity |
| F | 0016740 | molecular_function | transferase activity |
| F | 0016746 | molecular_function | acyltransferase activity |
| F | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| F | 0019344 | biological_process | cysteine biosynthetic process |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0005829 | cellular_component | cytosol |
| G | 0006535 | biological_process | cysteine biosynthetic process from serine |
| G | 0008652 | biological_process | amino acid biosynthetic process |
| G | 0009001 | molecular_function | serine O-acetyltransferase activity |
| G | 0016740 | molecular_function | transferase activity |
| G | 0016746 | molecular_function | acyltransferase activity |
| G | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| G | 0019344 | biological_process | cysteine biosynthetic process |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0005829 | cellular_component | cytosol |
| H | 0006535 | biological_process | cysteine biosynthetic process from serine |
| H | 0008652 | biological_process | amino acid biosynthetic process |
| H | 0009001 | molecular_function | serine O-acetyltransferase activity |
| H | 0016740 | molecular_function | transferase activity |
| H | 0016746 | molecular_function | acyltransferase activity |
| H | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| H | 0019344 | biological_process | cysteine biosynthetic process |
| I | 0005737 | cellular_component | cytoplasm |
| I | 0005829 | cellular_component | cytosol |
| I | 0006535 | biological_process | cysteine biosynthetic process from serine |
| I | 0008652 | biological_process | amino acid biosynthetic process |
| I | 0009001 | molecular_function | serine O-acetyltransferase activity |
| I | 0016740 | molecular_function | transferase activity |
| I | 0016746 | molecular_function | acyltransferase activity |
| I | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| I | 0019344 | biological_process | cysteine biosynthetic process |
| J | 0005737 | cellular_component | cytoplasm |
| J | 0005829 | cellular_component | cytosol |
| J | 0006535 | biological_process | cysteine biosynthetic process from serine |
| J | 0008652 | biological_process | amino acid biosynthetic process |
| J | 0009001 | molecular_function | serine O-acetyltransferase activity |
| J | 0016740 | molecular_function | transferase activity |
| J | 0016746 | molecular_function | acyltransferase activity |
| J | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| J | 0019344 | biological_process | cysteine biosynthetic process |
| K | 0005737 | cellular_component | cytoplasm |
| K | 0005829 | cellular_component | cytosol |
| K | 0006535 | biological_process | cysteine biosynthetic process from serine |
| K | 0008652 | biological_process | amino acid biosynthetic process |
| K | 0009001 | molecular_function | serine O-acetyltransferase activity |
| K | 0016740 | molecular_function | transferase activity |
| K | 0016746 | molecular_function | acyltransferase activity |
| K | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| K | 0019344 | biological_process | cysteine biosynthetic process |
| L | 0005737 | cellular_component | cytoplasm |
| L | 0005829 | cellular_component | cytosol |
| L | 0006535 | biological_process | cysteine biosynthetic process from serine |
| L | 0008652 | biological_process | amino acid biosynthetic process |
| L | 0009001 | molecular_function | serine O-acetyltransferase activity |
| L | 0016740 | molecular_function | transferase activity |
| L | 0016746 | molecular_function | acyltransferase activity |
| L | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| L | 0019344 | biological_process | cysteine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 274 |
| Chain | Residue |
| A | SER179 |
| A | LYS207 |
| A | HOH838 |
| B | SER179 |
| B | LYS207 |
| C | SER179 |
| C | LYS207 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACY A 275 |
| Chain | Residue |
| B | LYS126 |
| B | ILE130 |
| A | ASP96 |
| A | LYS97 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE CYS A 501 |
| Chain | Residue |
| A | GLY184 |
| A | ARG192 |
| A | HIS193 |
| A | HOH322 |
| A | HOH950 |
| C | ASP92 |
| C | PRO93 |
| C | ASP157 |
| C | HIS158 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE CYS A 276 |
| Chain | Residue |
| A | ASP92 |
| A | PRO93 |
| A | ALA94 |
| A | ASP157 |
| A | HIS158 |
| A | HOH282 |
| A | HOH283 |
| B | GLY184 |
| B | ARG192 |
| B | HIS193 |
| B | HOH897 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 274 |
| Chain | Residue |
| B | ASP96 |
| B | LYS97 |
| B | HOH441 |
| C | ALA127 |
| C | ILE130 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE CYS B 501 |
| Chain | Residue |
| B | ASP92 |
| B | PRO93 |
| B | ALA94 |
| B | ASP157 |
| B | HIS158 |
| B | HOH486 |
| C | GLY184 |
| C | ARG192 |
| C | HIS193 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PG5 C 274 |
| Chain | Residue |
| C | ALA0 |
| C | HIS76 |
| C | ARG83 |
| C | ARG91 |
| C | CYS152 |
| C | GLY153 |
| C | ASN172 |
| C | ASP173 |
| C | HOH520 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACY C 275 |
| Chain | Residue |
| A | ILE130 |
| C | ASP96 |
| C | LYS97 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE CYS D 501 |
| Chain | Residue |
| D | GLY184 |
| D | ARG192 |
| D | HIS193 |
| D | HOH279 |
| F | ASP92 |
| F | PRO93 |
| F | ASP157 |
| F | HIS158 |
| F | HOH288 |
| site_id | BC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE CYS D 274 |
| Chain | Residue |
| D | ASP92 |
| D | PRO93 |
| D | ALA94 |
| D | ASP157 |
| D | HIS158 |
| E | GLY184 |
| E | ARG192 |
| E | HIS193 |
| E | HOH1001 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL E 274 |
| Chain | Residue |
| E | LEU20 |
| E | ASP96 |
| E | LYS97 |
| E | HOH699 |
| F | LYS126 |
| F | ALA127 |
| site_id | BC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE CYS E 501 |
| Chain | Residue |
| E | ASP92 |
| E | PRO93 |
| E | ALA94 |
| E | ASP157 |
| E | HIS158 |
| E | HOH293 |
| E | HOH427 |
| F | GLY184 |
| F | ARG192 |
| F | HIS193 |
| site_id | BC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 F 274 |
| Chain | Residue |
| F | LYS207 |
| D | SER179 |
| D | GLY205 |
| D | LYS207 |
| E | SER179 |
| E | GLY205 |
| E | LYS207 |
| F | SER179 |
| F | GLY205 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL F 275 |
| Chain | Residue |
| D | LYS126 |
| D | ALA127 |
| F | LEU20 |
| F | ASP96 |
| F | LYS97 |
| F | HOH767 |
| F | HOH946 |
| site_id | BC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE CYS G 501 |
| Chain | Residue |
| G | ASP92 |
| G | PRO93 |
| G | ASP157 |
| G | HIS158 |
| G | HOH651 |
| H | GLY184 |
| H | ARG192 |
| H | HIS193 |
| H | HOH279 |
| H | HOH556 |
| site_id | BC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 H 274 |
| Chain | Residue |
| G | SER179 |
| G | GLY205 |
| G | LYS207 |
| H | SER179 |
| H | GLY205 |
| H | LYS207 |
| I | SER179 |
| I | LYS207 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL H 275 |
| Chain | Residue |
| H | ASP96 |
| H | LYS97 |
| I | ALA127 |
| I | ILE130 |
| I | HOH413 |
| site_id | BC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE CYS H 501 |
| Chain | Residue |
| H | ASP92 |
| H | PRO93 |
| H | ASP157 |
| H | HIS158 |
| H | HOH599 |
| I | GLY184 |
| I | ARG192 |
| I | HIS193 |
| site_id | CC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE CYS I 501 |
| Chain | Residue |
| G | GLY184 |
| G | ARG192 |
| G | HIS193 |
| I | ASP92 |
| I | PRO93 |
| I | ALA94 |
| I | ASP157 |
| I | HIS158 |
| I | HOH276 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL J 274 |
| Chain | Residue |
| J | ARG89 |
| J | ASP92 |
| J | PRO93 |
| J | VAL95 |
| J | ASP96 |
| J | HOH931 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACY J 275 |
| Chain | Residue |
| I | GLN123 |
| J | ASP124 |
| J | HOH397 |
| L | CYS23 |
| site_id | CC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACY J 276 |
| Chain | Residue |
| J | ASP96 |
| J | LYS97 |
| J | HOH286 |
| site_id | CC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE CYS J 501 |
| Chain | Residue |
| J | ASP92 |
| J | PRO93 |
| J | ALA94 |
| J | ASP157 |
| J | HIS158 |
| J | HOH888 |
| K | GLY184 |
| K | ARG192 |
| K | HIS193 |
| K | HOH286 |
| site_id | CC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 K 274 |
| Chain | Residue |
| I | SER29 |
| K | PRO59 |
| K | HOH293 |
| K | HOH844 |
| K | HOH967 |
| site_id | CC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 L 274 |
| Chain | Residue |
| J | SER179 |
| J | LYS207 |
| K | SER179 |
| K | LYS207 |
| L | SER179 |
| L | LYS207 |
| L | HOH822 |
| site_id | CC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG L 275 |
| Chain | Residue |
| J | TRP121 |
| J | HOH278 |
| L | LEU20 |
| L | ASP96 |
| L | LYS97 |
| L | HOH286 |
| site_id | CC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE CYS L 501 |
| Chain | Residue |
| J | GLY184 |
| J | ARG192 |
| J | HIS193 |
| L | ASP92 |
| L | PRO93 |
| L | ALA94 |
| L | ASP157 |
| L | HIS158 |
| L | HOH933 |
| site_id | DC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE CYS L 276 |
| Chain | Residue |
| K | ASP92 |
| K | ALA94 |
| K | ASP157 |
| K | HIS158 |
| K | HOH292 |
| L | GLY184 |
| L | ARG192 |
| L | HIS193 |
| L | HOH289 |
| L | HOH396 |
Functional Information from PROSITE/UniProt
| site_id | PS00101 |
| Number of Residues | 29 |
| Details | HEXAPEP_TRANSFERASES Hexapeptide-repeat containing-transferases signature. IGagAkIlgnIeVGrgAkIGagSvVlqsV |
| Chain | Residue | Details |
| A | ILE202-VAL230 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1lxa |
| Chain | Residue | Details |
| A | GLU166 |
| site_id | CSA10 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1lxa |
| Chain | Residue | Details |
| J | GLU166 |
| site_id | CSA11 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1lxa |
| Chain | Residue | Details |
| K | GLU166 |
| site_id | CSA12 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1lxa |
| Chain | Residue | Details |
| L | GLU166 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1lxa |
| Chain | Residue | Details |
| B | GLU166 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1lxa |
| Chain | Residue | Details |
| C | GLU166 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1lxa |
| Chain | Residue | Details |
| D | GLU166 |
| site_id | CSA5 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1lxa |
| Chain | Residue | Details |
| E | GLU166 |
| site_id | CSA6 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1lxa |
| Chain | Residue | Details |
| F | GLU166 |
| site_id | CSA7 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1lxa |
| Chain | Residue | Details |
| G | GLU166 |
| site_id | CSA8 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1lxa |
| Chain | Residue | Details |
| H | GLU166 |
| site_id | CSA9 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1lxa |
| Chain | Residue | Details |
| I | GLU166 |
