3GUE
Crystal Structure of UDP-glucose phosphorylase from Trypanosoma Brucei, (Tb10.389.0330)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003983 | molecular_function | UTP:glucose-1-phosphate uridylyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005977 | biological_process | glycogen metabolic process |
| A | 0006011 | biological_process | UDP-alpha-D-glucose metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0020015 | cellular_component | glycosome |
| A | 0031981 | cellular_component | nuclear lumen |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070569 | molecular_function | uridylyltransferase activity |
| A | 0097014 | cellular_component | ciliary plasm |
| B | 0003983 | molecular_function | UTP:glucose-1-phosphate uridylyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005977 | biological_process | glycogen metabolic process |
| B | 0006011 | biological_process | UDP-alpha-D-glucose metabolic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0020015 | cellular_component | glycosome |
| B | 0031981 | cellular_component | nuclear lumen |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0070569 | molecular_function | uridylyltransferase activity |
| B | 0097014 | cellular_component | ciliary plasm |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE UPG A 484 |
| Chain | Residue |
| A | LEU81 |
| A | ASN218 |
| A | GLY219 |
| A | ASP220 |
| A | GLY255 |
| A | GLY256 |
| A | GLU279 |
| A | PHE300 |
| A | ASN301 |
| A | ASN303 |
| A | PHE371 |
| A | ASN82 |
| A | LYS375 |
| A | GOL490 |
| A | HOH492 |
| A | HOH502 |
| A | HOH518 |
| A | HOH544 |
| A | HOH575 |
| A | HOH598 |
| A | HOH657 |
| A | HOH707 |
| A | GLY83 |
| A | GLY84 |
| A | MET130 |
| A | GLN161 |
| A | PRO187 |
| A | GLY189 |
| A | HIS190 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 485 |
| Chain | Residue |
| A | ARG212 |
| A | HOH499 |
| A | HOH509 |
| B | TYR150 |
| B | PHE153 |
| B | ASP154 |
| B | HOH581 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 486 |
| Chain | Residue |
| A | GLN75 |
| A | TYR213 |
| A | HIS235 |
| A | ASN308 |
| A | HOH775 |
| B | GLU151 |
| B | SER155 |
| B | HOH581 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 487 |
| Chain | Residue |
| A | LEU91 |
| A | ASN92 |
| A | GLY93 |
| A | PRO94 |
| A | GLU138 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 488 |
| Chain | Residue |
| A | SER290 |
| A | ASN293 |
| A | LYS296 |
| B | ARG74 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE DTU A 489 |
| Chain | Residue |
| A | CYS27 |
| A | PHE31 |
| A | GLN34 |
| A | VAL164 |
| A | PRO188 |
| A | ASP192 |
| A | THR195 |
| A | LEU347 |
| A | VAL349 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 490 |
| Chain | Residue |
| A | GLY189 |
| A | GLU348 |
| A | UPG484 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 484 |
| Chain | Residue |
| B | ASP410 |
| B | ASP412 |
| B | VAL441 |
| B | ARG442 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 485 |
| Chain | Residue |
| B | GLY86 |
| B | THR87 |
| B | GLY88 |
| B | LYS254 |
| B | LYS332 |
| B | UPG492 |
| B | HOH537 |
| B | HOH917 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 486 |
| Chain | Residue |
| B | THR342 |
| B | LYS343 |
| B | HOH720 |
| B | HOH738 |
| B | HOH748 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 487 |
| Chain | Residue |
| B | GLN169 |
| B | PRO331 |
| B | LYS332 |
| B | THR333 |
| B | LYS343 |
| B | HOH591 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 488 |
| Chain | Residue |
| B | HIS415 |
| B | GLY443 |
| B | LEU444 |
| B | ASN461 |
| B | LEU462 |
| B | LYS463 |
| site_id | BC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 489 |
| Chain | Residue |
| B | ASP192 |
| B | THR195 |
| B | VAL349 |
| B | HOH522 |
| B | CYS27 |
| B | PHE31 |
| B | GLN34 |
| B | VAL164 |
| B | PRO188 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PG4 B 490 |
| Chain | Residue |
| B | PRO126 |
| B | PHE127 |
| B | THR148 |
| B | LEU149 |
| B | ASP156 |
| B | TYR211 |
| B | HOH862 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 491 |
| Chain | Residue |
| B | SER378 |
| B | LEU411 |
| B | ASP412 |
| B | GLY413 |
| B | TYR416 |
| B | LYS417 |
| B | HOH767 |
| site_id | BC7 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE UPG B 492 |
| Chain | Residue |
| B | LEU81 |
| B | ASN82 |
| B | GLY83 |
| B | GLY84 |
| B | MET130 |
| B | GLN161 |
| B | PRO187 |
| B | GLY189 |
| B | HIS190 |
| B | ASN218 |
| B | GLY219 |
| B | ASP220 |
| B | LYS254 |
| B | GLY255 |
| B | GLY256 |
| B | GLU279 |
| B | PHE300 |
| B | ASN301 |
| B | ASN303 |
| B | PHE371 |
| B | LYS375 |
| B | SO4485 |
| B | HOH494 |
| B | HOH500 |
| B | HOH570 |
| B | HOH602 |
| B | HOH711 |
| B | HOH744 |
| B | HOH750 |
| B | HOH751 |
| B | HOH845 |
