3GQO
Crystal structure of macro domain of Venezuelan Equine Encephalitis virus in complex with ADP-ribose
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE APR A 167 |
| Chain | Residue |
| A | GLY9 |
| A | VAL33 |
| A | CYS34 |
| A | LEU108 |
| A | SER110 |
| A | THR111 |
| A | GLY112 |
| A | ILE113 |
| A | PHE114 |
| A | ARG144 |
| A | TRP148 |
| A | ASP10 |
| A | HOH199 |
| A | HOH279 |
| A | HOH281 |
| A | ILE11 |
| A | ALA22 |
| A | ALA23 |
| A | ASN24 |
| A | GLY30 |
| A | GLY31 |
| A | GLY32 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE APR B 167 |
| Chain | Residue |
| B | GLY9 |
| B | ASP10 |
| B | ILE11 |
| B | ALA22 |
| B | ASN24 |
| B | GLY30 |
| B | GLY31 |
| B | GLY32 |
| B | VAL33 |
| B | CYS34 |
| B | ALA36 |
| B | LEU108 |
| B | SER110 |
| B | THR111 |
| B | GLY112 |
| B | ILE113 |
| B | PHE114 |
| B | ARG144 |
| B | HOH179 |
| B | HOH191 |
| B | HOH205 |
| B | HOH229 |
| C | ASN117 |
| site_id | AC3 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE APR C 167 |
| Chain | Residue |
| C | GLY9 |
| C | ASP10 |
| C | ILE11 |
| C | ALA22 |
| C | ASN24 |
| C | GLY30 |
| C | GLY31 |
| C | GLY32 |
| C | VAL33 |
| C | CYS34 |
| C | ALA36 |
| C | LEU108 |
| C | SER110 |
| C | THR111 |
| C | GLY112 |
| C | ILE113 |
| C | PHE114 |
| C | HOH172 |
| C | HOH198 |
| C | HOH268 |
| site_id | AC4 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE APR D 167 |
| Chain | Residue |
| D | GLY9 |
| D | ASP10 |
| D | ILE11 |
| D | ALA22 |
| D | ASN24 |
| D | GLY30 |
| D | GLY31 |
| D | GLY32 |
| D | VAL33 |
| D | CYS34 |
| D | LEU108 |
| D | SER110 |
| D | THR111 |
| D | GLY112 |
| D | ILE113 |
| D | PHE114 |
| D | ARG144 |
| D | HOH192 |
| D | HOH197 |
| D | HOH200 |
| D | HOH208 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19386706 |
| Chain | Residue | Details |
| A | ASP10 | |
| A | GLY112 | |
| A | ILE113 | |
| A | PHE114 | |
| B | ASP10 | |
| B | GLY112 | |
| B | ILE113 | |
| B | PHE114 | |
| C | ASP10 | |
| C | GLY112 | |
| C | ILE113 | |
| C | PHE114 | |
| D | ASP10 | |
| D | GLY112 | |
| D | ILE113 | |
| D | PHE114 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q8JUX6 |
| Chain | Residue | Details |
| A | GLY32 | |
| B | ASN24 | |
| B | GLY32 | |
| A | ASN24 | |
| C | ASN24 | |
| C | GLY32 | |
| D | ASN24 | |
| D | GLY32 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | SITE: Cleavage; by protease nsP2 => ECO:0000250|UniProtKB:P03317 |
| Chain | Residue | Details |
| A | LYS0 | |
| B | LYS0 | |
| C | LYS0 | |
| D | LYS0 |
