Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005007 | molecular_function | fibroblast growth factor receptor activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005007 | molecular_function | fibroblast growth factor receptor activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
| C | 0004672 | molecular_function | protein kinase activity |
| C | 0004713 | molecular_function | protein tyrosine kinase activity |
| C | 0005007 | molecular_function | fibroblast growth factor receptor activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE GQL A 1 |
| Chain | Residue |
| A | HOH37 |
| A | GLU531 |
| A | ILE545 |
| A | GLU562 |
| A | TYR563 |
| A | ALA564 |
| A | LEU630 |
| A | ASP641 |
| A | HOH100 |
| A | HOH134 |
| A | LEU484 |
| A | GLY485 |
| A | GLU486 |
| A | VAL492 |
| A | ALA512 |
| A | LYS514 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GQL B 1 |
| Chain | Residue |
| B | HOH33 |
| B | HOH132 |
| B | LEU484 |
| B | GLY485 |
| B | VAL492 |
| B | LYS514 |
| B | ILE545 |
| B | GLU562 |
| B | TYR563 |
| B | ALA564 |
| B | LEU630 |
| B | ASP641 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GQL C 1 |
| Chain | Residue |
| C | LEU484 |
| C | GLY485 |
| C | VAL492 |
| C | ALA512 |
| C | LYS514 |
| C | GLU531 |
| C | ILE545 |
| C | GLU562 |
| C | TYR563 |
| C | ALA564 |
| C | LEU630 |
| C | ASP641 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 31 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGAFGQVVlAeaigldkdkpnrvtk...VAVK |
| Chain | Residue | Details |
| A | LEU484-LYS514 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. CIHrDLAARNVLV |
| Chain | Residue | Details |
| A | CYS619-VAL631 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | LEU624 | |
| B | ASP623 | |
| C | ASP623 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLY485 | |
| B | ASN568 | |
| B | ARG627 | |
| B | ASP641 | |
| C | LEU484 | |
| C | LYS514 | |
| C | GLU562 | |
| C | ASN568 | |
| C | ARG627 | |
| C | ASP641 | |
| A | MET515 | |
| A | TYR563 | |
| A | LEU569 | |
| A | ASN628 | |
| A | PHE642 | |
| B | LEU484 | |
| B | LYS514 | |
| B | GLU562 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | SITE: Mediates interaction with PLCG1 and SHB |
| Chain | Residue | Details |
| A | LEU767 | |
| B | TYR766 | |
| C | TYR766 | |
| Chain | Residue | Details |
| A | GLU464 | |
| A | CYS584 | |
| A | ASN586 | |
| B | TYR463 | |
| B | TYR583 | |
| B | TYR585 | |
| C | TYR463 | |
| C | TYR583 | |
| C | TYR585 | |
| Chain | Residue | Details |
| A | TYR654 | |
| A | LYS655 | |
| B | TYR653 | |
| B | TYR654 | |
| C | TYR653 | |
| C | TYR654 | |
| Chain | Residue | Details |
| A | MET731 | |
| B | TYR730 | |
| C | TYR730 | |
| Chain | Residue | Details |
| A | LEU767 | |
| B | TYR766 | |
| C | TYR766 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ARG627 | |
| A | ASP623 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | ARG627 | |
| B | ASP623 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| C | ARG627 | |
| C | ASP623 | |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ALA625 | |
| A | ASP623 | |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | ALA625 | |
| B | ASP623 | |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| C | ALA625 | |
| C | ASP623 | |
| site_id | CSA7 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ASN628 | |
| A | ALA625 | |
| A | ASP623 | |
| site_id | CSA8 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | ASN628 | |
| B | ALA625 | |
| B | ASP623 | |
| site_id | CSA9 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| C | ASN628 | |
| C | ALA625 | |
| C | ASP623 | |
