3GOD
Structural basis for DNase activity of a conserved protein implicated in CRISPR-mediated antiviral defense
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0004520 | molecular_function | DNA endonuclease activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0043571 | biological_process | maintenance of CRISPR repeat elements |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051607 | biological_process | defense response to virus |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0004520 | molecular_function | DNA endonuclease activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0043571 | biological_process | maintenance of CRISPR repeat elements |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051607 | biological_process | defense response to virus |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0004519 | molecular_function | endonuclease activity |
| C | 0004520 | molecular_function | DNA endonuclease activity |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0043571 | biological_process | maintenance of CRISPR repeat elements |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051607 | biological_process | defense response to virus |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0004519 | molecular_function | endonuclease activity |
| D | 0004520 | molecular_function | DNA endonuclease activity |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0043571 | biological_process | maintenance of CRISPR repeat elements |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0051607 | biological_process | defense response to virus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 325 |
| Chain | Residue |
| A | GLU190 |
| A | HIS254 |
| A | ASP268 |
| A | HOH451 |
| A | HOH526 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 326 |
| Chain | Residue |
| A | GLY87 |
| A | GLY216 |
| A | GLY218 |
| A | HOH542 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA A 327 |
| Chain | Residue |
| A | ASP307 |
| A | ASP311 |
| A | HOH509 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MN B 325 |
| Chain | Residue |
| B | GLU190 |
| B | HIS254 |
| B | ASP268 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA B 326 |
| Chain | Residue |
| B | ASP307 |
| B | ASP311 |
| B | HOH420 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 327 |
| Chain | Residue |
| B | GLY87 |
| B | GLY216 |
| B | GLY218 |
| B | HOH365 |
| B | HOH373 |
| B | HOH667 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MN C 325 |
| Chain | Residue |
| C | HIS254 |
| C | ASP268 |
| C | HOH506 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MN D 325 |
| Chain | Residue |
| D | HIS254 |
| D | ASP268 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19523907","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3GOD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
