3GOD

Structural basis for DNase activity of a conserved protein implicated in CRISPR-mediated antiviral defense

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004520	molecular_function	DNA endonuclease activity
A	0016787	molecular_function	hydrolase activity
A	0042802	molecular_function	identical protein binding
A	0043571	biological_process	maintenance of CRISPR repeat elements
A	0046872	molecular_function	metal ion binding
A	0051607	biological_process	defense response to virus
B	0003676	molecular_function	nucleic acid binding
B	0003677	molecular_function	DNA binding
B	0004518	molecular_function	nuclease activity
B	0004519	molecular_function	endonuclease activity
B	0004520	molecular_function	DNA endonuclease activity
B	0016787	molecular_function	hydrolase activity
B	0042802	molecular_function	identical protein binding
B	0043571	biological_process	maintenance of CRISPR repeat elements
B	0046872	molecular_function	metal ion binding
B	0051607	biological_process	defense response to virus
C	0003676	molecular_function	nucleic acid binding
C	0003677	molecular_function	DNA binding
C	0004518	molecular_function	nuclease activity
C	0004519	molecular_function	endonuclease activity
C	0004520	molecular_function	DNA endonuclease activity
C	0016787	molecular_function	hydrolase activity
C	0042802	molecular_function	identical protein binding
C	0043571	biological_process	maintenance of CRISPR repeat elements
C	0046872	molecular_function	metal ion binding
C	0051607	biological_process	defense response to virus
D	0003676	molecular_function	nucleic acid binding
D	0003677	molecular_function	DNA binding
D	0004518	molecular_function	nuclease activity
D	0004519	molecular_function	endonuclease activity
D	0004520	molecular_function	DNA endonuclease activity
D	0016787	molecular_function	hydrolase activity
D	0042802	molecular_function	identical protein binding
D	0043571	biological_process	maintenance of CRISPR repeat elements
D	0046872	molecular_function	metal ion binding
D	0051607	biological_process	defense response to virus

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN A 325

Chain	Residue
A	GLU190
A	HIS254
A	ASP268
A	HOH451
A	HOH526

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA A 326

Chain	Residue
A	GLY87
A	GLY216
A	GLY218
A	HOH542

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA A 327

Chain	Residue
A	ASP307
A	ASP311
A	HOH509

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MN B 325

Chain	Residue
B	GLU190
B	HIS254
B	ASP268

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA B 326

Chain	Residue
B	ASP307
B	ASP311
B	HOH420

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site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA B 327

Chain	Residue
B	GLY87
B	GLY216
B	GLY218
B	HOH365
B	HOH373
B	HOH667

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site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MN C 325

Chain	Residue
C	HIS254
C	ASP268
C	HOH506

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site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MN D 325

Chain	Residue
D	HIS254
D	ASP268

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19523907","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3GOD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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