Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3GLC

Crystal Structure of E. coli LsrF in complex with Ribose-5-phosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004332	molecular_function	fructose-bisphosphate aldolase activity
A	0005737	cellular_component	cytoplasm
A	0016740	molecular_function	transferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
A	0016829	molecular_function	lyase activity
B	0004332	molecular_function	fructose-bisphosphate aldolase activity
B	0005737	cellular_component	cytoplasm
B	0016740	molecular_function	transferase activity
B	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
B	0016829	molecular_function	lyase activity
C	0004332	molecular_function	fructose-bisphosphate aldolase activity
C	0005737	cellular_component	cytoplasm
C	0016740	molecular_function	transferase activity
C	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
C	0016829	molecular_function	lyase activity
D	0004332	molecular_function	fructose-bisphosphate aldolase activity
D	0005737	cellular_component	cytoplasm
D	0016740	molecular_function	transferase activity
D	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
D	0016829	molecular_function	lyase activity
E	0004332	molecular_function	fructose-bisphosphate aldolase activity
E	0005737	cellular_component	cytoplasm
E	0016740	molecular_function	transferase activity
E	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
E	0016829	molecular_function	lyase activity
F	0004332	molecular_function	fructose-bisphosphate aldolase activity
F	0005737	cellular_component	cytoplasm
F	0016740	molecular_function	transferase activity
F	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
F	0016829	molecular_function	lyase activity
G	0004332	molecular_function	fructose-bisphosphate aldolase activity
G	0005737	cellular_component	cytoplasm
G	0016740	molecular_function	transferase activity
G	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
G	0016829	molecular_function	lyase activity
H	0004332	molecular_function	fructose-bisphosphate aldolase activity
H	0005737	cellular_component	cytoplasm
H	0016740	molecular_function	transferase activity
H	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
H	0016829	molecular_function	lyase activity
I	0004332	molecular_function	fructose-bisphosphate aldolase activity
I	0005737	cellular_component	cytoplasm
I	0016740	molecular_function	transferase activity
I	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
I	0016829	molecular_function	lyase activity
J	0004332	molecular_function	fructose-bisphosphate aldolase activity
J	0005737	cellular_component	cytoplasm
J	0016740	molecular_function	transferase activity
J	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
J	0016829	molecular_function	lyase activity
K	0004332	molecular_function	fructose-bisphosphate aldolase activity
K	0005737	cellular_component	cytoplasm
K	0016740	molecular_function	transferase activity
K	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
K	0016829	molecular_function	lyase activity
L	0004332	molecular_function	fructose-bisphosphate aldolase activity
L	0005737	cellular_component	cytoplasm
L	0016740	molecular_function	transferase activity
L	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
L	0016829	molecular_function	lyase activity
M	0004332	molecular_function	fructose-bisphosphate aldolase activity
M	0005737	cellular_component	cytoplasm
M	0016740	molecular_function	transferase activity
M	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
M	0016829	molecular_function	lyase activity
N	0004332	molecular_function	fructose-bisphosphate aldolase activity
N	0005737	cellular_component	cytoplasm
N	0016740	molecular_function	transferase activity
N	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
N	0016829	molecular_function	lyase activity
O	0004332	molecular_function	fructose-bisphosphate aldolase activity
O	0005737	cellular_component	cytoplasm
O	0016740	molecular_function	transferase activity
O	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
O	0016829	molecular_function	lyase activity
P	0004332	molecular_function	fructose-bisphosphate aldolase activity
P	0005737	cellular_component	cytoplasm
P	0016740	molecular_function	transferase activity
P	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
P	0016829	molecular_function	lyase activity
Q	0004332	molecular_function	fructose-bisphosphate aldolase activity
Q	0005737	cellular_component	cytoplasm
Q	0016740	molecular_function	transferase activity
Q	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
Q	0016829	molecular_function	lyase activity
R	0004332	molecular_function	fructose-bisphosphate aldolase activity
R	0005737	cellular_component	cytoplasm
R	0016740	molecular_function	transferase activity
R	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
R	0016829	molecular_function	lyase activity
S	0004332	molecular_function	fructose-bisphosphate aldolase activity
S	0005737	cellular_component	cytoplasm
S	0016740	molecular_function	transferase activity
S	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
S	0016829	molecular_function	lyase activity
T	0004332	molecular_function	fructose-bisphosphate aldolase activity
T	0005737	cellular_component	cytoplasm
T	0016740	molecular_function	transferase activity
T	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
T	0016829	molecular_function	lyase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE R5P A 400

Chain	Residue
A	ASP57
A	ARG254
A	HIS58
A	GLN141
A	LYS203
A	GLY226
A	GLY227
A	ASP251
A	MET252
A	GLY253

site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE R5P B 400

Chain	Residue
B	ASP57
B	HIS58
B	GLN141
B	LYS203
B	ALA225
B	GLY226
B	GLY227
B	ASP251
B	MET252
B	GLY253
B	ARG254

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE R5P C 400

Chain	Residue
C	ASP57
C	HIS58
C	LYS203
C	ALA225
C	GLY226
C	GLY227
C	ASP251
C	MET252
C	GLY253
C	ARG254

site_id	AC4
Number of Residues	12
Details	BINDING SITE FOR RESIDUE R5P D 400

Chain	Residue
D	ASP57
D	HIS58
D	ARG107
D	GLN141
D	LYS203
D	ALA225
D	GLY226
D	GLY227
D	ASP251
D	MET252
D	GLY253
D	ARG254

site_id	AC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE R5P E 400

Chain	Residue
E	ASP57
E	HIS58
E	GLN141
E	LYS203
E	ALA225
E	GLY226
E	GLY227
E	ASP251
E	MET252
E	GLY253
E	ARG254

site_id	AC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE R5P F 400

Chain	Residue
F	ASP57
F	HIS58
F	LYS203
F	ALA225
F	GLY226
F	GLY227
F	ASP251
F	MET252
F	GLY253
F	ARG254

site_id	AC7
Number of Residues	11
Details	BINDING SITE FOR RESIDUE R5P G 400

Chain	Residue
G	ASP57
G	HIS58
G	GLN141
G	LYS203
G	ALA225
G	GLY226
G	GLY227
G	ASP251
G	MET252
G	GLY253
G	ARG254

site_id	AC8
Number of Residues	11
Details	BINDING SITE FOR RESIDUE R5P H 400

Chain	Residue
H	ASP57
H	HIS58
H	ARG107
H	LYS203
H	ALA225
H	GLY226
H	GLY227
H	ASP251
H	MET252
H	GLY253
H	ARG254

site_id	AC9
Number of Residues	10
Details	BINDING SITE FOR RESIDUE R5P I 400

Chain	Residue
I	ASP57
I	HIS58
I	GLN141
I	LYS203
I	GLY226
I	GLY227
I	ASP251
I	MET252
I	GLY253
I	ARG254

site_id	BC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE R5P J 400

Chain	Residue
J	LYS203
J	GLY226
J	GLY227
J	ASP251
J	MET252
J	GLY253
J	ARG254
J	ASP57
J	HIS58
J	ARG107

site_id	BC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE R5P K 400

Chain	Residue
K	ASP57
K	HIS58
K	GLN141
K	LYS203
K	ALA225
K	GLY226
K	GLY227
K	ASP251
K	MET252
K	GLY253
K	ARG254

site_id	BC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE R5P L 400

Chain	Residue
L	ASP57
L	HIS58
L	GLN141
L	LYS203
L	ALA225
L	GLY226
L	GLY227
L	ASP251
L	MET252
L	GLY253
L	ARG254

site_id	BC4
Number of Residues	12
Details	BINDING SITE FOR RESIDUE R5P M 400

Chain	Residue
M	ASP57
M	HIS58
M	ARG107
M	GLN141
M	LYS203
M	ALA225
M	GLY226
M	GLY227
M	ASP251
M	MET252
M	GLY253
M	ARG254

site_id	BC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE R5P N 400

Chain	Residue
N	ASP57
N	HIS58
N	ARG107
N	GLN141
N	LYS203
N	GLY226
N	GLY227
N	ASP251
N	MET252
N	GLY253
N	ARG254

site_id	BC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE R5P O 400

Chain	Residue
O	ASP57
O	HIS58
O	ARG107
O	LYS203
O	GLY226
O	GLY227
O	ASP251
O	MET252
O	GLY253
O	ARG254

site_id	BC7
Number of Residues	11
Details	BINDING SITE FOR RESIDUE R5P P 400

Chain	Residue
P	ASP57
P	HIS58
P	ARG107
P	LYS203
P	ALA225
P	GLY226
P	GLY227
P	ASP251
P	MET252
P	GLY253
P	ARG254

site_id	BC8
Number of Residues	10
Details	BINDING SITE FOR RESIDUE R5P Q 400

Chain	Residue
Q	ASP57
Q	HIS58
Q	GLN141
Q	LYS203
Q	GLY226
Q	GLY227
Q	ASP251
Q	MET252
Q	GLY253
Q	ARG254

site_id	BC9
Number of Residues	9
Details	BINDING SITE FOR RESIDUE R5P R 400

Chain	Residue
R	ASP57
R	HIS58
R	LYS203
R	GLY226
R	GLY227
R	ASP251
R	MET252
R	GLY253
R	ARG254

site_id	CC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE R5P S 400

Chain	Residue
S	ASP57
S	HIS58
S	GLN141
S	LYS203
S	ALA225
S	GLY226
S	GLY227
S	ASP251
S	MET252
S	GLY253
S	ARG254

site_id	CC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE R5P T 400

Chain	Residue
T	ASP57
T	HIS58
T	ARG107
T	GLN141
T	LYS203
T	ALA225
T	GLY226
T	GLY227
T	ASP251
T	MET252
T	GLY253
T	ARG254

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	ACT_SITE: Schiff-base intermediate with substrate => ECO:0000255\|HAMAP-Rule:MF_02052, ECO:0000269\|PubMed:25225400

Chain	Residue	Details
A	LYS203
J	LYS203
K	LYS203
L	LYS203
M	LYS203
N	LYS203
O	LYS203
P	LYS203
Q	LYS203
R	LYS203
S	LYS203
B	LYS203
T	LYS203
C	LYS203
D	LYS203
E	LYS203
F	LYS203
G	LYS203
H	LYS203
I	LYS203

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)