3GK0
Crystal structure of pyridoxal phosphate biosynthetic protein from Burkholderia pseudomallei
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008615 | biological_process | pyridoxine biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016769 | molecular_function | transferase activity, transferring nitrogenous groups |
| A | 0033856 | molecular_function | pyridoxine 5'-phosphate synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008615 | biological_process | pyridoxine biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016769 | molecular_function | transferase activity, transferring nitrogenous groups |
| B | 0033856 | molecular_function | pyridoxine 5'-phosphate synthase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008615 | biological_process | pyridoxine biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016769 | molecular_function | transferase activity, transferring nitrogenous groups |
| C | 0033856 | molecular_function | pyridoxine 5'-phosphate synthase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008615 | biological_process | pyridoxine biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016769 | molecular_function | transferase activity, transferring nitrogenous groups |
| D | 0033856 | molecular_function | pyridoxine 5'-phosphate synthase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0008615 | biological_process | pyridoxine biosynthetic process |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016769 | molecular_function | transferase activity, transferring nitrogenous groups |
| E | 0033856 | molecular_function | pyridoxine 5'-phosphate synthase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0008615 | biological_process | pyridoxine biosynthetic process |
| F | 0016740 | molecular_function | transferase activity |
| F | 0016769 | molecular_function | transferase activity, transferring nitrogenous groups |
| F | 0033856 | molecular_function | pyridoxine 5'-phosphate synthase activity |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0008615 | biological_process | pyridoxine biosynthetic process |
| G | 0016740 | molecular_function | transferase activity |
| G | 0016769 | molecular_function | transferase activity, transferring nitrogenous groups |
| G | 0033856 | molecular_function | pyridoxine 5'-phosphate synthase activity |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0008615 | biological_process | pyridoxine biosynthetic process |
| H | 0016740 | molecular_function | transferase activity |
| H | 0016769 | molecular_function | transferase activity, transferring nitrogenous groups |
| H | 0033856 | molecular_function | pyridoxine 5'-phosphate synthase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 B 258 |
| Chain | Residue |
| B | THR29 |
| B | TYR31 |
| B | HOH271 |
| B | HOH430 |
| E | HIS203 |
| E | HIS223 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DXP C 258 |
| Chain | Residue |
| C | HIS228 |
| C | HOH283 |
| H | THR29 |
| H | TYR31 |
| C | TYR204 |
| C | HIS223 |
| C | ALA224 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 D 258 |
| Chain | Residue |
| D | HIS203 |
| D | HIS223 |
| D | ALA224 |
| D | HOH267 |
| F | THR29 |
| F | TYR31 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 E 258 |
| Chain | Residue |
| B | HIS203 |
| B | HIS223 |
| E | THR29 |
| E | TYR31 |
| E | HOH266 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE DXP F 258 |
| Chain | Residue |
| D | THR29 |
| D | TYR31 |
| F | TYR204 |
| F | HIS223 |
| F | ALA224 |
| F | HIS228 |
| F | HOH287 |
| F | HOH342 |
| F | HOH799 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 G 258 |
| Chain | Residue |
| A | HIS203 |
| A | HIS223 |
| A | ALA224 |
| G | THR29 |
| G | HOH271 |
| G | HOH442 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE DXP G 259 |
| Chain | Residue |
| A | THR29 |
| A | TYR31 |
| G | HIS203 |
| G | HIS223 |
| G | ALA224 |
| G | HIS228 |
| G | HOH267 |
| G | HOH273 |
| G | HOH850 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 H 258 |
| Chain | Residue |
| C | THR29 |
| C | TYR31 |
| H | HIS203 |
| H | ALA224 |
| H | HOH269 |
| H | HOH270 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00279 |
| Chain | Residue | Details |
| A | HIS52 | |
| E | GLU79 | |
| F | HIS52 | |
| F | GLU79 | |
| G | HIS52 | |
| G | GLU79 | |
| H | HIS52 | |
| H | GLU79 | |
| A | GLU79 | |
| B | HIS52 | |
| B | GLU79 | |
| C | HIS52 | |
| C | GLU79 | |
| D | HIS52 | |
| D | GLU79 | |
| E | HIS52 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00279 |
| Chain | Residue | Details |
| A | HIS200 | |
| B | HIS200 | |
| C | HIS200 | |
| D | HIS200 | |
| E | HIS200 | |
| F | HIS200 | |
| G | HIS200 | |
| H | HIS200 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 64 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00279 |
| Chain | Residue | Details |
| A | ASN16 | |
| B | ASP18 | |
| B | ARG27 | |
| B | ARG54 | |
| B | HIS59 | |
| B | THR109 | |
| B | GLY201 | |
| B | GLY222 | |
| C | ASN16 | |
| C | ASP18 | |
| C | ARG27 | |
| A | ASP18 | |
| C | ARG54 | |
| C | HIS59 | |
| C | THR109 | |
| C | GLY201 | |
| C | GLY222 | |
| D | ASN16 | |
| D | ASP18 | |
| D | ARG27 | |
| D | ARG54 | |
| D | HIS59 | |
| A | ARG27 | |
| D | THR109 | |
| D | GLY201 | |
| D | GLY222 | |
| E | ASN16 | |
| E | ASP18 | |
| E | ARG27 | |
| E | ARG54 | |
| E | HIS59 | |
| E | THR109 | |
| E | GLY201 | |
| A | ARG54 | |
| E | GLY222 | |
| F | ASN16 | |
| F | ASP18 | |
| F | ARG27 | |
| F | ARG54 | |
| F | HIS59 | |
| F | THR109 | |
| F | GLY201 | |
| F | GLY222 | |
| G | ASN16 | |
| A | HIS59 | |
| G | ASP18 | |
| G | ARG27 | |
| G | ARG54 | |
| G | HIS59 | |
| G | THR109 | |
| G | GLY201 | |
| G | GLY222 | |
| H | ASN16 | |
| H | ASP18 | |
| H | ARG27 | |
| A | THR109 | |
| H | ARG54 | |
| H | HIS59 | |
| H | THR109 | |
| H | GLY201 | |
| H | GLY222 | |
| A | GLY201 | |
| A | GLY222 | |
| B | ASN16 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00279 |
| Chain | Residue | Details |
| A | GLU160 | |
| B | GLU160 | |
| C | GLU160 | |
| D | GLU160 | |
| E | GLU160 | |
| F | GLU160 | |
| G | GLU160 | |
| H | GLU160 |
