Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016920 | molecular_function | pyroglutamyl-peptidase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016920 | molecular_function | pyroglutamyl-peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 213 |
| Chain | Residue |
| A | GLN68 |
| A | CYS141 |
| A | HIS165 |
| A | ACY214 |
| B | THR211 |
| B | GLU212 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACY A 214 |
| Chain | Residue |
| A | GLY67 |
| A | GLN68 |
| A | CYS141 |
| A | ZN213 |
| B | GLU212 |
| A | PHE8 |
| A | PHE11 |
| A | ASN17 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PG4 A 215 |
| Chain | Residue |
| A | ASN73 |
| A | GLY127 |
| A | LEU128 |
| A | PRO129 |
| A | GLY130 |
| A | HOH424 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PG4 A 216 |
| Chain | Residue |
| A | ASN83 |
| A | ASP99 |
| A | GLN100 |
| A | ALA101 |
| A | LEU104 |
| A | HOH310 |
| A | HOH340 |
| A | HOH369 |
| A | HOH545 |
| B | PHE111 |
| B | HOH507 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 217 |
| Chain | Residue |
| A | ASP94 |
| A | GLN96 |
| A | PRO115 |
| A | ALA118 |
| A | ALA197 |
| A | SER199 |
| A | LEU204 |
| A | HOH546 |
| A | HOH547 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN B 213 |
| Chain | Residue |
| A | THR211 |
| A | GLU212 |
| B | GLN68 |
| B | CYS141 |
| B | HIS165 |
| B | ACY214 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACY B 214 |
| Chain | Residue |
| A | GLU212 |
| B | PHE8 |
| B | PHE11 |
| B | ASN17 |
| B | GLY67 |
| B | GLN68 |
| B | CYS141 |
| B | ZN213 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PEG B 215 |
| Chain | Residue |
| B | SER112 |
| B | ASN113 |
| B | LEU114 |
| B | PRO115 |
| B | VAL116 |
| B | ASP201 |
| B | ASP203 |
| B | HOH280 |
| B | HOH284 |
| B | HOH314 |
| B | HOH480 |
| B | HOH492 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PG4 B 216 |
| Chain | Residue |
| B | ASN73 |
| B | GLY127 |
| B | LEU128 |
| B | PRO129 |
| B | GLY130 |
| B | HOH392 |
| site_id | BC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 217 |
| Chain | Residue |
| B | LEU55 |
| B | ASN58 |
| B | HIS59 |
| B | TYR60 |
| B | TYR156 |
| B | HOH245 |
| B | HOH409 |
| B | HOH413 |
| B | HOH591 |
Functional Information from PROSITE/UniProt
| site_id | PS01333 |
| Number of Residues | 17 |
| Details | PYRASE_GLU Pyrrolidone-carboxylate peptidase glutamic acid active site. GqaGgrnaITpERVAiN |
| Chain | Residue | Details |
| A | GLY67-ASN83 | |
| site_id | PS01334 |
| Number of Residues | 15 |
| Details | PYRASE_CYS Pyrrolidone-carboxylate peptidase cysteine active site. LpGaLSnSAGtFVCN |
| Chain | Residue | Details |
| A | LEU128-ASN142 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00417","evidenceCode":"ECO:0000255"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1aug |
| Chain | Residue | Details |
| A | CYS141 | |
| A | ARG88 | |
| A | GLU78 | |
| A | HIS165 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1aug |
| Chain | Residue | Details |
| B | CYS141 | |
| B | ARG88 | |
| B | GLU78 | |
| B | HIS165 | |
