Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| D | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
| E | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| E | 0006508 | biological_process | proteolysis |
| F | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| F | 0006508 | biological_process | proteolysis |
| G | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| G | 0006508 | biological_process | proteolysis |
| H | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| H | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE GGX H 1001 |
| Chain | Residue |
| G | ARG8 |
| H | ASP25 |
| H | GLY27 |
| H | ALA28 |
| H | ASP29 |
| H | GLY48 |
| H | GLY49 |
| H | VAL82 |
| G | LEU23 |
| G | ASP25 |
| G | GLY27 |
| G | ASP29 |
| G | GLY48 |
| G | GLY49 |
| G | PRO81 |
| H | ARG8 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE GGX B 1002 |
| Chain | Residue |
| A | ARG8 |
| A | LEU23 |
| A | ASP25 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | GLY48 |
| A | GLY49 |
| A | PRO81 |
| B | ARG8 |
| B | LEU23 |
| B | ASP25 |
| B | GLY27 |
| B | ASP29 |
| B | GLY48 |
| B | GLY49 |
| B | ILE50 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE GGX E 1003 |
| Chain | Residue |
| E | ARG8 |
| E | ASP25 |
| E | GLY27 |
| E | ALA28 |
| E | ASP29 |
| E | GLY48 |
| E | GLY49 |
| E | ILE50 |
| E | VAL82 |
| F | ARG8 |
| F | ASP25 |
| F | GLY27 |
| F | ALA28 |
| F | ASP29 |
| F | GLY48 |
| F | GLY49 |
| F | ILE50 |
| F | PRO81 |
| F | ILE84 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE GGX C 1004 |
| Chain | Residue |
| C | ARG8 |
| C | ASP25 |
| C | GLY27 |
| C | ALA28 |
| C | ASP29 |
| C | GLY48 |
| C | GLY49 |
| C | ILE84 |
| D | ARG8 |
| D | LEU23 |
| D | ASP25 |
| D | GLY27 |
| D | ALA28 |
| D | ASP29 |
| D | GLY48 |
| D | GLY49 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVL |
| Chain | Residue | Details |
| A | ALA22-LEU33 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI2 |
| Number of Residues | 80 |
| Details | Region: {"description":"Dimerization of protease","evidences":[{"source":"UniProtKB","id":"P04585","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Active site: {"description":"For protease activity; shared with dimeric partner","evidences":[{"source":"PROSITE-ProRule","id":"PRU10094","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12924029","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| A | THR26 | |
| site_id | CSA10 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| B | ASP25 | |
| site_id | CSA11 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| C | ASP25 | |
| site_id | CSA12 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| D | ASP25 | |
| site_id | CSA13 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| E | ASP25 | |
| site_id | CSA14 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| F | ASP25 | |
| site_id | CSA15 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| G | ASP25 | |
| site_id | CSA16 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| H | ASP25 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| B | ASP25 | |
| B | THR26 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| C | ASP25 | |
| C | THR26 | |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| D | ASP25 | |
| D | THR26 | |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| E | ASP25 | |
| E | THR26 | |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| F | ASP25 | |
| F | THR26 | |
| site_id | CSA7 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| G | ASP25 | |
| G | THR26 | |
| site_id | CSA8 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| H | ASP25 | |
| H | THR26 | |
| site_id | CSA9 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
