3GBO

Crystal structure of BmooMPalpha-I, a non-hemorrhagic metalloproteinase isolated from Bothrops moojeni snake venom

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004222	molecular_function	metalloendopeptidase activity
A	0005576	cellular_component	extracellular region
A	0005886	cellular_component	plasma membrane
A	0006508	biological_process	proteolysis
A	0008237	molecular_function	metallopeptidase activity
A	0035821	biological_process	modulation of process of another organism
A	0046872	molecular_function	metal ion binding
A	0090729	molecular_function	toxin activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 301

Chain	Residue
A	GLU7
A	ASP91
A	CYS195
A	ASN198
A	HOH405
A	HOH410

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN A 302

Chain	Residue
A	HOH531
A	HOH543
A	HOH544
A	HIS140
A	HIS144
A	HIS150

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Functional Information from PROSITE/UniProt

site_id	PS00142
Number of Residues	10
Details	ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TMAHELGHNL

Chain	Residue	Details
A	THR137-LEU146

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P83512, ECO:0000255|PROSITE-ProRule:PRU00276, ECO:0000255|PROSITE-ProRule:PRU10095

Chain	Residue	Details
A	ASN145

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:19706302, ECO:0007744|PDB:3GBO

Chain	Residue	Details
A	VAL11
A	LEU95
A	HIS144
A	MET148
A	GLN154
A	GLU199

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