3G8A

T. thermophilus 16S rRNA G527 methyltransferase in complex with AdoHcy in space group P61

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006364	biological_process	rRNA processing
A	0008168	molecular_function	methyltransferase activity
A	0008649	molecular_function	rRNA methyltransferase activity
A	0031167	biological_process	rRNA methylation
A	0032259	biological_process	methylation
A	0070043	molecular_function	rRNA (guanine-N7-)-methyltransferase activity
A	0070476	biological_process	rRNA (guanine-N7)-methylation
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006364	biological_process	rRNA processing
B	0008168	molecular_function	methyltransferase activity
B	0008649	molecular_function	rRNA methyltransferase activity
B	0031167	biological_process	rRNA methylation
B	0032259	biological_process	methylation
B	0070043	molecular_function	rRNA (guanine-N7-)-methyltransferase activity
B	0070476	biological_process	rRNA (guanine-N7)-methylation
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006364	biological_process	rRNA processing
C	0008168	molecular_function	methyltransferase activity
C	0008649	molecular_function	rRNA methyltransferase activity
C	0031167	biological_process	rRNA methylation
C	0032259	biological_process	methylation
C	0070043	molecular_function	rRNA (guanine-N7-)-methyltransferase activity
C	0070476	biological_process	rRNA (guanine-N7)-methylation
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006364	biological_process	rRNA processing
D	0008168	molecular_function	methyltransferase activity
D	0008649	molecular_function	rRNA methyltransferase activity
D	0031167	biological_process	rRNA methylation
D	0032259	biological_process	methylation
D	0070043	molecular_function	rRNA (guanine-N7-)-methyltransferase activity
D	0070476	biological_process	rRNA (guanine-N7)-methylation
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006364	biological_process	rRNA processing
E	0008168	molecular_function	methyltransferase activity
E	0008649	molecular_function	rRNA methyltransferase activity
E	0031167	biological_process	rRNA methylation
E	0032259	biological_process	methylation
E	0070043	molecular_function	rRNA (guanine-N7-)-methyltransferase activity
E	0070476	biological_process	rRNA (guanine-N7)-methylation
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006364	biological_process	rRNA processing
F	0008168	molecular_function	methyltransferase activity
F	0008649	molecular_function	rRNA methyltransferase activity
F	0031167	biological_process	rRNA methylation
F	0032259	biological_process	methylation
F	0070043	molecular_function	rRNA (guanine-N7-)-methyltransferase activity
F	0070476	biological_process	rRNA (guanine-N7)-methylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE SAH A 303

Chain	Residue
A	GLY88
A	ARG138
A	ALA139
A	GLU140
A	ARG158
A	ALA159
A	HOH310
A	HOH475
A	THR89
A	GLY90
A	PHE93
A	ASP111
A	ALA112
A	THR113
A	LYS116
A	GLY137

---

site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE SAH B 303

Chain	Residue
B	GLY88
B	THR89
B	GLY90
B	PHE93
B	ASP111
B	ALA112
B	THR113
B	GLY137
B	ARG138
B	ALA139
B	GLU140
B	ARG158
B	HOH336
B	HOH435
B	HOH452

---

site_id	AC3
Number of Residues	15
Details	BINDING SITE FOR RESIDUE SAH C 303

Chain	Residue
C	GLY88
C	THR89
C	GLY90
C	PHE93
C	ASP111
C	ALA112
C	THR113
C	GLY137
C	ARG138
C	ALA139
C	GLU140
C	ARG158
C	ALA159
C	HOH322
C	HOH378

---

site_id	AC4
Number of Residues	17
Details	BINDING SITE FOR RESIDUE SAH D 303

Chain	Residue
D	GLY88
D	THR89
D	GLY90
D	PHE93
D	ASP111
D	ALA112
D	THR113
D	LYS116
D	GLY137
D	ARG138
D	ALA139
D	GLU140
D	ARG158
D	ALA159
D	HOH338
D	HOH411
D	HOH518

---

site_id	AC5
Number of Residues	17
Details	BINDING SITE FOR RESIDUE SAH E 303

Chain	Residue
E	GLY88
E	THR89
E	GLY90
E	PHE93
E	ASP111
E	ALA112
E	THR113
E	GLY137
E	ARG138
E	ALA139
E	GLU140
E	ARG158
E	ALA159
E	HOH307
E	HOH333
E	HOH466
E	HOH471

---

site_id	AC6
Number of Residues	14
Details	BINDING SITE FOR RESIDUE SAH F 303

Chain	Residue
F	GLY88
F	THR89
F	GLY90
F	PHE93
F	ASP111
F	ALA112
F	THR113
F	GLY137
F	ARG138
F	ALA139
F	GLU140
F	ARG158
F	HOH326
F	HOH434

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	30
Details	BINDING:

Chain	Residue	Details
A	GLY88
B	ARG158
C	GLY88
C	PHE93
C	ASP111
C	ALA139
C	ARG158
D	GLY88
D	PHE93
D	ASP111
D	ALA139
A	PHE93
D	ARG158
E	GLY88
E	PHE93
E	ASP111
E	ALA139
E	ARG158
F	GLY88
F	PHE93
F	ASP111
F	ALA139
A	ASP111
F	ARG158
A	ALA139
A	ARG158
B	GLY88
B	PHE93
B	ASP111
B	ALA139

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