3G3F
Crystal structure of the GluR6 ligand binding domain dimer with glutamate and NaCl at 1.38 Angstrom resolution
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GLU A 260 |
| Chain | Residue |
| A | TYR61 |
| A | HOH268 |
| A | HOH269 |
| A | HOH273 |
| A | HOH348 |
| A | PRO89 |
| A | LEU90 |
| A | ALA91 |
| A | ARG96 |
| A | GLY141 |
| A | ALA142 |
| A | THR143 |
| A | GLU191 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 261 |
| Chain | Residue |
| A | LYS104 |
| A | ARG228 |
| A | HOH386 |
| B | LYS104 |
| B | ARG228 |
| B | HOH387 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 262 |
| Chain | Residue |
| A | GLU97 |
| A | ILE100 |
| A | ASP101 |
| A | MET223 |
| A | HOH378 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IPA A 263 |
| Chain | Residue |
| A | GLU240 |
| B | TYR94 |
| B | HOH343 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GLU B 260 |
| Chain | Residue |
| B | TYR61 |
| B | PRO89 |
| B | LEU90 |
| B | ALA91 |
| B | ARG96 |
| B | GLY141 |
| B | ALA142 |
| B | THR143 |
| B | GLU191 |
| B | HOH270 |
| B | HOH274 |
| B | HOH296 |
| B | HOH391 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA B 261 |
| Chain | Residue |
| B | GLU97 |
| B | ILE100 |
| B | ASP101 |
| B | MET223 |
| B | HOH469 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA B 262 |
| Chain | Residue |
| B | SER22 |
| B | HOH426 |
| B | HOH479 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 263 |
| Chain | Residue |
| B | ILE11 |
| B | LEU12 |
| B | HOH341 |
| B | HOH364 |
| B | HOH416 |
| B | HOH459 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IPA B 264 |
| Chain | Residue |
| A | TYR94 |
| A | HOH478 |
| B | GLU240 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15721240","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17115050","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1S50","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1S7Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2I0B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2I0C","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"15677325","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8163463","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
