3G2U
VHS Domain of human GGA1 complexed with Sotilin C-terminal Peptide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005802 | cellular_component | trans-Golgi network |
| A | 0006886 | biological_process | intracellular protein transport |
| A | 0031267 | molecular_function | small GTPase binding |
| A | 0035091 | molecular_function | phosphatidylinositol binding |
| A | 0043130 | molecular_function | ubiquitin binding |
| B | 0005802 | cellular_component | trans-Golgi network |
| B | 0006886 | biological_process | intracellular protein transport |
| B | 0031267 | molecular_function | small GTPase binding |
| B | 0035091 | molecular_function | phosphatidylinositol binding |
| B | 0043130 | molecular_function | ubiquitin binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD A 148 |
| Chain | Residue |
| A | LEU50 |
| B | GLN59 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD A 149 |
| Chain | Residue |
| A | PRO58 |
| A | GLN59 |
| B | LEU50 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD A 150 |
| Chain | Residue |
| A | ASN38 |
| A | GLY78 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD A 151 |
| Chain | Residue |
| A | LYS140 |
| A | TRP27 |
| A | GLN137 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD B 148 |
| Chain | Residue |
| B | GLU60 |
| B | LYS110 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Motif: {"description":"DXXLL motif involved in the interaction with GGA1","evidences":[{"source":"PubMed","id":"20015111","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18088087","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
