3G0J
Crystal Structure of the fifth Bromodomain of Human Poly-bromodomain containing protein 1 (PB1)
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 2 |
| Chain | Residue |
| A | HOH183 |
| A | HOH214 |
| A | MET672 |
| A | LYS676 |
| A | HIS680 |
| A | ASP695 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1 |
| Chain | Residue |
| B | THR667 |
| B | LYS669 |
| A | TYR714 |
| B | HOH182 |
| B | LEU666 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B 3 |
| Chain | Residue |
| B | EDO4 |
| B | HOH165 |
| B | PRO656 |
| B | SER657 |
| B | ARG658 |
| B | LEU661 |
| B | TYR706 |
| B | NO3735 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 4 |
| Chain | Residue |
| B | EDO3 |
| B | LEU655 |
| B | SER657 |
| B | ASN707 |
| B | ILE713 |
| B | NO3735 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NO3 B 735 |
| Chain | Residue |
| B | EDO3 |
| B | EDO4 |
| B | HOH19 |
| B | PRO656 |
| B | TYR664 |
| B | ASN702 |
| B | ALA703 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 58 |
| Details | BROMODOMAIN_1 Bromodomain signature. SaiFlrlpSrselp..DYYltIkkpMdmekIrshmmank..Yqdidsmvedfvm.MfnNActY |
| Chain | Residue | Details |
| A | SER649-TYR706 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 220 |
| Details | Domain: {"description":"Bromo 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00035","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25755297","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
