3FUX
T. thermophilus 16S rRNA A1518 and A1519 methyltransferase (KsgA) in complex with 5'-methylthioadenosine in space group P212121
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000154 | biological_process | rRNA modification |
| A | 0000179 | molecular_function | rRNA (adenine-N6,N6-)-dimethyltransferase activity |
| A | 0003723 | molecular_function | RNA binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006364 | biological_process | rRNA processing |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0016433 | molecular_function | rRNA (adenine) methyltransferase activity |
| A | 0031167 | biological_process | rRNA methylation |
| A | 0032259 | biological_process | methylation |
| A | 0052908 | molecular_function | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity |
| B | 0000154 | biological_process | rRNA modification |
| B | 0000179 | molecular_function | rRNA (adenine-N6,N6-)-dimethyltransferase activity |
| B | 0003723 | molecular_function | RNA binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006364 | biological_process | rRNA processing |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0016433 | molecular_function | rRNA (adenine) methyltransferase activity |
| B | 0031167 | biological_process | rRNA methylation |
| B | 0032259 | biological_process | methylation |
| B | 0052908 | molecular_function | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity |
| C | 0000154 | biological_process | rRNA modification |
| C | 0000179 | molecular_function | rRNA (adenine-N6,N6-)-dimethyltransferase activity |
| C | 0003723 | molecular_function | RNA binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006364 | biological_process | rRNA processing |
| C | 0008168 | molecular_function | methyltransferase activity |
| C | 0016433 | molecular_function | rRNA (adenine) methyltransferase activity |
| C | 0031167 | biological_process | rRNA methylation |
| C | 0032259 | biological_process | methylation |
| C | 0052908 | molecular_function | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE MTA A 272 |
| Chain | Residue |
| A | PHE25 |
| A | ASP99 |
| A | ALA100 |
| A | ASN117 |
| A | LEU118 |
| A | PRO119 |
| A | HIS121 |
| A | GLY26 |
| A | GLN27 |
| A | ASN28 |
| A | GLY54 |
| A | GLY56 |
| A | ILE74 |
| A | GLU75 |
| A | LYS76 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE MTA B 272 |
| Chain | Residue |
| B | PHE25 |
| B | GLY26 |
| B | GLN27 |
| B | ASN28 |
| B | GLY54 |
| B | GLY56 |
| B | ILE74 |
| B | GLU75 |
| B | LYS76 |
| B | ASP99 |
| B | ALA100 |
| B | ASN117 |
| B | PRO119 |
| B | HIS121 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE MTA C 272 |
| Chain | Residue |
| C | PHE25 |
| C | GLY26 |
| C | GLN27 |
| C | ASN28 |
| C | GLY54 |
| C | GLY56 |
| C | ILE74 |
| C | GLU75 |
| C | LYS76 |
| C | ASP99 |
| C | ALA100 |
| C | ASN117 |
| C | PRO119 |
| C | HIS121 |
| C | HOH403 |
Functional Information from PROSITE/UniProt
| site_id | PS01131 |
| Number of Residues | 28 |
| Details | RRNA_A_DIMETH Ribosomal RNA adenine dimethylases signature. VFEvGPGlGaLTralLeagae...VtAIEkD |
| Chain | Residue | Details |
| A | VAL50-ASP77 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 9 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00607 |
| Chain | Residue | Details |
| A | ASN28 | |
| A | LEU30 | |
| A | GLY54 | |
| B | ASN28 | |
| B | LEU30 | |
| B | GLY54 | |
| C | ASN28 | |
| C | LEU30 | |
| C | GLY54 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU75 | |
| A | ASP99 | |
| A | ASN117 | |
| B | GLU75 | |
| B | ASP99 | |
| B | ASN117 | |
| C | GLU75 | |
| C | ASP99 | |
| C | ASN117 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1qam |
| Chain | Residue | Details |
| A | GLY54 | |
| A | GLU75 | |
| A | ASN117 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1qam |
| Chain | Residue | Details |
| B | GLY54 | |
| B | GLU75 | |
| B | ASN117 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1qam |
| Chain | Residue | Details |
| C | GLY54 | |
| C | GLU75 | |
| C | ASN117 |
